Arcutis Biotherapeutics, Inc. (ARQT) vs Definium Therapeutics, Inc. (DFTX)

Arcutis Biotherapeutics, Inc. and Definium Therapeutics, Inc. are both Biotechnology companies. Definium Therapeutics, Inc. is the larger, with a market value of $4.1B against $3.4B — 1.2× the size. Definium Therapeutics, Inc. has negative trailing earnings, so its P/E is not meaningful; Arcutis Biotherapeutics, Inc. trades at 119×. Arcutis Biotherapeutics, Inc. has the higher net margin (5.88% vs 0.00%) and the higher return on invested capital (23.5% vs 0.00%). Across the 14 metrics below, Arcutis Biotherapeutics, Inc. leads on 10 and Definium Therapeutics, Inc. on 4.

Valuation

Metric ARQT DFTX Biotechnology median
P/E 118.96 n/m 10.26
P/S 7.02 n/m 9.18
P/B 14.64 3.68 2.05
Price to free cash flow 79.88 n/m 24.81
EV/EBITDA 92.82 n/m 0.65
EV/Sales 6.72 n/m 8.98
Earnings yield 0.84% (11.22%) (34.89%)
Free cash flow yield 1.25% (4.97%) (24.52%)

Profitability

Metric ARQT DFTX Biotechnology median
Gross margin 91.18% 0.00% 65.16%
Operating margin 6.91% 0.00% 0.00%
Net margin 5.88% 0.00% 0.00%
Free cash flow margin 11.74% 0.00% 0.00%
Return on equity 14.88% (64.09%) (50.12%)
Return on assets 6.68% (51.35%) (45.60%)
Return on invested capital 23.48% 0.00% 0.00%

Growth

Metric ARQT DFTX Biotechnology median
Revenue growth (TTM) 60.00% — 6.26%
EPS growth (last fiscal year) 88.79% (33.77%) 29.88%
Revenue growth, 5-year CAGR — — 9.75%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric ARQT DFTX Biotechnology median
Debt to equity 0.45 0.04 0.00
Current ratio 2.92 6.95 4.89
Net debt to EBITDA 11.64 2.21 1.01

Dividend

Metric ARQT DFTX Biotechnology median
Dividend yield — — 0.41%
Payout ratio — — —

Size

Metric ARQT DFTX Biotechnology median
Market cap 3.39b 4.08b 172.11m

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