Niagen Bioscience, Inc. (NAGE) vs ProQR Therapeutics N.V. (PRQR)

Niagen Bioscience, Inc. and ProQR Therapeutics N.V. are both Biotechnology companies. Niagen Bioscience, Inc. and ProQR Therapeutics N.V. are of similar size ($238.2M and $236.1M). ProQR Therapeutics N.V. has negative trailing earnings, so its P/E is not meaningful; Niagen Bioscience, Inc. trades at 15.2×. ProQR Therapeutics N.V. grew revenue faster over the last twelve months: 19.7% against 11.0%. Niagen Bioscience, Inc. has the higher net margin (12.4% vs −228.7%) and the higher return on invested capital (42.0% vs 0.00%). Across the 17 metrics below, Niagen Bioscience, Inc. leads on 14 and ProQR Therapeutics N.V. on 3.

Valuation

Metric NAGE PRQR Biotechnology median
P/E 15.20 n/m 7.88
P/S 1.87 8.45 11.47
P/B 2.92 1.96 2.52
Price to free cash flow 21.05 n/m 21.16
EV/EBITDA 15.14 n/m 0.74
EV/Sales 1.36 2.60 10.73
Earnings yield 6.58% (27.88%) (28.84%)
Free cash flow yield 4.75% (31.63%) (23.03%)

Profitability

Metric NAGE PRQR Biotechnology median
Gross margin 64.24% 100.00% 65.16%
Operating margin 8.21% (233.33%) 0.00%
Net margin 12.39% (228.71%) 0.00%
Free cash flow margin 8.89% (267.36%) 0.00%
Return on equity 21.80% (58.29%) (57.72%)
Return on assets 16.14% (31.53%) (49.22%)
Return on invested capital 41.95% 0.00% 0.00%

Growth

Metric NAGE PRQR Biotechnology median
Revenue growth (TTM) 10.99% 19.72% 5.64%
EPS growth (last fiscal year) 81.82% (28.57%) —
Revenue growth, 5-year CAGR 16.91% — 8.40%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric NAGE PRQR Biotechnology median
Debt to equity 0.00 0.06 0.00
Current ratio 6.50 3.49 4.73
Net debt to EBITDA (3.80) 2.15 0.96

Dividend

Metric NAGE PRQR Biotechnology median
Dividend yield — — 2.10%
Payout ratio 0.00 0.00 0.00

Size

Metric NAGE PRQR Biotechnology median
Market cap 238.17m 236.13m 162.10m

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