Prelude Therapeutics Incorporated (PRLD) vs Vanda Pharmaceuticals Inc. (VNDA)

Prelude Therapeutics Incorporated and Vanda Pharmaceuticals Inc. are both Biotechnology companies. Prelude Therapeutics Incorporated and Vanda Pharmaceuticals Inc. are of similar size ($265.0M and $256.4M). Vanda Pharmaceuticals Inc. has the higher net margin (−127.4% vs −269.8%) and the lower return on invested capital (−217.6% vs 0.00%). Across the 16 metrics below, Prelude Therapeutics Incorporated leads on 10 and Vanda Pharmaceuticals Inc. on 6.

Valuation

Metric PRLD VNDA Biotechnology median
P/E n/m n/m 8.50
P/S 14.30 1.13 9.71
P/B 2.40 1.10 2.13
Price to free cash flow n/m n/m 20.82
EV/EBITDA n/m n/m 0.64
EV/Sales 7.54 0.35 9.21
Earnings yield (22.39%) (114.89%) (33.15%)
Free cash flow yield (10.39%) (63.04%) (25.50%)

Profitability

Metric PRLD VNDA Biotechnology median
Gross margin 100.00% 93.74% 65.16%
Operating margin (300.56%) (86.07%) 0.00%
Net margin (269.75%) (127.41%) 0.00%
Free cash flow margin (148.30%) (70.93%) 0.00%
Return on equity (57.73%) (77.81%) (56.36%)
Return on assets (39.76%) (53.00%) (48.04%)
Return on invested capital 0.00% (217.59%) 0.00%

Growth

Metric PRLD VNDA Biotechnology median
Revenue growth (TTM) — 6.02% 6.02%
EPS growth (last fiscal year) 23.21% (1,033.33%) 30.26%
Revenue growth, 5-year CAGR — (2.73%) 9.41%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric PRLD VNDA Biotechnology median
Debt to equity 0.00 0.01 0.00
Current ratio 4.07 1.61 4.72
Net debt to EBITDA 1.00 1.84 0.96

Dividend

Metric PRLD VNDA Biotechnology median
Dividend yield — — 0.09%
Payout ratio — — —

Size

Metric PRLD VNDA Biotechnology median
Market cap 264.95m 256.36m 135.18m

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