Alnylam Pharmaceuticals, Inc. (ALNY) vs Revolution Medicines, Inc. (RVMD)

Alnylam Pharmaceuticals, Inc. and Revolution Medicines, Inc. are both Biotechnology companies. Revolution Medicines, Inc. is the larger, with a market value of $42.9B against $31.2B — 1.4× the size. Revolution Medicines, Inc. has negative trailing earnings, so its P/E is not meaningful; Alnylam Pharmaceuticals, Inc. trades at 43.6×. Alnylam Pharmaceuticals, Inc. grew revenue faster over the last twelve months: 95.1% against −8.81%. Alnylam Pharmaceuticals, Inc. has the higher net margin (16.1% vs 0.00%) and the higher return on invested capital (0.00% vs 0.00%). Across the 17 metrics below, Alnylam Pharmaceuticals, Inc. leads on 14 and Revolution Medicines, Inc. on 3.

Valuation

Metric ALNY RVMD Biotechnology median
P/E 43.62 n/m 7.88
P/S 7.12 1,606.35 11.47
P/B 25.25 16.59 2.52
Price to free cash flow 41.71 n/m 21.16
EV/EBITDA 30.25 n/m 0.74
EV/Sales 6.64 1,498.51 10.73
Earnings yield 2.29% (4.30%) (28.84%)
Free cash flow yield 2.40% (2.85%) (23.03%)

Profitability

Metric ALNY RVMD Biotechnology median
Gross margin 79.65% 35.06% 65.16%
Operating margin 20.81% 0.00% 0.00%
Net margin 16.13% 0.00% 0.00%
Free cash flow margin 17.07% 0.00% 0.00%
Return on equity 96.55% (79.09%) (57.72%)
Return on assets 15.30% (52.37%) (49.22%)
Return on invested capital 0.00% 0.00% 0.00%

Growth

Metric ALNY RVMD Biotechnology median
Revenue growth (TTM) 95.14% (8.81%) 5.64%
EPS growth (last fiscal year) 206.88% (66.20%) —
Revenue growth, 5-year CAGR 49.77% (10.50%) 8.40%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric ALNY RVMD Biotechnology median
Debt to equity 0.75 0.40 0.00
Current ratio 3.05 11.38 4.73
Net debt to EBITDA (3.41) 1.47 0.96

Dividend

Metric ALNY RVMD Biotechnology median
Dividend yield 2.52% — 2.10%
Payout ratio 0.00 0.00 0.00

Size

Metric ALNY RVMD Biotechnology median
Market cap 31.16b 42.88b 162.10m

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