Prime Medicine, Inc. (PRME) vs Syndax Pharmaceuticals, Inc. (SNDX)

Prime Medicine, Inc. and Syndax Pharmaceuticals, Inc. are both Biotechnology companies. Prime Medicine, Inc. and Syndax Pharmaceuticals, Inc. are of similar size ($843.6M and $807.1M). Syndax Pharmaceuticals, Inc. grew revenue faster over the last twelve months: 159.5% against −17.9%. Syndax Pharmaceuticals, Inc. has the higher net margin (−72.4% vs −4,613.1%) and the lower return on invested capital (−83.4% vs 0.00%). Across the 16 metrics below, Syndax Pharmaceuticals, Inc. leads on 10 and Prime Medicine, Inc. on 6.

Valuation

Metric PRME SNDX Biotechnology median
P/E n/m n/m 10.60
P/S 200.59 2.96 9.40
P/B 20.52 n/m 2.13
Price to free cash flow n/m n/m 25.18
EV/EBITDA n/m n/m 0.66
EV/Sales 177.25 3.56 9.02
Earnings yield (23.95%) (24.74%) (32.88%)
Free cash flow yield (19.20%) (20.73%) (23.13%)

Profitability

Metric PRME SNDX Biotechnology median
Gross margin 100.00% 92.21% 68.51%
Operating margin (4,824.94%) (61.72%) 0.00%
Net margin (4,613.11%) (72.38%) 0.00%
Free cash flow margin (3,850.92%) (61.36%) 0.00%
Return on equity (373.29%) (426.43%) (51.96%)
Return on assets (71.16%) (33.67%) (46.06%)
Return on invested capital 0.00% (83.42%) 0.00%

Growth

Metric PRME SNDX Biotechnology median
Revenue growth (TTM) (17.90%) 159.46% 6.76%
EPS growth (last fiscal year) 18.18% 11.56% 29.88%
Revenue growth, 5-year CAGR — 157.68% 9.75%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric PRME SNDX Biotechnology median
Debt to equity 0.00 (34.24) 0.00
Current ratio 3.05 4.69 4.97
Net debt to EBITDA 0.88 0.25 1.01

Dividend

Metric PRME SNDX Biotechnology median
Dividend yield — — 0.41%
Payout ratio — — —

Size

Metric PRME SNDX Biotechnology median
Market cap 807.12m 843.57m 161.82m

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