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Compugen Ltd. (CGEN) vs Sionna Therapeutics, Inc. (SION)

Compugen Ltd. and Sionna Therapeutics, Inc. are both Biotechnology companies. Compugen Ltd. and Sionna Therapeutics, Inc. are of similar size ($187.6M and $185.0M). Sionna Therapeutics, Inc. has negative trailing earnings, so its P/E is not meaningful; Compugen Ltd. trades at 5.5×. Compugen Ltd. has the higher net margin (47.6% vs 0.00%) and the higher return on invested capital (0.00% vs −125.0%). Across the 13 metrics below, Compugen Ltd. leads on 10 and Sionna Therapeutics, Inc. on 3.

Valuation

Metric CGEN SION Biotechnology median
P/E 5.47 n/m 8.42
P/S 2.66 n/m 10.01
P/B 2.22 0.70 2.21
Price to free cash flow 4.92 n/m 21.01
EV/EBITDA 2.36 0.23 0.61
EV/Sales 0.97 n/m 9.41
Earnings yield 18.27% (53.17%) (31.85%)
Free cash flow yield 20.34% (41.21%) (24.58%)

Profitability

Metric CGEN SION Biotechnology median
Gross margin 86.89% — 65.16%
Operating margin 40.94% 0.00% 0.00%
Net margin 47.55% 0.00% 0.00%
Free cash flow margin 54.10% 0.00% 0.00%
Return on equity 47.85% (32.34%) (56.36%)
Return on assets 23.86% (30.66%) (48.04%)
Return on invested capital 0.00% (125.00%) 0.00%

Growth

Metric CGEN SION Biotechnology median
Revenue growth (TTM) 234.18% — 6.02%
EPS growth (last fiscal year) 337.50% 88.24% 30.26%
Revenue growth, 5-year CAGR 105.20% — 9.41%
Net income growth, 5-year CAGR 0.00% — 0.00%

Health

Metric CGEN SION Biotechnology median
Debt to equity 0.00 0.00 0.00
Current ratio 5.72 20.05 4.72
Net debt to EBITDA (4.65) 2.58 0.96

Dividend

Metric CGEN SION Biotechnology median
Dividend yield — — 0.08%
Payout ratio — — —

Size

Metric CGEN SION Biotechnology median
Market cap 187.56m 184.98m 132.35m

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