Agios Pharmaceuticals, Inc. (AGIO) vs Stoke Therapeutics, Inc. (STOK)

Agios Pharmaceuticals, Inc. and Stoke Therapeutics, Inc. are both Biotechnology companies. Agios Pharmaceuticals, Inc. and Stoke Therapeutics, Inc. are of similar size ($1.7B and $1.7B). Agios Pharmaceuticals, Inc. grew revenue faster over the last twelve months: 214.4% against −86.3%. Agios Pharmaceuticals, Inc. has the higher net margin (−264.8% vs −862.1%) and the higher return on invested capital (−75.0% vs −482.0%). Across the 16 metrics below, Agios Pharmaceuticals, Inc. leads on 12 and Stoke Therapeutics, Inc. on 4.

Valuation

Metric AGIO STOK Biotechnology median
P/E n/m n/m 10.60
P/S 12.39 64.12 9.40
P/B 1.78 5.13 2.13
Price to free cash flow n/m n/m 25.18
EV/EBITDA n/m n/m 0.66
EV/Sales 7.92 52.81 9.02
Earnings yield (21.63%) (14.35%) (32.88%)
Free cash flow yield (19.26%) (11.93%) (23.13%)

Profitability

Metric AGIO STOK Biotechnology median
Gross margin 93.81% 100.00% 68.51%
Operating margin (297.72%) (913.12%) 0.00%
Net margin (264.76%) (862.07%) 0.00%
Free cash flow margin (238.54%) (764.66%) 0.00%
Return on equity (32.95%) (73.62%) (51.96%)
Return on assets (30.44%) (63.42%) (46.06%)
Return on invested capital (75.02%) (482.02%) 0.00%

Growth

Metric AGIO STOK Biotechnology median
Revenue growth (TTM) 214.44% (86.28%) 6.76%
EPS growth (last fiscal year) (161.17%) 92.73% 29.88%
Revenue growth, 5-year CAGR (14.45%) — 9.75%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric AGIO STOK Biotechnology median
Debt to equity 0.00 0.00 0.00
Current ratio 9.69 7.24 4.97
Net debt to EBITDA 1.80 14.29 1.01

Dividend

Metric AGIO STOK Biotechnology median
Dividend yield — — 0.41%
Payout ratio — — —

Size

Metric AGIO STOK Biotechnology median
Market cap 1.69b 1.71b 161.82m

Compare with another peer

Any metric, up to five companies and an Excel export Powerpack