Cytokinetics, Incorporated (CYTK) vs Madrigal Pharmaceuticals, Inc. (MDGL)

Cytokinetics, Incorporated and Madrigal Pharmaceuticals, Inc. are both Biotechnology companies. Madrigal Pharmaceuticals, Inc. is the larger, with a market value of $9.3B against $7.7B — 1.2× the size. Madrigal Pharmaceuticals, Inc. grew revenue faster over the last twelve months: 92.8% against 29.9%. Madrigal Pharmaceuticals, Inc. has the higher net margin (−10.9% vs −686.6%) and the lower return on invested capital (−1,480.3% vs 0.00%). Across the 16 metrics below, Madrigal Pharmaceuticals, Inc. leads on 11 and Cytokinetics, Incorporated on 5.

Valuation

Metric CYTK MDGL Biotechnology median
P/E n/m n/m 10.26
P/S 64.40 8.19 9.18
P/B n/m 18.66 2.05
Price to free cash flow n/m n/m 24.81
EV/EBITDA n/m n/m 0.65
EV/Sales 65.85 7.76 8.98
Earnings yield (10.93%) (1.48%) (34.89%)
Free cash flow yield (8.07%) (1.47%) (24.52%)

Profitability

Metric CYTK MDGL Biotechnology median
Gross margin 0.00% 90.96% 65.16%
Operating margin (625.15%) (10.69%) 0.00%
Net margin (686.63%) (10.89%) 0.00%
Free cash flow margin (519.53%) (11.81%) 0.00%
Return on equity 184.71% (24.82%) (50.12%)
Return on assets (47.70%) (11.12%) (45.60%)
Return on invested capital 0.00% (1,480.32%) 0.00%

Growth

Metric CYTK MDGL Biotechnology median
Revenue growth (TTM) 29.90% 92.80% 6.26%
EPS growth (last fiscal year) (24.33%) 41.32% 29.88%
Revenue growth, 5-year CAGR 9.54% — 9.75%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric CYTK MDGL Biotechnology median
Debt to equity (0.54) 0.54 0.00
Current ratio 3.36 3.05 4.89
Net debt to EBITDA (0.46) 2.21 1.01

Dividend

Metric CYTK MDGL Biotechnology median
Dividend yield — — 0.41%
Payout ratio — — —

Size

Metric CYTK MDGL Biotechnology median
Market cap 7.72b 9.29b 172.11m

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