Prothena Corporation plc

PRTA Healthcare Biotechnology

Prothena Corporation plc’s revenue for fiscal 2025 (year ended December 2025) was $9.7 million, down 92.8% from fiscal 2024. In the quarter to June 2026, revenue fell 77.2%, EPS grew 84.6% and free cash flow grew 44.6%, each against the same quarter a year earlier. Insiders bought in the last twelve months.

8.42 0.01 −0.12%
Market cap
$432.8M
P/E
0.0×
Fwd P/E
188×
Dividend yield
—
F-score
2/9
Altman Z
−0.24
Beneish M
n/a
Dividend safety
n/a
Dec '16 Dec '17 Dec '18 Dec '19 Dec '20 Dec '21 Dec '22 Dec '23 Dec '24 Dec '25
Piotroski F-Score
2 5 4 3 3 7 2 3 3 2
P/E ratio
0.00 0.00 0.00 0.00 0.00 35.54 0.00 0.00 0.00 0.00
P/S ratio
1,621.17 51.72 426.66 775.59 561.99 10.89 47.01 22.45 5.51 53.08
Altman Z-Score
9.61 8.22 (0.33) 0.70 (1.49) 9.31 11.61 6.85 4.88 (0.24)
P/FCF ratio
0.00 0.00 0.00 0.00 0.00 23.74 0.00 0.00 0.00 0.00
Altman Z″-Score (non-manufacturers)
4.67 4.93 1.36 1.00 (3.26) 6.31 5.84 3.42 5.27 (5.98)
P/Operating CF
(50.59) (36.01) (19.17) (43.58) (25.11) (97.29) (509.29) (40.18) (15.59) (22.05)
Beneish M-Score
(3.14) 19.06 (9.25) 33.47 (3.87) — — — — —
P/B ratio
4.68 3.50 1.26 2.31 2.61 4.69 4.07 3.65 1.53 1.83
Price to Tangible BV
4.68 3.50 1.26 2.31 2.61 4.69 4.07 3.65 1.53 1.83
EV/Sales
1,254.42 36.55 (21.15) 314.02 214.12 8.01 33.83 15.66 2.02 21.33
EV/EBITDA
0.00 0.00 0.13 0.00 0.00 20.38 0.00 0.00 0.00 0.00
EV/Operating CF
(11.38) (7.67) 0.71 (4.83) (2.27) 17.34 (16.76) (10.68) (1.82) (1.26)
EV/FCF
(9.96) (7.47) 0.67 (4.78) (2.27) 17.45 (16.69) (10.47) (1.82) (1.26)
Quick Ratio
9.42 11.18 28.65 21.21 11.48 17.31 14.17 10.99 9.72 7.53
Current Ratio
9.53 11.41 28.90 21.36 11.58 17.48 14.34 11.24 10.01 7.72
Net Debt/EBITDA
2.46 2.74 2.75 4.76 2.81 (7.35) 5.69 3.40 3.12 1.46
Debt/Assets
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
Debt/Equity
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Asset Turnover
0.00 0.06 0.00 0.00 0.00 0.43 0.08 0.13 0.22 0.02
Operating CF/Net income
0.73 0.86 0.18 0.68 0.72 1.38 0.93 0.91 1.23 0.67
Capex/Depreciation
(6.86) (1.15) (0.54) (0.08) (0.03) (0.08) (0.07) (0.33) (0.08) (0.04)
ROE
(44.10%) (39.67%) (42.63%) (26.07%) (48.65%) 20.61% (21.50%) (24.85%) (23.34%) (63.62%)
ROA
(37.89%) (32.05%) (31.28%) (16.92%) (29.55%) 14.21% (17.11%) (20.22%) (19.67%) (55.86%)
ROIC
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% (621.71%) 0.00%
Return on Tangible Assets
(39.36%) (34.52%) (33.17%) (21.31%) (40.27%) 12.10% (17.44%) (25.08%) (27.80%) (88.28%)
Average Days of Receivables
61.58 3.18 0.76 30.49 6.42 0.00 0.00 20.61 0.00 0.00
Research and Development Expense of Revenue
11,330.24% 488.92% 10,595.08% 6,245.21% 8,778.90% 41.02% 251.48% 241.40% 164.64% 1,392.52%
Selling, General and Administrative Expense of Revenue
3,891.56% 175.25% 4,448.38% 4,390.17% 4,537.28% 23.09% 92.57% 67.68% 49.72% 613.30%
Intangible Assets out of Total Assets
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Share Based Compensation of Revenue
2,362.94% 97.26% 2,729.01% 2,897.42% 2,580.77% 12.29% 58.11% 44.78% 34.01% 388.68%
Graham Net Nets
0.17 0.24 0.63 0.37 0.31 0.20 0.23 0.25 0.57 0.52
Graham Number
0.00 0.00 0.00 0.00 0.00 18.15 0.00 0.00 0.00 0.00
Earnings Yield
(9.36%) (10.74%) (38.25%) (12.32%) (23.23%) 2.81% (4.67%) (7.19%) (16.46%) (47.54%)
Free Cash Flow Yield
(7.77%) (9.46%) (7.36%) (8.48%) (16.80%) 4.21% (4.31%) (6.66%) (20.19%) (31.85%)
Revenue per Share
0.03 0.73 0.02 0.02 0.02 4.54 1.14 1.72 2.51 0.18
Operating CF per Share
(3.38) (3.48) (0.71) (1.33) (2.01) 2.09 (2.30) (2.52) (2.79) (3.04)
Capex per Share
(0.48) (0.09) (0.04) (0.01) 0.00 (0.01) (0.01) (0.05) (0.01) 0.00
Free Cash Flow per Share
(3.87) (3.58) (0.76) (1.34) (2.02) 2.08 (2.31) (2.57) (2.80) (3.04)
Cash per Share
11.26 11.09 10.81 9.42 7.43 13.09 15.00 11.65 8.77 5.71
Shareholders Equity per Share
10.64 10.81 8.17 6.84 4.61 10.54 13.13 10.55 9.06 5.21
Interest Debt per Share
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Book value per Share
10.64 10.81 8.17 6.84 4.61 10.54 13.13 10.55 9.06 5.21
Free Cash Flow
(132.89) (134.70) (30.00) (53.52) (80.56) 92.03 (109.28) (136.68) (150.35) (163.72)
Working Capital
350.29 388.96 416.46 360.66 273.44 551.36 668.95 582.39 436.91 274.35
Capital Expenditures
(16.64) (3.52) (1.73) (0.55) (0.20) (0.57) (0.46) (2.77) (0.30) (0.14)
Net Current Asset Value
296.79 337.19 255.59 232.03 150.32 441.49 583.11 504.27 425.23 268.86
EV/EBIT
0.00 0.00 0.13 0.00 0.00 22.31 0.00 0.00 0.00 0.00
Capex to Sales
15.78 0.13 1.81 0.67 0.23 0.00 0.01 0.03 0.00 0.01
Price to Operating Income
0.00 0.00 0.00 0.00 0.00 30.36 0.00 0.00 0.00 0.00
Other line items
Depreciation/Fixed assets
0.04 0.06 0.06 1.76 2.74 3.38 3.89 2.19 1.16 1.73
Cash ROIC
(17.66%) (16.33%) (4.00%) (8.25%) (16.76%) 8.81% (8.20%) (11.57%) (15.69%) (27.84%)
Accounts Receivable Turnover
3.07 131.67 7.89 23.26 20.55 0.00 0.00 35.32 0.00 0.00
Accounts Payable Turnover
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Inventory Turnover
— — — — — — 0.00 — — —
Average Days of Payables
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Days of Inventory on Hand
— — — — — — 0.00 — — —
Average Receivables
0.34 0.21 0.12 0.04 0.04 — — 2.59 — —
Average Payables
8.79 13.35 7.55 1.36 2.68 3.90 6.48 17.33 16.58 6.82
Average Assets
422.61 478.15 497.56 459.03 376.12 471.17 683.70 727.21 621.75 436.96
Average Common Equity
363.04 386.30 365.09 297.96 228.46 325.02 544.04 591.70 524.15 383.70

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