Twist Bioscience Corporation

TWST Healthcare Biotechnology

Twist Bioscience Corporation’s revenue for fiscal 2025 (year ended September 2025) was $376.6 million, up 20.3% from fiscal 2024.

Revenue
+23.2%
EPS
−264.7%
Free cash flow
−7.23%
Total debt
0.00%

Quarter to June 2026, against a year earlier

120.82 0.21 +0.17%
Market cap
$7.9B
P/E
0.0×
Fwd P/E
−91.4×
Dividend yield
—
F-score
4/9
Altman Z
3.44
Beneish M
−2.30
Dividend safety
n/a

Twist Bioscience Corporation (TWST) Return on invested capital

Alert me on Return on invested capital

Twist Bioscience Corporation's return on invested capital over the twelve months to 30 June 2026 was −30.8%, up 2.5 percentage points from fiscal 2025 (−33.3%). Over the past ten years it has ranged from −313.4% (fiscal 2019) to 0.00% (fiscal 2016); the current reading is higher than 90% of that period. That is below the Biotechnology industry median of 0.00% and below the Healthcare sector median of 0.00%.

Return on invested capital, annual

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Annual newest first

Period Return on invested capital Change (points)
FY2025 −33.3% 36.98
FY2024 −70.3% (33.25)
FY2023 −37.1% 3.07
FY2022 −40.1% 20.41
FY2021 −60.5% 111.14
FY2020 −171.7% 141.71
FY2019 −313.4% (68.69)
FY2018 −244.7% 31.68
FY2017 −276.4% (276.38)
FY2016 0.00% —

Against its own ten years

Low −313.4% High 0.00%
Ten-year median −65.4%
Current reading's percentile 90

Return on invested capital against peers

Company Return on invested capital
PTGX Protagonist Therapeutics, Inc. compare 61.8%
KRYS Krystal Biotech, Inc. compare 27.2%
CAI Caris Life Sciences,�Inc. compare 22.2%
TGTX TG Therapeutics, Inc. compare 10.7%
IBRX ImmunityBio, Inc. compare 0.00%
CYTK Cytokinetics, Incorporated compare 0.00%
SYRE Spyre Therapeutics, Inc. compare 0.00%
TWST Twist Bioscience Corporation −30.8%
MDGL Madrigal Pharmaceuticals, Inc. compare −1,480.3%
Biotechnology industry median 0.00%
Healthcare sector median 0.00%
Market median 0.00%

What Return on invested capital is

Return on Invested Capital shows how much after-tax operating profit a company earns on the money its lenders and shareholders have put in.

TTM: (Operating Income × 0.625) ÷ (Shareholders Equity (Total) (latest quarter) + Long Term Debt (Total) (latest quarter) + Current Part of Debt (latest quarter) − Cash & Short Term Investments (latest quarter)); Annual: (Operating Income × 0.625) ÷ (Shareholders Equity (Total) + Long Term Debt (Total) + Current Part of Debt − Cash & Short Term Investments)

The full definition of Return on invested capital →

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