Prothena Corporation plc

PRTA Healthcare Biotechnology

Prothena Corporation plc’s revenue for fiscal 2025 (year ended December 2025) was $9.7 million, down 92.8% from fiscal 2024.

Revenue
−77.2%
EPS
+84.6%
Free cash flow
+44.6%

Quarter to June 2026, against a year earlier

8.38 0.17 +2.07%
Market cap
$421.5M
P/E
0.0×
Fwd P/E
71.4×
Dividend yield
—
F-score
2/9
Altman Z
−0.24
Beneish M
n/a
Dividend safety
n/a
Dec '16 Dec '17 Dec '18 Dec '19 Dec '20 Dec '21 Dec '22 Dec '23 Dec '24 Dec '25
Piotroski F-Score
2 5 4 3 3 7 2 3 3 2
P/E ratio
0.00 0.00 0.00 0.00 0.00 35.54 0.00 0.00 0.00 0.00
P/S ratio
1,621.17 51.72 426.66 775.59 561.99 10.89 47.01 22.45 5.51 53.08
Altman Z-Score
9.61 8.22 (0.33) 0.70 (1.49) 9.31 11.61 6.85 4.88 (0.24)
P/FCF ratio
0.00 0.00 0.00 0.00 0.00 23.74 0.00 0.00 0.00 0.00
Altman Z″-Score (non-manufacturers)
4.67 4.93 1.36 1.00 (3.26) 6.31 5.84 3.42 5.27 (5.98)
P/Operating CF
(50.59) (36.01) (19.17) (43.58) (25.11) (97.29) (509.29) (40.18) (15.59) (22.05)
Beneish M-Score
(3.14) 19.06 (9.25) 33.47 (3.87) — — — — —
P/B ratio
4.68 3.50 1.26 2.31 2.61 4.69 4.07 3.65 1.53 1.83
EV/Sales
1,254.42 36.55 (21.15) 314.02 214.12 8.01 33.83 15.66 2.02 21.33
EV/EBITDA
0.00 0.00 0.13 0.00 0.00 20.38 0.00 0.00 0.00 0.00
EV/FCF
(9.96) (7.47) 0.67 (4.78) (2.27) 17.45 (16.69) (10.47) (1.82) (1.26)
Current Ratio
9.53 11.41 28.90 21.36 11.58 17.48 14.34 11.24 10.01 7.72
Net Debt/EBITDA
2.46 2.74 2.75 4.76 2.81 (7.35) 5.69 3.40 3.12 1.46
Debt/Equity
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
ROE
(44.10%) (39.67%) (42.63%) (26.07%) (48.65%) 20.61% (21.50%) (24.85%) (23.34%) (63.62%)
ROA
(37.89%) (32.05%) (31.28%) (16.92%) (29.55%) 14.21% (17.11%) (20.22%) (19.67%) (55.86%)
ROIC
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% (621.71%) 0.00%
Return on Tangible Assets
(39.36%) (34.52%) (33.17%) (21.31%) (40.27%) 12.10% (17.44%) (25.08%) (27.80%) (88.28%)
Average Days of Receivables
61.58 3.18 0.76 30.49 6.42 0.00 0.00 20.61 0.00 0.00
Earnings Yield
(9.36%) (10.74%) (38.25%) (12.32%) (23.23%) 2.81% (4.67%) (7.19%) (16.46%) (47.54%)
Free Cash Flow Yield
(7.77%) (9.46%) (7.36%) (8.48%) (16.80%) 4.21% (4.31%) (6.66%) (20.19%) (31.85%)
Free Cash Flow per Share
(3.87) (3.58) (0.76) (1.34) (2.02) 2.08 (2.31) (2.57) (2.80) (3.04)
Book value per Share
10.64 10.81 8.17 6.84 4.61 10.54 13.13 10.55 9.06 5.21
Free Cash Flow
(132.89) (134.70) (30.00) (53.52) (80.56) 92.03 (109.28) (136.68) (150.35) (163.72)
EV/EBIT
0.00 0.00 0.13 0.00 0.00 22.31 0.00 0.00 0.00 0.00
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