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Iovance Biotherapeutics, Inc. (IOVA) vs Xenon Pharmaceuticals Inc. (XENE)

Iovance Biotherapeutics, Inc. and Xenon Pharmaceuticals Inc. are both Biotechnology companies. Iovance Biotherapeutics, Inc. and Xenon Pharmaceuticals Inc. are of similar size ($3.7B and $3.5B). Iovance Biotherapeutics, Inc. grew revenue faster over the last twelve months: 51.3% against −8.15%. Xenon Pharmaceuticals Inc. has the higher net margin (0.00% vs −58.2%) and the lower return on invested capital (−88.5% vs −17.7%). Across the 16 metrics below, Iovance Biotherapeutics, Inc. leads on 10 and Xenon Pharmaceuticals Inc. on 6.

Valuation

Metric IOVA XENE Biotechnology median
P/E n/m n/m 10.26
P/S 9.29 222.58 9.18
P/B 4.33 3.03 2.05
Price to free cash flow n/m n/m 24.81
EV/EBITDA n/m n/m 0.65
EV/Sales 8.51 169.19 8.98
Earnings yield (6.78%) (12.53%) (34.89%)
Free cash flow yield (6.14%) (8.98%) (24.52%)

Profitability

Metric IOVA XENE Biotechnology median
Gross margin 0.00% 28.40% 65.16%
Operating margin (60.79%) 0.00% 0.00%
Net margin (58.19%) 0.00% 0.00%
Free cash flow margin (57.01%) 0.00% 0.00%
Return on equity (29.11%) (43.62%) (50.12%)
Return on assets (23.26%) (41.54%) (45.60%)
Return on invested capital (17.72%) (88.54%) 0.00%

Growth

Metric IOVA XENE Biotechnology median
Revenue growth (TTM) 51.34% (8.15%) 6.26%
EPS growth (last fiscal year) 14.84% (44.85%) 29.88%
Revenue growth, 5-year CAGR — 89.00% 9.75%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric IOVA XENE Biotechnology median
Debt to equity 0.00 0.00 0.00
Current ratio 5.20 21.02 4.89
Net debt to EBITDA 0.82 1.48 1.01

Dividend

Metric IOVA XENE Biotechnology median
Dividend yield — — 0.41%
Payout ratio — — —

Size

Metric IOVA XENE Biotechnology median
Market cap 3.51b 3.65b 172.11m

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