Mirum Pharmaceuticals, Inc.

MIRM Healthcare Biotechnology

Mirum Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $521.3 million, up 54.7% from fiscal 2024.

Revenue
+39.6%
EPS
−1,136.8%
Free cash flow
−114.2%
Total debt
+136.4%

Quarter to September 2026, against a year earlier

93.82 0.28 +0.30%
Market cap
$6.1B
P/E
0.0×
Fwd P/E
−5.6×
Dividend yield
—
F-score
6/9
Altman Z
4.42
Beneish M
−2.46
Dividend safety
n/a

Mirum Pharmaceuticals, Inc. (MIRM) Operating margin

Alert me on Operating margin

Mirum Pharmaceuticals, Inc.'s operating margin over the twelve months to 30 September 2026 was −133.6%, down 129.4 percentage points from fiscal 2025 (−4.25%). Over the past ten years it has ranged from −906.1% (fiscal 2021) to 0.00% (fiscal 2020); the current reading is higher than 63% of that period. That is below the Biotechnology industry median of 0.00% and below the Healthcare sector median of 0.00%.

Operating margin, annual

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Annual newest first

Period Operating margin Change (points)
FY2025 −4.25% 21.75
FY2024 −26.0% 32.57
FY2023 −58.6% 111.71
FY2022 −170.3% 735.84
FY2021 −906.1% (906.12)
FY2020 0.00% 0.00
FY2019 0.00% 0.00
FY2018 0.00% —

Quarterly newest first

Period Operating margin Change (points)
Sep 2026 −32.2% (8.03)
Jun 2026 −24.1% 469.64
Mar 2026 −493.8% (490.71)
Dec 2025 −3.07% (5.03)
28 more quarters

Against its own ten years

Low −906.1% High 0.00%
Ten-year median −15.1%
Current reading's percentile 37

Operating margin against peers

Company Operating margin
PTCT PTC Therapeutics, Inc. compare 12.8%
LGND Ligand Pharmaceuticals Incorporated compare 9.29%
KOD Kodiak Sciences Inc. compare 0.00%
ORKA Oruka Therapeutics, Inc. compare 0.00%
IMVT Immunovant, Inc. compare 0.00%
BLTE Belite Bio, Inc. Sponsored ADR compare 0.00%
IONS Ionis Pharmaceuticals, Inc. compare −68.0%
MIRM Mirum Pharmaceuticals, Inc. −133.6%
CGON CG Oncology, Inc. compare −4,056.2%
Biotechnology industry median 0.00%
Healthcare sector median 0.00%
Market median 0.00%

What Operating margin is

EBIT Margin tells an investor how much operating profit, before interest and taxes, a company keeps from each unit of revenue.

EBIT ÷ Revenue

The full definition of Operating margin →

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