Aptevo Therapeutics Inc.

APVO Healthcare Biotechnology

Aptevo Therapeutics Inc.’s revenue for fiscal 2022 (year ended December 2022) was $3.1 million. In the quarter to June 2026, EPS grew 96.5% and free cash flow grew 23.1%, each against the same quarter a year earlier. Insiders bought in the last twelve months.

1.62 0.08 −4.71%
Market cap
$3.1M
P/E
0.0×
Fwd P/E
−0.5×
Dividend yield
—
F-score
4/9
Altman Z
256174.47
Beneish M
3.69
Dividend safety
n/a

Insider Decisions trades per month

Total buys 0.02
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy 1 — — — — — — — — — — —
Sell — — — — — — — — — — — —
Insider Ownership 0.00%

Capital & Financial Ratios $m

Market Cap 3.08
Revenue 12.99
Net Income (26.41)
Free Cash Flow (25.34)
Net Debt (9.80)
Current Ratio 2.08 (at or above 1.5: strong)
Debt/Equity 0.00 (at or below 0.5: strong)
P/E ratio 0.00
Fwd P/E (0.49) (negative: loss-making)
P/S ratio 0.15
P/B ratio 0.32
Past 5Y EPS Growth —
This Y EPS Growth 80.47% (at or above 15%: strong)
Next Y EPS Growth 61.33% (at or above 15%: strong)
Next Y revenue growth (100.00%) (below 0%: weak)
Next 5Y EPS Growth 58.56% (at or above 15%: strong)

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/E against its own 10 years 18.77%
10-year low 10-year high
P/S against its own 10 years 14.06%
10-year low 10-year high
P/B against its own 10 years 12.99%
10-year low 10-year high
EV/FCF against its own 10 years 32.00%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
2017 Powerpack
special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 17 9 22 10
Receivables — — — —
Inventory — — — —
Other 1 0 — —
19 11 23 11
2023 2024 2025 Q'26
Payables 4 1 1 1
ST’ Debt — — — —
Other 1 1 — —
7 6 6 5

Compound Annual Growth %

10y 5y 3y
Sales — (26.64%) (54.21%)
Cash Flow 0.00% 0.00% 0.00%
Earnings 0.00% 0.00% 0.00%
Book Value (15.03%) 0.93% (1.11%)

Revenue $m

Mar Jun Sep Dec Year
’26 — — — — —
’22 3 — — — 3
’21 2 3 3 4 12
’20 — 0 1 2 4
’19 7 7 9 9 32
’18 4 7 6 6 23
’17 2 4 6 3 15
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (8) (5) — — —
’25 (7) (7) (7) (5) (26)
’24 (7) (6) (5) (6) (24)
’23 5 (5) (6) (5) (12)
’22 (5) (3) (7) (6) (21)
’21 (8) (5) (5) (4) (22)
’20 (11) (5) (7) (6) (29)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (8) (5) — — —
’25 (7) (7) (7) (5) (26)
’24 (7) (6) (5) (6) (24)
’23 5 (5) (6) (5) (12)
’22 (5) (3) (7) (6) (21)
’21 (8) (5) (5) (4) (22)
’20 (11) (5) (7) (6) (29)
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 (6.41) (5.31) — — —
’25 (1.58k) (151.08) (40.11) 1.68k (87.27)
’24 (129.68k) (21.77k) (6.26k) 129.67k (31.43k)
’23 223.92k (706.20k) (287.07k) (66.53k) (815.28k)
’22 (889.92k) 3.20m (861.21k) (0.94) 901.40k
’21 (941.59k) (1.00m) (821.02k) (1.25) (3.49m)
’20 510.99k (2.10) (1.21m) (1.92) (5.23)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low 13,866,653.00 9,419,478.00 9,107,683.00 4,020,508.75 1,723,075.25 3,739,190.50 1,136,995.25 89,084.16 1,314.00 9.07

Analyst estimates 2026–2028

Powerpack
High 68,020,448.00 36,923,040.00 52,102,512.00 16,410,240.00 35,164,800.00 25,324,516.00 5,010,984.00 1,512,086.38 143,856.00 1,976.40
People
People Employees 118 121 118 80 58 54 45 40 42 36
Revenue/emp, $m 0.08 0.12 0.20 0.41 0.07 0.23 0.07 0.00 0.00 0.00
Income, $m
Income, $m Revenue 10 15 23 32 4 12 3 — — —
Gross margin, % (24.86) 65.82 51.39 (6.89) 100.00 100.00 100.00 — — —
EBT (140) (56) (54) (43) (31) (29) 7 (19) (24) (26)
EBT margin, % (1,397.93) (381.31) (232.75) (132.82) (717.64) (239.25) 225.24 0.00 0.00 0.00
Net income (112) 7 (54) (40) (18) (28) 8 (17) (24) (26)
Depreciation 3 3 2 2 1 1 1 1 0 0
Per share, $
Per share, $ Revenue 0.49 0.69 1.03 11.12 1.27 2.62 0.61 0.00 0.00 0.00
Earnings (44,628,780.00) 2,653,603.00 (2.39) (7,963,367.00) (2,895,514.00) (3,485,050.00) 901,404.90 (815,283.40) (31,431.65) (87.27)
Cash flow (1.82) (1.95) (2.29) (14.53) (8.65) (4.62) (4.12) 0.00 (29,731.25) (81.12)
Capex (0.12) (0.07) (0.04) (0.05) (0.03) (0.15) (0.01) 0.00 0.00 0.00
Free cash flow (1.95) (2.01) (2.33) (14.58) (8.67) (4.78) (4.13) 0.00 (29,731.25) (81.12)
Book value 2.50 3.85 1.35 4.06 4.89 0.26 3.52 0.00 5,943.75 55.09
Shares, m 20 21 23 3 3 5 5 0 0 0
Valuation, ×
Valuation, × P/E 0.00 6.38 0.00 0.00 0.00 0.00 0.92 — — —
P/S 41,578,223.25 56,728,401.70 10,164,405.30 483,499.54 5,460,128.21 1,759,124.90 527,133.51 — — —
P/B 8,210,231.36 10,136,221.27 7,711,054.96 1,323,846.41 4,389,424.51 17,782,206.63 380,818.33 — — —
EV/Sales 41,578,219.60 56,728,397.46 10,164,404.99 483,499.87 5,460,126.90 1,759,122.38 527,132.03 — — —
EV/FCF (10,543,976.30) (19,349,036.65) (4,474,642.73) (368,558.40) (2,476,980.64) (965,663.29) (323,341.18) — — —
Cash, $m
Cash, $m Operating cash flow (37) (42) (51) (42) (29) (22) (21) (12) (24) (26)
Capex (3) (1) (1) 0 0 (1) 0 — — —
Free cash flow (39) (43) (52) (43) (29) (22) (21) (12) (24) (26)
Balance, $m
Balance, $m Working capital 52 77 31 (8) 33 18 19 12 4 17
Total debt 18 19 19 23 25 15 3 — — —
Net debt (37) (62) (11) 11 (17) (31) (19) (17) (9) (22)
Shareholders’ equity 51 82 30 12 17 1 18 12 5 17
Returns, %
Returns, % ROA (102.37) 6.68 (58.20) (66.91) (33.19) (51.67) 17.68 (58.96) (119.36) (128.73)
ROIC (618.46) (169.33) (169.51) (113.36) 0.00 0.00 0.00 0.00 0.00 0.00
ROE (161.53) 10.52 (95.50) (191.48) (124.84) (319.56) 83.66 (115.32) (284.28) (248.81)
Negative figures in brackets.

All 10 years →

Fiscal years to Dec 2022 · latest quarter Mar 2022

Charts ten years each

Aptevo Therapeutics Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
ADXN Addex Therapeutics Ltd. Sponsored ADR $3.2M — (loss-making) — (loss-making) −100.78% (below 0%: shrinking) n/m −2.73% (below 0%: shrinking) 100.00% 0.00% Compare
CLDI Calidi Biotherapeutics, Inc. $3.2M — (loss-making) — — n/m +11.16% (above 0%: growing) — 0.00% Compare
EOCN Eocene Ltd. $3.2M — (loss-making) — (loss-making) −100.00% (below 0%: shrinking) n/m −67.74% (below 0%: shrinking) 0.00% 0.00% Compare
SXTP 60 Degrees Pharmaceuticals Inc. $3.2M — (loss-making) — (loss-making) −32.48% (below 0%: shrinking) n/m −54.33% (below 0%: shrinking) 27.32% (1,092.40%) Compare
APVO Aptevo Therapeutics Inc. $3.1M 0.0× — (loss-making) +28.62% (above 0%: growing) n/m +23.11% (above 0%: growing) 0.00% 0.00%
GRI GRI Bio, Inc. $3.1M 0.0× — (loss-making) — n/m +54.33% (above 0%: growing) 0.00% 0.00% Compare
REVB Revelation Biosciences, Inc. $3.0M — (loss-making) — — n/m −35.29% (below 0%: shrinking) 0.00% 0.00% Compare
ARAV ARAVIVE, INC $3.0M — (loss-making) — (loss-making) −44.39% (below 0%: shrinking) n/m +48.19% (above 0%: growing) 100.00% (323.44%) Compare
DCOY Decoy Therapeutics Inc $2.9M 0.0× — (loss-making) −84.61% (below 0%: shrinking) n/m −212.47% (below 0%: shrinking) 100.00% (1,055.98%) Compare
Median of peers $3.1M — — −84.61% — −19.01% 27.32% 0.00%

All 614 Biotechnology stocks →

Aptevo Therapeutics Inc. (APVO) key facts

  • Aptevo Therapeutics Inc. (APVO) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • Aptevo Therapeutics Inc.’s revenue for fiscal 2022 (year ended December 2022) was $3.1 million.
  • As of October 16, 2026, APVO traded at $1.62, a market capitalization of $3.1 million.
  • Return on equity was −248.8% and debt-to-equity 0.00.
  • Its Piotroski F-score is 4 out of 9 and its Altman Z-score is 256174.47 (safe zone) for fiscal 2022.

Source: company filings (standardised) and stockrow calculations.

Aptevo Therapeutics Inc. (APVO) Latest News

stockrow.com/APVO · Data as of Mar 31, 2022 · For information only; not investment advice. · © 2026 stockrow.com