Saturday 7 November 2026
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Seres Therapeutics, Inc.
MCRB Healthcare Biotechnology
Seres Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $789,000.00, down 99.4% from fiscal 2023.
- Revenue
- +69.0%
- EPS
- −273.6%
- Free cash flow
- −576.7%
Quarter to September 2026, against a year earlier
1.97
0.12
−5.74%
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Analyst price targets
Free accountTen years at a glance Fiscal years to December
| Ten-year view | Analyst estimates Powerpack | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Group | Line | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | TTM Sep ’26 | Trend | 10 yrs | 2026e | 2027e | 2028e | Next 3/yr |
| Income, $m | ||||||||||||||||||
| Income, $m | Revenue | 22 | 32 | 28 | 35 | 33 | 145 | 7 | 126 | — | 1 | 2 | (30.8%) | 14 | 0 | 0 | (29.8%) | |
| Gross margin, % | 100.00 | 100.00 | 100.00 | 100.00 | 100.00 | 100.00 | 100.00 | 100.00 | — | 100.00 | 100.00 | 0.0 pt | ||||||
| EBT | (92) | (89) | (99) | (70) | (89) | (66) | (184) | (190) | (126) | 6 | (47) | n/m | ||||||
| EBT margin, % | (420.74) | (278.44) | (350.03) | (203.68) | (268.33) | (45.25) | (2,575.49) | (150.51) | 0.00 | 721.93 | (2,209.55) | +1,142.7 pt | ||||||
| Net income | (92) | (89) | (99) | (70) | (89) | (66) | (250) | (114) | 0 | 6 | (47) | n/m | ||||||
| Per share, $ | ||||||||||||||||||
| Per share, $ | Revenue | 10.92 | 15.87 | 13.88 | 12.18 | 8.33 | 31.61 | 1.32 | 19.74 | 0.00 | 0.09 | 0.21 | (41.4%) | |||||
| Earnings | (46.00) | (44.20) | (48.60) | (24.80) | (22.40) | (14.40) | (46.20) | (17.80) | 0.00 | 0.64 | (5.00) | n/m | ||||||
| Cash flow | 22.04 | (37.34) | (30.85) | (27.01) | (23.46) | 1.46 | (42.34) | (18.34) | (19.13) | 0.13 | (6.41) | (43.7%) | ||||||
| Capex | (10.79) | (2.31) | (0.95) | (0.35) | (0.15) | (2.09) | (1.82) | (1.25) | (0.05) | 0.00 | 0.02 | (57.7%) | ||||||
| Free cash flow | 11.26 | (39.65) | (31.80) | (27.37) | (23.61) | (0.63) | (44.16) | (19.58) | (19.17) | 0.12 | (6.38) | (39.6%) | ||||||
| Book value | 66.57 | 30.01 | (23.58) | (17.06) | 43.80 | 28.68 | 2.00 | (7.01) | 1.77 | 4.99 | 2.14 | (25.0%) | ||||||
| Shares, m | 2 | 2 | 2 | 3 | 4 | 5 | 5 | 6 | 8 | 9 | 10 | +18.0% | ||||||
| Valuation, × | ||||||||||||||||||
| Valuation, × | P/E | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | — | 22.21 | 0.00 | 2.5 | |||||
| P/S | 18.33 | 13.29 | 6.52 | 5.66 | 58.85 | 5.27 | 81.88 | 1.42 | — | 89.49 | 9.25 | 31.2 | ||||||
| P/B | 3.01 | 7.03 | 0.00 | 0.00 | 11.19 | 5.81 | 54.12 | 0.00 | — | 2.98 | 0.92 | 9.3 | ||||||
| EV/Sales | 9.94 | 8.90 | 3.72 | 3.63 | 51.96 | 3.44 | 63.53 | 1.21 | — | 128.00 | 49.24 | 30.5 | ||||||
| EV/FCF | 9.65 | (3.56) | (1.62) | (1.62) | (18.32) | (172.98) | (1.90) | (1.22) | — | 175.40 | (1.64) | (1.8) | ||||||
| Cash, $m | ||||||||||||||||||
| Cash, $m | Operating cash flow | 44 | (76) | (63) | (77) | (94) | 7 | (229) | (117) | (149) | 1 | (64) | (33.5%) | |||||
| Capex | (21) | (5) | (2) | (1) | (1) | (10) | (10) | (8) | 0 | 0 | 0 | (50.0%) | ||||||
| Free cash flow | 22 | (80) | (65) | (78) | (94) | (3) | (239) | (125) | (149) | 1 | (64) | (28.6%) | ||||||
| Balance, $m | ||||||||||||||||||
| Balance, $m | Working capital | 168 | 123 | 51 | 54 | 222 | 221 | 109 | 77 | (3) | 30 | 14 | (17.4%) | |||||
| Net debt | (183) | (141) | (79) | (70) | (229) | (266) | (131) | (26) | (31) | (46) | (18) | (14.2%) | ||||||
| Shareholders’ equity | 133 | 61 | (48) | (48) | 175 | 132 | 11 | (45) | 14 | 44 | 21 | (11.5%) | ||||||
| Returns, % | ||||||||||||||||||
| Returns, % | ROA | (37.41) | (38.68) | (63.83) | (55.58) | (37.50) | (18.80) | (71.10) | (32.15) | 0.05 | 4.10 | (44.85) | +41.5 pt | |||||
| ROIC | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | (1,267.77) | 0.0 pt | ||||||
| ROE | (54.18) | (92.46) | (1,563.81) | 145.85 | (140.99) | (42.83) | (351.62) | 667.53 | (0.88) | 19.64 | (144.35) | +73.8 pt | ||||||
| People | ||||||||||||||||||
| People | Employees | 127 | 138 | 145 | 108 | 155 | 333 | 431 | 160 | 103 | 66 | — | (7.0%) | |||||
| Revenue/emp, $m | 0.17 | 0.23 | 0.19 | 0.32 | 0.21 | 0.44 | 0.02 | 0.79 | 0.00 | 0.01 | — | (25.6%) | ||||||
Negative figures in brackets.
estimates
Fiscal years to Dec 2025 · latest quarter Sep 2026 · fundamentals updated 6 Nov 2026
Seres Therapeutics, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier
| Company | Market cap | P/E | Fwd P/E | Revenue growth (Q) | EPS growth (Q) | FCF growth (Q) | Gross margin (Q) | EBIT margin (Q) | Compare |
|---|---|---|---|---|---|---|---|---|---|
| EVAX Evaxion A/S - Sponsored ADR | $23.0M | — (loss-making) | — (loss-making) | +14,590.20% (above 0%: growing) | n/m | −56.70% (below 0%: shrinking) | 100.00% | 0.00% | Compare |
| IGC IGC Pharma, Inc. | $22.0M | — (loss-making) | — (loss-making) | 0.00% | n/m | −45.33% (below 0%: shrinking) | 18.60% | (588.72%) | Compare |
| CRVO CervoMed Inc. | $21.9M | — (loss-making) | — (loss-making) | −99.60% (below 0%: shrinking) | n/m | −6.20% (below 0%: shrinking) | 100.00% | 0.00% | Compare |
| FLNA Cassava Sciences, Inc. | $21.8M | — (loss-making) | — | +1,328.04% (above 0%: growing) | n/m | +21.65% (above 0%: growing) | 0.00% | 0.00% | Compare |
| MCRB Seres Therapeutics, Inc. | $20.8M | — (loss-making) | — (loss-making) | +68.95% (above 0%: growing) | n/m | −576.66% (below 0%: shrinking) | 100.00% | (2,723.78%) | |
| ATOS Atossa Therapeutics, Inc. | $20.2M | — (loss-making) | — | −94.28% (below 0%: shrinking) | n/m | −32.86% (below 0%: shrinking) | 0.00% | 0.00% | Compare |
| IMMP Prima BioMed Ltd | $19.8M | — | — | — | n/m | −589,653.13% (below 0%: shrinking) | 100.00% | (101.89%) | Compare |
| BSEM BioStem Technologies, Inc. | $19.4M | — (loss-making) | — (loss-making) | −27.95% (below 0%: shrinking) | n/m | — | 61.28% | (106.35%) | Compare |
| COCP Cocrystal Pharma, Inc. | $19.3M | — (loss-making) | — (loss-making) | −81.05% (below 0%: shrinking) | n/m | −16.75% (below 0%: shrinking) | 100.00% | (3,032.38%) | Compare |
| Median of peers | $21.0M | — | — | −27.95% | — | −32.86% | 80.64% | (50.94%) |
Pay and ownership Proxy statement filed 27 April 2026
Ownership
Directors and executive officers, together
5.20%
Entities affiliated with Flagship Pioneering
12.00%
Nestlé S.A.
11.30%
Ownership is the proxy’s own table: the directors and officers as a group, and every holder of 5% or more.
Read the proxy statement