Saturday 17 October 2026
Export PRQR’s income statement to Excel — free account
ProQR Therapeutics N.V.
PRQR Healthcare Biotechnology
ProQR Therapeutics N.V.’s revenue for fiscal 2025 (year ended December 2025) was $18.0 million, down 12.0% from fiscal 2024. In the quarter to June 2026, revenue grew 135.0%, EPS grew 28.6%, free cash flow fell 1.06% and total debt rose 8.71%, each against the same quarter a year earlier. Insiders bought in the last twelve months.
1.31
0.14
−9.66%
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Target Price Range
Analyst price targets
Free accountTen years at a glance Fiscal years to December
| Group | Line | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Trend | 2026e | 2027e | 2028e |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Price, $ | |||||||||||||||
| Price, $ | Low | 3.48 | 2.75 | 2.80 | 5.49 | 3.40 | 4.00 | 0.53 | 1.11 | 1.61 | 1.07 |
Analyst estimates 2026–2028 Powerpack |
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| High | 8.96 | 6.90 | 24.00 | 18.94 | 10.09 | 9.46 | 8.60 | 3.85 | 4.62 | 3.10 | |||||
| People | |||||||||||||||
| People | Employees | 133 | 130 | 118 | 154 | 150 | 182 | 130 | 156 | 166 | 187 | ||||
| Revenue/emp, $m | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.01 | 0.03 | 0.05 | 0.12 | 0.10 | |||||
| Income, $m | |||||||||||||||
| Income, $m | Revenue | — | — | — | — | — | 2 | 4 | 7 | 20 | 18 | ||||
| Gross margin, % | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 100.00 | 100.00 | 100.00 | 100.00 | 100.00 | |||||
| EBT | (43) | (49) | (44) | (63) | (53) | (73) | (68) | (30) | (30) | (48) | |||||
| EBT margin, % | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | (4,546.80) | (1,605.02) | (426.97) | (147.90) | (265.09) | |||||
| Net income | (43) | (49) | (44) | (64) | (53) | (73) | (68) | (30) | (30) | (48) | |||||
| Depreciation | 1 | 1 | 1 | 2 | 3 | 3 | 3 | 3 | 3 | 3 | |||||
| Per share, $ | |||||||||||||||
| Per share, $ | Revenue | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.03 | 0.06 | 0.09 | 0.24 | 0.17 | ||||
| Earnings | (1.85) | (1.94) | (1.29) | (1.55) | (1.06) | (1.14) | (0.96) | (0.38) | (0.35) | (0.45) | |||||
| Cash flow | (1.62) | (1.56) | (0.99) | (1.20) | (1.07) | (0.48) | (1.01) | 0.29 | (0.46) | (0.57) | |||||
| Capex | (0.12) | (0.01) | (0.01) | (0.02) | (0.02) | (0.01) | (0.01) | 0.09 | (0.02) | (0.01) | |||||
| Free cash flow | (1.74) | (1.56) | (1.00) | (1.22) | (1.09) | (0.49) | (1.02) | 0.38 | (0.48) | (0.58) | |||||
| Book value | 2.52 | 1.75 | 3.21 | 2.56 | 1.29 | 2.09 | 0.96 | 0.55 | 1.11 | 0.53 | |||||
| Shares, m | 23 | 25 | 34 | 41 | 50 | 64 | 72 | 81 | 86 | 105 | |||||
| Valuation, × | |||||||||||||||
| Valuation, × | P/E | — | — | — | — | — | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | ||||
| P/S | — | — | — | — | — | 0.00 | 57.44 | 23.90 | 11.15 | 11.82 | |||||
| P/B | — | — | — | — | — | 3.84 | 3.56 | 3.76 | 2.38 | 3.81 | |||||
| EV/Sales | — | — | — | — | — | 0.00 | 35.64 | 6.66 | 3.72 | 6.58 | |||||
| EV/FCF | — | — | — | — | — | (11.01) | (2.08) | 2.15 | (1.86) | (1.94) | |||||
| Cash, $m | |||||||||||||||
| Cash, $m | Operating cash flow | (38) | (40) | (34) | (49) | (54) | (31) | (72) | 23 | (39) | (60) | ||||
| Capex | (3) | 0 | 0 | (1) | (1) | (1) | (1) | 7 | (2) | (1) | |||||
| Free cash flow | (41) | (40) | (34) | (50) | (55) | (31) | (73) | 30 | (41) | (61) | |||||
| Balance, $m | |||||||||||||||
| Balance, $m | Working capital | 61 | 48 | 118 | 116 | 80 | 194 | 140 | 94 | 124 | 77 | ||||
| Total debt | 6 | 8 | 11 | 15 | 20 | 52 | 7 | 5 | 5 | 6 | |||||
| Net debt | (59) | (46) | (114) | (111) | (67) | (170) | (93) | (124) | (157) | (99) | |||||
| Shareholders’ equity | 59 | 44 | 109 | 105 | 65 | 134 | 69 | 45 | 96 | 56 | |||||
| Returns, % | |||||||||||||||
| Returns, % | ROA | (47.11) | (74.42) | (45.82) | (48.55) | (43.52) | (40.42) | (32.02) | (18.46) | (18.15) | (30.86) | ||||
| ROIC | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |||||
| ROE | (54.60) | (95.54) | (56.62) | (59.24) | (62.69) | (73.43) | (67.73) | (53.67) | (42.73) | (62.93) | |||||
Negative figures in brackets.
Fiscal years to Dec 2025 · latest quarter Jun 2026
Charts ten years each
ProQR Therapeutics N.V. vs peers in Biotechnology (Q) = latest quarter vs a year earlier
| Company | Market cap | P/E | Fwd P/E | Revenue growth (Q) | EPS growth (Q) | FCF growth (Q) | Gross margin (Q) | EBIT margin (Q) | Compare |
|---|---|---|---|---|---|---|---|---|---|
| IFRX InflaRx N.V. | $212.2M | — (loss-making) | — (loss-making) | −128.93% (below 0%: shrinking) | n/m | +69.33% (above 0%: growing) | 14,029.95% | 0.00% | Compare |
| ZNTL Zentalis Pharmaceuticals, Inc. | $212.1M | — (loss-making) | — (loss-making) | — | n/m | −9.06% (below 0%: shrinking) | 100.00% | 0.00% | Compare |
| LRMR Larimar Therapeutics, Inc. | $206.7M | — (loss-making) | — | — | n/m | −127.63% (below 0%: shrinking) | 0.00% | 0.00% | Compare |
| PRQR ProQR Therapeutics N.V. | $204.6M | — (loss-making) | — (loss-making) | +135.03% (above 0%: growing) | n/m | −1.06% (below 0%: shrinking) | 100.00% | (100.72%) | |
| NAGE Niagen Bioscience, Inc. | $204.2M | 12.5× | 15.0× | −4.28% (below 0%: shrinking) | −80.00% (below 0%: shrinking) | +140.63% (above 0%: growing) | 64.84% | 2.35% | Compare |
| LYEL Lyell Immunopharma, Inc. | $200.7M | — (loss-making) | — (loss-making) | −50.00% (below 0%: shrinking) | n/m | +1.31% (above 0%: growing) | 100.00% | (1,183,425.00%) | Compare |
| RNAC Cartesian Therapeutics, Inc. | $199.1M | — (loss-making) | — (loss-making) | −92.91% (below 0%: shrinking) | −7.84% (below 0%: shrinking) | −6.15% (below 0%: shrinking) | 100.00% | 0.00% | Compare |
| IVVD Invivyd, Inc. | $197.1M | — (loss-making) | — (loss-making) | +21.20% (above 0%: growing) | n/m | −226.89% (below 0%: shrinking) | 91.09% | (320.76%) | Compare |
| CGEN Compugen Ltd. | $197.0M | 5.2× | — (loss-making) | +107.00% (above 0%: growing) | n/m | −155.42% (below 0%: shrinking) | (3.54%) | (339.62%) | Compare |
| Median of peers | $202.4M | — | — | −27.14% | — | −7.60% | 95.55% | 0.00% |
ProQR Therapeutics N.V. (PRQR) key facts
- Concern: ProQR Therapeutics N.V.’s revenue for fiscal 2025 (year ended December 2025) was $18.0 million, down 12.0% from fiscal 2024.
- Concern: ProQR Therapeutics N.V. reported a net loss of $47.7 million, or a loss of $0.45 per share, for fiscal 2025.
- ProQR Therapeutics N.V. (PRQR) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
- As of October 16, 2026, PRQR traded at $1.31, a market capitalization of $204.6 million.
- Trailing earnings are negative, so a P/E ratio is not meaningful; the stock trades at 6.7× sales.
- Return on equity was −62.9% and debt-to-equity 0.06.
- Its Piotroski F-score is 1 out of 9 and its Altman Z-score is −4.43 (distress zone) for fiscal 2025.