Denali Therapeutics Inc. (DNLI) vs Nurix Therapeutics, Inc. (NRIX)

Denali Therapeutics Inc. and Nurix Therapeutics, Inc. are both Biotechnology companies. Denali Therapeutics Inc. and Nurix Therapeutics, Inc. are of similar size ($2.9B and $2.7B). Denali Therapeutics Inc. has negative trailing earnings, so its P/E is not meaningful; Nurix Therapeutics, Inc. trades at 9.7×. Nurix Therapeutics, Inc. grew revenue faster over the last twelve months: 738.8% against 194.7%. Nurix Therapeutics, Inc. has the higher net margin (42.0% vs −171.1%) and the higher return on invested capital (0.00% vs −260.5%). Across the 18 metrics below, Nurix Therapeutics, Inc. leads on 17 and Denali Therapeutics Inc. on 1.

Valuation

Metric DNLI NRIX Biotechnology median
P/E n/m 9.74 8.50
P/S 11.00 3.88 9.71
P/B 3.94 2.81 2.13
Price to free cash flow n/m 7.37 20.82
EV/EBITDA n/m 5.68 0.64
EV/Sales 8.64 2.39 9.21
Earnings yield (16.17%) 10.27% (33.15%)
Free cash flow yield (13.30%) 13.57% (25.50%)

Profitability

Metric DNLI NRIX Biotechnology median
Gross margin 99.97% 100.00% 65.16%
Operating margin (181.51%) 41.27% 0.00%
Net margin (171.06%) 42.01% 0.00%
Free cash flow margin (146.31%) 52.68% 0.00%
Return on equity (54.93%) 43.99% (56.36%)
Return on assets (44.01%) 34.33% (48.04%)
Return on invested capital (260.54%) 0.00% 0.00%

Growth

Metric DNLI NRIX Biotechnology median
Revenue growth (TTM) 194.68% 738.76% 6.02%
EPS growth (last fiscal year) (15.56%) (5.90%) 30.26%
Revenue growth, 5-year CAGR 20.67% 36.35% 9.41%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric DNLI NRIX Biotechnology median
Debt to equity 0.01 0.00 0.00
Current ratio 8.37 8.44 4.72
Net debt to EBITDA 1.56 2.14 0.96

Dividend

Metric DNLI NRIX Biotechnology median
Dividend yield — — 0.09%
Payout ratio — — —

Size

Metric DNLI NRIX Biotechnology median
Market cap 2.93b 2.73b 135.18m

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