Seres Therapeutics, Inc. MCRB

3.52 (0.10) (2.76%) as of 25 Sep
Market cap
$36.0M
P/E
0.0×

Insider Decisions

Total sells 0.05
in millions of $
Nov 25 Feb 26 May 26 Aug 26
Buy — — — — — — — — — — — —
Sell — 4 — — 4 — — 4 — — 4 —
Insider Ownership 22.32%

Capital & Financial Ratios

Market Cap 35.99
Revenue 1.88
Net Income (22.46)
Free Cash Flow (51.25)
Net Debt (15.59)
Current Ratio 2.11
Debt/Equity 0.00
P/E ratio 0.00
P/S ratio 18.14
P/B ratio 0.99
Past 5Y EPS Growth 5.33%
This Y EPS Growth (649.09%)
Next Y EPS Growth (40.71%)
Next 5Y EPS Growth 25.41%
in millions of $

Dividends

Payout Ratio 0.00
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2025 Powerpack
2024 Powerpack
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
2017 Powerpack
predictions in italic, special payouts not included in total or ratios

Assets vs Liabilities

2023 2024 2025 Q'26
Cash 128 31 46 16
Receivables 9 2 1 25
Inventory — — — —
Other — — — —
175 39 49 42
2023 2024 2025 Q'26
Payables 4 4 2 1
ST’ Debt — — — —
Other — — — —
99 41 19 20
in millions of $

Compound Annual Growth

10y 5y 3y
Sales — (53.03%) (82.41%)
Cash Flow 0.00% 0.00% 0.00%
Earnings 0.00% 0.00% 0.00%
Book Value (14.24%) (24.03%) 60.06%

Revenue

Mar Jun Sep Dec Year
’26 0 1 — — —
’25 — — 0 0 1
’23 — 126 0 0 126
’22 1 1 3 1 7
’21 6 5 127 7 145
’20 8 6 1 18 33
’19 7 13 7 8 35
in millions of $ · fiscal quarters ending in the months shown
value withheld pending a data check

Operating Cash Flow

Mar Jun Sep Dec Year
’26 (16) (22) — — —
’25 27 (13) 2 (15) 1
’24 (35) (40) (35) (39) (149)
’23 (77) 66 (59) (47) (117)
’22 (66) (50) (60) (53) (229)
’21 (29) (40) 128 (52) 7
’20 (24) (26) (26) (18) (94)
in millions of $ · fiscal quarters ending in the months shown

Free Cash Flow

Mar Jun Sep Dec Year
’26 (16) (22) — — —
’25 27 (13) 2 (15) 1
’24 (35) (40) (35) (39) (149)
’23 (81) 65 (61) (48) (125)
’22 (69) (52) (61) (56) (239)
’21 (31) (42) 124 (53) (3)
’20 (24) (26) (26) (18) (94)
in millions of $ · fiscal quarters ending in the months shown

EPS

Mar Jun Sep Dec Year
’26 (2.08) 0.47 — — —
’25 3.75 (2.27) 0.94 (1.76) 0.64
’24 (5.40) (4.40) 11.60 (1.78) 0.00
’23 (11.40) 7.20 (7.40) (6.40) (17.80)
’22 (12.20) (14.00) (9.80) (10.80) (46.20)
’21 (7.80) (10.60) 14.40 (11.00) (14.40)
’20 (5.60) (5.60) (7.20) (3.60) (22.40)
fiscal quarters ending in the months shown

Target Price Range

Analyst price targets

Recommendation Rating

1
1Buy 2 3Hold 4 5Sell
2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 2027 2028
161.00 177.00 90.40 40.40 50.40 108.20 50.00 18.20 10.80 6.53

Analyst estimates 2026–2028

Powerpack
Low Price
719.60 348.40 226.90 167.80 770.00 598.00 189.80 137.40 41.00 29.98
High Price
127 138 145 108 155 333 431 160 103 66
Employees
0 0 0 0 0 0 0 1 0 0
Revenue/Emp
22 32 28 35 33 145 7 126 — 1
Revenue
100.00% 100.00% 100.00% 100.00% 100.00% 100.00% 100.00% 100.00% — 100.00%
Gross Margin
(92) (89) (99) (70) (89) (66) (184) (190) (126) 6
EBT
(420.74%) (278.44%) (350.03%) (203.68%) (268.33%) (45.25%) (2,575.49%) (150.51%) 0.00% 721.93%
EBT Margin
(92) (89) (99) (70) (89) (66) (250) (114) 0 6
Net Income
4 7 8 8 8 9 8 7 7 4
Depreciation
10.92 15.87 13.88 12.18 8.33 31.61 1.32 19.74 0.00 0.09
Revenue/Sh
(46.00) (44.20) (48.60) (24.80) (22.40) (14.40) (46.20) (17.80) 0.00 0.64
Earnings/Sh
22.04 (37.34) (30.85) (27.01) (23.46) 1.46 (42.34) (18.34) (19.13) 0.13
Cash Flow/Sh
(10.79) (2.31) (0.95) (0.35) (0.15) (2.09) (1.82) (1.25) (0.05) 0.00
Capex/Sh
11.26 (39.65) (31.80) (27.37) (23.61) (0.63) (44.16) (19.58) (19.17) 0.12
Free CF/Sh
66.57 30.01 (23.58) (17.06) 43.80 28.68 2.00 (7.01) 1.77 4.99
Book Value/Sh
2 2 2 3 4 5 5 6 8 9
Shares
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 — 22.21
PE Ratio
18.33 13.29 6.52 5.66 58.85 5.27 81.88 1.42 — 89.49
PS Ratio
3.01 7.03 0.00 0.00 11.19 5.81 54.12 0.00 — 2.98
PB Ratio
9.94 8.90 3.72 3.63 51.96 3.44 63.53 1.21 — 128.00
EV/Sales
9.65 (3.56) (1.62) (1.62) (18.32) (172.98) (1.90) (1.22) — 175.40
EV/FCF
44 (76) (63) (77) (94) 7 (229) (117) (149) 1
Op' Cash Flow
(21) (5) (2) (1) (1) (10) (10) (8) 0 0
Capex
22 (80) (65) (78) (94) (3) (239) (125) (149) 1
FCF
168 123 51 54 222 221 109 77 (3) 30
Working Cap'
11 9 7 25 25 25 51 102 — —
Total Debt
(183) (141) (79) (70) (229) (266) (131) (26) (31) (46)
Net Debt
133 61 (48) (48) 175 132 11 (45) 14 44
Sh' Equity
(37.41%) (38.68%) (63.83%) (55.58%) (37.50%) (18.80%) (71.10%) (32.15%) 0.05% 4.10%
ROA
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
ROIC
(54.18%) (92.46%) (1,563.81%) 145.85% (140.99%) (42.83%) (351.62%) 667.53% (0.88%) 19.64%
ROE
predictions in italic, sparklines do not include predictions

All 10 years →

Fiscal years to Dec 2025 · latest quarter Jun 2026

Seres Therapeutics, Inc. peers in Biotechnology

All 616 Biotechnology stocks →

Seres Therapeutics, Inc. (MCRB) key facts

  • Seres Therapeutics, Inc. (MCRB) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • As of September 25, 2026, MCRB traded at $3.52, a market capitalization of $36.0 million.
  • Return on equity was 19.6% and debt-to-equity 0.00.

Source: company filings (standardised) and stockrow calculations.

Seres Therapeutics, Inc. (MCRB) Latest News

News by impact score

Fine-tune

5 Aug

3

Seres Therapeutics reported second quarter 2026 financial results and business updates including steps to cut ongoing facilities costs. Quarterly results with facilities cost reductions may moderately shift financial outlook and market sentiment.

10 Jul

4

Seres Therapeutics’ SER-155 achieved an 80% response rate in a study reducing gastrointestinal toxicity from cancer immunotherapy. Positive SER-155 trial data signals major pipeline progress that can drive regulatory milestones and valuation gains.

8 Jul

4

Seres Therapeutics reports early clinical data for SER-155 showing potential to treat immune checkpoint inhibitor-related enterocolitis, a common side effect that often forces cancer patients to stop therapy. Positive early data on SER-155 for an expanded indication can materially boost pipeline value and investor sentiment for Seres.

13 Jun

3

Seres Therapeutics cash burn rate sparks investor concerns over financial runway and potential need for additional funding. Cash burn worries can pressure near-term funding needs and stock sentiment for the company.

5 Jun

4

Seres Therapeutics completed two transactions strengthening its balance sheet, cutting ongoing lease costs, and extending its operating cash runway into the first quarter of 2027. Transactions extend cash runway into 2027 while reducing costs, bolstering financial position for ongoing operations.

5 May

3

Seres Therapeutics reported first quarter 2026 financial results and provided business updates. Quarterly financial results and business updates moderately affect financial performance and investor sentiment.

20 Apr

3

Seres Therapeutics showcased SER-155 data and live biotherapeutic insights at ESCMID Global 2026. Presenting SER-155 data at a major conference boosts visibility for Seres' microbiome pipeline and could moderately impact investor sentiment.

3

Seres Therapeutics showcased SER-155 data and live biotherapeutic insights at ESCMID Global 2026. Showcasing pipeline data at a major conference boosts visibility and supports microbiome platform validation without transformative breakthroughs.

12 Mar

4

Seres Therapeutics (MCRB) released Q4 earnings snapshot detailing quarterly financial results. Q4 earnings snapshots directly impact financial performance, investor sentiment, and stock trajectory through key metrics like revenue and EPS.

4

Seres Therapeutics (MCRB) reported fourth quarter and full year 2025 financial results and provided business updates. Financial results and business updates directly influence investor sentiment, stock valuation, and future trajectory for biotech firms.

2 Mar

4

Seres Therapeutics appoints Richard N. Kender as Executive Chair and Interim CEO and provides business updates. Appointment of new Executive Chair and Interim CEO signals major leadership transition with potential to significantly alter strategic direction and investor sentiment.

12 Feb

4

Seres Therapeutics, Inc. is laying off staff and pausing its leading program as part of a strategic overhaul. The company aims to streamline operations and focus on its core assets amid ongoing challenges in the biotechnology sector. This decision reflects a significant shift in its business strategy as it seeks to improve financial stability and future prospects. The layoffs and program pause indicate a major strategic shift that could significantly impact the company's future and market performance.

4

Seres Therapeutics, Inc. has announced updates on its programs, emphasizing a strategic focus on emerging initiatives in inflammatory and immune diseases. The company is prioritizing these areas to enhance its research and development efforts, aiming to address unmet medical needs and improve patient outcomes. This shift reflects a commitment to advancing its pipeline and potentially expanding its market presence in these therapeutic domains. Prioritizing emerging programs in inflammatory and immune diseases indicates a significant strategic shift that could enhance the company's market positioning and investor sentiment.

6 Jan

4

Seres Therapeutics, Inc. announced the publication of research in Nature Medicine and the Journal of Infectious Diseases that elucidates the mechanism of action of Vowst™, its live biotherapeutic product. These publications support the broader strategy of utilizing live biotherapeutics in treating various diseases, potentially enhancing the company's position in the market. The publications highlight significant advancements in understanding Vowst™ and reinforce the company's strategic direction in live biotherapeutics, likely influencing investor sentiment and market performance.

29 Dec

3

Seres Therapeutics, Inc. (MCRB) is highlighted as one of three biotech stocks poised for a potential turnaround by 2026, following a period of significant decline. The company focuses on microbiome therapeutics, which are gaining attention for their innovative approach to treating various diseases. Analysts suggest that with upcoming clinical trials and a growing interest in microbiome research, Seres could see a resurgence in market performance. Investors are encouraged to consider the stock as part of a long-term strategy, despite its current challenges. Upcoming clinical trials and increased interest in microbiome therapeutics may moderately influence Seres Therapeutics' market performance.

5 Nov

3

Seres Therapeutics, Inc. (MCRB) reported its financial results for the third quarter of 2025, highlighting key business updates and financial metrics. The company continues to advance its pipeline of microbiome therapeutics, focusing on innovative treatments for various diseases. Management provided insights into ongoing clinical trials and strategic initiatives aimed at enhancing product development and market positioning. Overall, the report reflects the company's commitment to growth and innovation in the biopharmaceutical sector. The financial results and updates indicate moderate progress in product development and market strategy, which may influence future performance.

29 Oct

4

Seres Therapeutics, Inc. has been awarded up to $3.6 million from CARB-X to develop a liquid formulation of its investigational product SER-155, aimed at preventing infections in immunocompromised patients. This funding will support the advancement of SER-155, which is designed to restore gut microbiome diversity and improve patient outcomes. The award underscores CARB-X's commitment to combating antibiotic-resistant infections and highlights the potential of SER-155 in addressing significant healthcare challenges. The funding from CARB-X is a significant strategic move that could enhance product development and market positioning for Seres Therapeutics.

14 Oct

4

Seres Therapeutics, Inc. will present new post hoc data from the SER-155 Phase 1b trial at IDWeek 2025, focusing on its potential to enhance outcomes for adults undergoing allogeneic hematopoietic stem cell transplant. This presentation aims to showcase the therapeutic benefits of SER-155 in improving patient recovery and overall health post-transplant. The presentation of new data from a clinical trial could significantly influence investor sentiment and the company's future trajectory.

23 Sep

3

Seres Therapeutics, Inc. received constructive feedback from the FDA regarding the Phase 2 study protocol for SER-155, which is aimed at treating patients with hematologic malignancies. The company is also implementing cost reduction measures to extend its cash runway, indicating a strategic response to current financial conditions. FDA feedback on the study protocol and cost reduction actions may moderately influence Seres Therapeutics' operational and financial performance.

9 Sep

4

Seres Therapeutics, Inc. (MCRB) has received a rating upgrade to 'Buy' from analysts, reflecting increased confidence in the company's potential for growth and market performance. This upgrade is based on recent developments in their product pipeline and positive market sentiment surrounding their innovative therapies. Investors are encouraged to consider this upgrade as a signal of the company's strengthening position in the biotechnology sector. The rating upgrade indicates significant confidence in Seres Therapeutics' future performance and market position.

28 Aug

4

Seres Therapeutics, Inc. (MCRB) has experienced a positive technical outlook following the occurrence of a golden cross in its stock chart, indicating potential upward momentum. This technical indicator suggests that the stock's short-term moving average has crossed above its long-term moving average, often seen as a bullish signal by traders. Analysts are optimistic about the company's future performance, anticipating that this trend could attract more investors and enhance market sentiment towards Seres Therapeutics. The occurrence of a golden cross typically signals significant bullish momentum, which can substantially influence investor sentiment and market performance.

6 Aug

4

Seres Therapeutics, Inc. (MCRB) reported its financial results for the second quarter of 2025, highlighting key business updates and performance metrics. The company continues to advance its pipeline of microbiome therapeutics, focusing on innovative treatments for various diseases. Financial results indicate progress in revenue generation and investment in research and development, reflecting the company's commitment to its strategic goals. Management provided insights into upcoming milestones and ongoing clinical trials, emphasizing the potential for future growth. Significant advancements in product development and strategic updates are likely to influence the company's market position and investor sentiment.

3

Seres Therapeutics, Inc. reported its Q2 earnings, highlighting key financial metrics and developments in its product pipeline. The company continues to focus on advancing its microbiome therapeutics, with updates on clinical trials and regulatory progress. Financial results showed fluctuations in revenue and expenses, reflecting ongoing investments in research and development. The outlook for the remainder of the year includes expectations for further advancements in product development and potential market opportunities. The earnings report indicates moderate financial performance and ongoing product development that may influence the company's competitive positioning.

22 Jul

4

Seres Therapeutics, Inc. announced the appointment of Thomas DesRosier and Marella Thorell as co-CEOs, succeeding Eric Shaff, who will step down on July 31, 2025, after a decade with the company. DesRosier and Thorell will continue their roles as Chief Legal Officer and Chief Financial Officer, respectively. The company is engaging with multiple parties for potential business development and partnerships to secure additional capital for advancing SER-155 and other live biotherapeutic candidates. SER-155 has shown promise in reducing bloodstream infections in high-risk patients. The leadership transition aims to leverage their experience to enhance the company's strategy and clinical progression. The leadership transition and ongoing engagement for partnerships are significant strategic moves that could greatly influence the company's future performance and market position.

21 Jul

3

Seres Therapeutics, Inc. (NASDAQ:MCRB) has 51% of its shares held by individual investors, giving them significant influence over management and strategy. Institutions own 23% of the company, with Flagship Pioneering, Inc. being the largest shareholder at 13%. The top 21 shareholders collectively own 50%, indicating no single majority shareholder. Insider ownership is under 1%, suggesting limited alignment with shareholders. The general public's substantial stake allows them to impact decisions on executive compensation and business acquisitions. Private equity firms hold 13%, while public companies own 12%, indicating potential strategic interests. Investors should consider various ownership dynamics and associated risks. The significant ownership by individual investors and institutional presence suggests moderate influence on the company's future performance.

27 May

4

Seres Therapeutics, Inc. presented expanded exploratory biomarker data for SER-155 at the 2025 ASCO Annual Meeting, highlighting potential advancements in the treatment of patients with certain conditions. The data aims to provide insights into the efficacy and safety of SER-155, which could influence future clinical applications and research directions. The presentation of expanded biomarker data could significantly impact the company's future product development and market positioning.

23 May

4

Seres Therapeutics (MCRB) has been upgraded to a Zacks Rank #2 (Buy) due to an upward trend in earnings estimates, indicating a positive outlook for the company's earnings potential. The Zacks rating system, which is based on earnings estimate revisions, suggests that the stock may experience price increases as institutional investors respond to these changes. Analysts have raised their earnings estimates for Seres, projecting a loss of -$1.67 per share for the fiscal year ending December 2025, reflecting a significant year-over-year change. The upgrade places Seres in the top 20% of Zacks-covered stocks, suggesting strong potential for market-beating returns in the near term. The upgrade indicates significant improvements in earnings estimates, which could positively influence investor sentiment and stock performance.

16 May

4

Wall Street analysts project that Seres Therapeutics, Inc. (MCRB) could see a potential rally of 713.09%. The article outlines strategies for trading the stock, emphasizing the significant upside potential based on current market conditions and company performance metrics. The projected rally indicates a significant potential shift in investor sentiment and market dynamics for Seres Therapeutics.

7 May

3

Seres Therapeutics, Inc. reported its Q1 earnings, highlighting key financial metrics and developments in its product pipeline. The company continues to focus on advancing its microbiome therapeutics, with updates on clinical trials and regulatory progress. Investors are keenly observing these developments as they could influence future market performance. The earnings report indicates moderate progress in product development and financial performance, which may influence investor sentiment but is not expected to drastically change the company's trajectory.

3

Seres Therapeutics, Inc. (MCRB) reported its financial results for the first quarter of 2025, highlighting key business updates and developments. The company continues to advance its pipeline and strategic initiatives, focusing on innovative therapies in the microbiome space. Financial metrics indicate progress, with specific attention to revenue growth and research investments. Management provided insights into future plans and market positioning, emphasizing ongoing collaborations and potential product launches. The financial results and updates suggest moderate influence on Seres Therapeutics' performance and market sentiment.

stockrow.com/MCRB · Data as of Jun 30, 2026 · For information only; not investment advice. · © 2026 stockrow.com