Syndax Pharmaceuticals, Inc.

SNDX Healthcare Biotechnology

Syndax Pharmaceuticals, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $172.4 million, up 627.8% from fiscal 2024. In the quarter to June 2026, revenue grew 91.8%, EPS grew 33.7%, free cash flow grew 65.5% and total debt rose 71.0%, each against the same quarter a year earlier.

12.90 0.75 −5.49%
Market cap
$1.2B
P/E
0.0×
Fwd P/E
−10.1×
Dividend yield
—
F-score
n/a
Altman Z
−2.09
Beneish M
3.29
Dividend safety
n/a
Dec '16 Dec '17 Dec '18 Dec '19 Dec '20 Dec '21 Dec '22 Dec '23 Dec '24 Dec '25
P/E ratio
0.00 0.00 0.00 0.00 0.00 50.91 — — 0.00 0.00
Piotroski F-Score
— 3 2 2 3 7 — — — —
Altman Z-Score
(1.63) (0.82) (7.14) (8.02) 9.07 16.51 — — (1.49) (2.09)
P/S ratio
87.72 87.35 74.43 176.47 605.60 8.16 — — 7.53 10.56
Altman Z″-Score (non-manufacturers)
(2.37) (2.78) (16.08) (25.93) 3.82 13.07 — — (3.43) (7.54)
P/FCF ratio
0.00 0.00 0.00 0.00 0.00 0.00 — — 0.00 0.00
P/Operating CF
(10.27) (14.47) (7.51) (21.03) (58.77) 11.32 — — (19.72) (26.19)
Beneish M-Score
— 1.47 (3.76) (1.72) (2.18) 77.70 — — — 3.29
P/B ratio
1.27 1.77 2.13 8.47 3.64 2.79 — — 3.93 28.16
EV/Sales
12.63 32.23 30.17 137.66 425.60 5.10 — — 5.94 10.29
EV/EBITDA
0.00 0.00 0.00 0.00 0.00 26.50 — — 0.00 0.00
EV/FCF
(0.43) (1.43) (0.67) (4.11) (9.04) (7.31) — — (2.03) (5.49)
Current Ratio
10.47 8.45 5.18 3.39 15.84 21.68 16.85 10.00 5.82 4.40
Net Debt/EBITDA
2.41 2.11 1.06 1.01 3.82 (15.87) 3.12 2.36 0.68 0.25
Debt/Equity
0.00 0.00 0.00 0.03 0.08 0.05 0.00 0.00 1.19 5.32
ROE
53.64% (64.53%) (94.00%) (132.43%) (54.31%) 7.55% (34.10%) (40.98%) (75.69%) (161.82%)
ROA
(47.33%) (49.39%) (66.90%) (76.02%) (42.33%) 6.64% (31.54%) (37.72%) (47.66%) (45.50%)
ROIC
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% (434.21%) 0.00%
Return on Tangible Assets
(47.83%) (51.57%) (109.39%) (126.68%) (27.50%) 5.82% (32.41%) (40.05%) (63.81%) (69.93%)
Average Days of Receivables
91.55 65.28 60.87 27.91 42.11 1.12 0.00 — 173.21 144.31
Earnings Yield
(64.89%) (32.95%) (65.39%) (21.07%) (8.45%) 1.96% — — (28.21%) (15.66%)
Free Cash Flow Yield
(33.10%) (25.80%) (60.86%) (18.98%) (7.78%) (8.56%) — — (38.82%) (17.74%)
Free Cash Flow per Share
(2.42) (2.26) (2.71) (1.66) (1.73) 0.56 (2.20) (2.28) (3.21) (3.73)
Book value per Share
5.76 4.97 2.09 1.04 6.11 7.84 7.69 7.88 3.37 0.75
Free Cash Flow
(35.42) (47.45) (68.72) (50.61) (71.26) 29.00 (133.45) (160.60) (274.90) (323.17)
EV/EBIT
0.00 0.00 0.00 0.00 0.00 27.19 — — 0.00 0.00
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