Kymera Therapeutics, Inc. (KYMR) vs Protagonist Therapeutics, Inc. (PTGX)

Kymera Therapeutics, Inc. and Protagonist Therapeutics, Inc. are both Biotechnology companies. Kymera Therapeutics, Inc. and Protagonist Therapeutics, Inc. are of similar size ($9.7B and $8.9B). Kymera Therapeutics, Inc. has negative trailing earnings, so its P/E is not meaningful; Protagonist Therapeutics, Inc. trades at 117×. Kymera Therapeutics, Inc. grew revenue faster over the last twelve months: 134.8% against 34.8%. Protagonist Therapeutics, Inc. has the higher net margin (29.4% vs −285.3%) and the higher return on invested capital (61.8% vs −26.7%). Across the 17 metrics below, Protagonist Therapeutics, Inc. leads on 13 and Kymera Therapeutics, Inc. on 4.

Valuation

Metric KYMR PTGX Biotechnology median
P/E n/m 116.99 7.88
P/S 105.17 33.37 11.47
P/B 7.32 11.18 2.52
Price to free cash flow n/m 72.07 21.16
EV/EBITDA n/m 153.05 0.74
EV/Sales 98.60 30.60 10.73
Earnings yield (2.88%) 0.85% (28.84%)
Free cash flow yield (2.15%) 1.39% (23.03%)

Profitability

Metric KYMR PTGX Biotechnology median
Gross margin 100.00% 100.00% 65.16%
Operating margin (333.50%) 20.69% 0.00%
Net margin (285.33%) 29.40% 0.00%
Free cash flow margin (226.62%) 46.31% 0.00%
Return on equity (24.15%) 10.98% (57.72%)
Return on assets (21.58%) 10.34% (49.22%)
Return on invested capital (26.72%) 61.84% 0.00%

Growth

Metric KYMR PTGX Biotechnology median
Revenue growth (TTM) 134.84% 34.81% 5.64%
EPS growth (last fiscal year) (23.83%) (148.46%) —
Revenue growth, 5-year CAGR 2.87% 9.96% 8.40%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric KYMR PTGX Biotechnology median
Debt to equity 0.00 0.00 0.00
Current ratio 10.34 21.71 4.73
Net debt to EBITDA 2.42 3.49 0.96

Dividend

Metric KYMR PTGX Biotechnology median
Dividend yield — — 2.10%
Payout ratio 0.00 0.00 0.00

Size

Metric KYMR PTGX Biotechnology median
Market cap 9.69b 8.88b 162.10m

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