CRISPR Therapeutics AG

CRSP Healthcare Biotechnology

CRISPR Therapeutics AG’s revenue for fiscal 2025 (year ended December 2025) was $3.5 million, down 90.6% from fiscal 2024.

Revenue
+1,325.1%
EPS
+1.55%
Free cash flow
−6.36%

Quarter to September 2026, against a year earlier

49.92 1.36 +2.80%
Market cap
$4.7B
P/E
0.0×
Fwd P/E
−11.8×
Dividend yield
—
F-score
2/9
Altman Z
7.04
Beneish M
n/a
Dividend safety
n/a

CRISPR Therapeutics AG (CRSP) Operating margin

Alert me on Operating margin

CRISPR Therapeutics AG's operating margin over the twelve months to 30 September 2026 was −2,114.8%, up 16818.9 percentage points from fiscal 2025 (−18,933.7%). Over the past ten years it has ranged from −56,190.4% (fiscal 2022) to 40.8% (fiscal 2021); the current reading is higher than 27% of that period. That is below the Biotechnology industry median of 0.00% and below the Healthcare sector median of 0.00%.

Operating margin, annual

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Annual newest first

Period Operating margin Change (points)
FY2025 −18,933.7% (17,683.27)
FY2024 −1,250.4% (1,190.43)
FY2023 −60.0% 56,130.45
FY2022 −56,190.4% (56,231.22)
FY2021 40.8% 49,336.37
FY2020 −49,295.6% (49,311.69)
FY2019 16.1% 5,103.94
FY2018 −5,087.8% (4,930.11)
FY2017 −157.7% 1,161.64
FY2016 −1,319.3% 9,097.27

Quarterly newest first

Period Operating margin Change (points)
Sep 2026 −1,026.5% 125.36
Jun 2026 −1,151.8% 7,781.49
Mar 2026 −8,933.3% 8,979.17
Dec 2025 −17,912.5% (3,057.72)
40 more quarters

Against its own ten years

Low −56,190.4% High 40.8%
Ten-year median −1,319.3%
Current reading's percentile 31

Operating margin against peers

Company Operating margin
COGT Cogent Biosciences, Inc. compare 0.00%
MANE Veradermics Incorporated compare 0.00%
ERAS Erasca, Inc. compare 0.00%
DFTX Definium Therapeutics, Inc. compare 0.00%
EWTX Edgewise Therapeutics, Inc. compare 0.00%
LEGN Legend Biotech Corporation Sponsored ADR compare −5.06%
TVTX Travere Therapeutics, Inc. compare −20.5%
CRSP CRISPR Therapeutics AG −2,114.8%
DNTH Dianthus Therapeutics, Inc. compare −8,683.9%
Biotechnology industry median 0.00%
Healthcare sector median 0.00%
Market median 0.00%

What Operating margin is

EBIT Margin tells an investor how much operating profit, before interest and taxes, a company keeps from each unit of revenue.

EBIT ÷ Revenue

The full definition of Operating margin →

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