Agios Pharmaceuticals, Inc. (AGIO) vs Mesoblast Limited (MESO)

Agios Pharmaceuticals, Inc. and Mesoblast Limited are both Biotechnology companies. Agios Pharmaceuticals, Inc. and Mesoblast Limited are of similar size ($2.0B and $2.0B). Agios Pharmaceuticals, Inc. grew revenue faster over the last twelve months: 140.6% against −26.5%. Agios Pharmaceuticals, Inc. has the higher net margin (−418.2% vs −1,091.7%) and the lower return on invested capital (−70.2% vs 0.00%). Across the 18 metrics below, Agios Pharmaceuticals, Inc. leads on 9 and Mesoblast Limited on 9.

Valuation

Metric AGIO MESO Biotechnology median
P/E n/m n/m 7.88
P/S 19.71 156.77 11.47
P/B 1.89 2.05 2.52
Price to free cash flow n/m n/m 21.16
EV/EBITDA n/m n/m 0.74
EV/Sales 14.05 156.35 10.73
Earnings yield (21.52%) (7.41%) (28.84%)
Free cash flow yield (18.85%) (8.05%) (23.03%)

Profitability

Metric AGIO MESO Biotechnology median
Gross margin 91.99% (269.72%) 65.16%
Operating margin (466.78%) (826.28%) 0.00%
Net margin (418.24%) (1,091.71%) 0.00%
Free cash flow margin (371.43%) 0.00% 0.00%
Return on equity (34.34%) 0.00% (57.72%)
Return on assets (31.89%) 0.00% (49.22%)
Return on invested capital (70.24%) 0.00% 0.00%

Growth

Metric AGIO MESO Biotechnology median
Revenue growth (TTM) 140.58% (26.54%) 5.64%
EPS growth (last fiscal year) (161.17%) 48.24% —
Revenue growth, 5-year CAGR (14.45%) 74.39% 8.40%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric AGIO MESO Biotechnology median
Debt to equity 0.00 0.22 0.00
Current ratio 10.22 1.58 4.73
Net debt to EBITDA 1.80 (0.67) 0.96

Dividend

Metric AGIO MESO Biotechnology median
Dividend yield — — 2.10%
Payout ratio 0.00 0.00 0.00

Size

Metric AGIO MESO Biotechnology median
Market cap 2.00b 2.01b 162.10m

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