Xenon Pharmaceuticals Inc.

XENE Healthcare Biotechnology

Xenon Pharmaceuticals Inc.’s revenue for fiscal 2025 (year ended December 2025) was $7.5 million, down 20.5% from fiscal 2022.

Revenue
+100.7%
EPS
−3.74%
Free cash flow
−48.6%

Quarter to June 2026, against a year earlier

39.00 1.32 +3.50%
Market cap
$3.7B
P/E
0.0×
Fwd P/E
−8.1×
Dividend yield
—
F-score
n/a
Altman Z
37.76
Beneish M
n/a
Dividend safety
n/a

Xenon Pharmaceuticals Inc. (XENE) Operating margin

Alert me on Operating margin

Xenon Pharmaceuticals Inc.'s operating margin over the twelve months to 30 June 2026 was 0.00%, up 4974.3 percentage points from fiscal 2025 (−4,974.3%). Over the past ten years it has ranged from −10,474.3% (fiscal 2017) to 0.00% (fiscal 2024); the current reading is higher than 18% of that period. That is in line with the Biotechnology industry median of 0.00% and in line with the Healthcare sector median of 0.00%.

Operating margin, annual

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Annual newest first

Period Operating margin Change (points)
FY2025 −4,974.3% (4,974.27)
FY2024 0.00% 0.00
FY2023 0.00% 1,368.91
FY2022 −1,368.9% (940.46)
FY2021 −428.5% (331.14)
FY2020 −97.3% 529.71
FY2019 −627.0% (627.02)
FY2018 0.00% 10,474.28
FY2017 −10,474.3% (9,097.85)
FY2016 −1,376.4% (1,316.33)

Quarterly newest first

Period Operating margin Change (points)
Jun 2026 0.00% 0.00
Mar 2026 0.00% 0.00
Dec 2025 0.00% 0.00
Sep 2025 0.00% 0.00
42 more quarters

Against its own ten years

Low −10,474.3% High 0.00%
Ten-year median −428.5%
Current reading's percentile 18

Operating margin against peers

Company Operating margin
ACAD ACADIA Pharmaceuticals Inc. compare 10.2%
XENE Xenon Pharmaceuticals Inc. 0.00%
IRON Disc Medicine, Inc. compare 0.00%
PBLS Parabilis Medicines, Inc. compare 0.00%
TNGX Tango Therapeutics, Inc. compare 0.00%
VKTX Viking Therapeutics, Inc. compare 0.00%
IOVA Iovance Biotherapeutics, Inc. compare −60.8%
ABCL AbCellera Biologics Inc. compare −340.3%
RLAY Relay Therapeutics, Inc. compare −2,815.5%
Biotechnology industry median 0.00%
Healthcare sector median 0.00%
Market median 0.00%

What Operating margin is

EBIT Margin tells an investor how much operating profit, before interest and taxes, a company keeps from each unit of revenue.

EBIT ÷ Revenue

The full definition of Operating margin →

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