Biofrontera Inc. (BFRI) vs Shuttle Pharmaceuticals Holdings, Inc. (SHPH)

Biofrontera Inc. and Shuttle Pharmaceuticals Holdings, Inc. are both Drug Manufacturers Specialty & Generic companies. Shuttle Pharmaceuticals Holdings, Inc. is the larger, with a market value of $26.5M against $12.6M — 2.1× the size. Biofrontera Inc. has negative trailing earnings, so its P/E is not meaningful; Shuttle Pharmaceuticals Holdings, Inc. trades at 0.2×. Shuttle Pharmaceuticals Holdings, Inc. has the higher net margin (0.00% vs −13.8%) and the higher return on invested capital (−36.7% vs −69.5%). Across the 14 metrics below, Shuttle Pharmaceuticals Holdings, Inc. leads on 10 and Biofrontera Inc. on 4.

Valuation

Metric BFRI SHPH Drug Manufacturers Specialty & Generic median
P/E n/m 0.17 19.25
P/S 0.23 n/m 2.11
P/B 1.78 0.27 1.78
Price to free cash flow n/m n/m 16.14
EV/EBITDA n/m n/m 12.58
EV/Sales 0.23 n/m 2.73
Earnings yield (54.88%) 586.62% (4.38%)
Free cash flow yield (74.83%) (129.33%) 0.00%

Profitability

Metric BFRI SHPH Drug Manufacturers Specialty & Generic median
Gross margin 79.25% 0.00% 53.94%
Operating margin (14.22%) 0.00% 0.00%
Net margin (13.78%) 0.00% 0.00%
Free cash flow margin (17.17%) 0.00% 0.00%
Return on equity (988.35%) (90.05%) (0.40%)
Return on assets (28.80%) (72.47%) (3.32%)
Return on invested capital (69.45%) (36.73%) 0.00%

Growth

Metric BFRI SHPH Drug Manufacturers Specialty & Generic median
Revenue growth (TTM) 17.83% — 10.01%
EPS growth (last fiscal year) 67.70% 91.32% 49.06%
Revenue growth, 5-year CAGR 17.21% — 6.74%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric BFRI SHPH Drug Manufacturers Specialty & Generic median
Debt to equity 0.78 0.00 0.05
Current ratio 1.18 0.11 2.31
Net debt to EBITDA 0.17 0.03 0.97

Dividend

Metric BFRI SHPH Drug Manufacturers Specialty & Generic median
Dividend yield — — 1.57%
Payout ratio — — 0.27

Size

Metric BFRI SHPH Drug Manufacturers Specialty & Generic median
Market cap 12.58m 26.54m 276.90m

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