Seres Therapeutics, Inc.

MCRB Healthcare Biotechnology

Seres Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $789,000.00, down 99.4% from fiscal 2023.

Revenue
+69.0%
EPS
−273.6%
Free cash flow
−576.7%

Quarter to September 2026, against a year earlier

1.97 0.12 −5.74%
Market cap
$20.8M
P/E
0.0×
Fwd P/E
−0.6×
Dividend yield
—
F-score
n/a
Altman Z
−10.99
Beneish M
n/a
Dividend safety
n/a

Insider Decisions last twelve months

Sold, $m 0.01
Trades a month
Jan 26 Apr 26 Jul 26 Oct 26
Buy — — — — — — — — — — — —
Sell — — 4 — — 4 — — 4 — — —
Insider Ownership 23.86%

Capital & Financial Ratios $m

Size
Market Cap 20.78
Revenue ttm 2.13
Net income ttm (46.95)
Free cash flow ttm (63.70)
Net debt Q (17.53)
Valuation
P/E 0.00
Forward P/E (0.56) (negative: loss-making)
Price / sales 9.25
Forward P/S Powerpack
Price / FCF 0.00
Price / book 0.92
Financial health
Current ratio Q 1.65 (at or above 1.5: strong)
Debt / equity Q 0.00 (at or below 0.5: strong)
Interest coverage Q (8.38)
Growth
Revenue growth Q +68.95% (above 0%: growing)
Operating income growth Q +28.14% (above 0%: growing)
EPS, this year −699.79% (below 0%: weak)
EPS, next year A +34.99% (at or above 15%: strong)
Revenue, next year A +1,649.05% (at or above 10%: strong)
EPS, past 5 yrs —
EPS, next 5 yrs A +25.41% (at or above 15%: strong)

Green and red mark values outside typical ranges; (Q) is the latest quarter, (A) analysts’ estimates. How we judge →

Valuation vs history

P/S against its own 10 years 50.61%
10-year low 10-year high
P/B against its own 10 years 0.38%
10-year low 10-year high
EV/Sales against its own 10 years 77.18%
10-year low 10-year high

Dividends

Yield
—
Annual rate
—
Payout ratio
—

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 128 31 46 18
Receivables 9 2 1 13
Inventory — — — —
Other — — — —
175 39 49 34
2023 2024 2025 Q'26
Payables 4 4 2 1
ST’ Debt — — — —
Other — — — —
99 41 19 21

Compound Annual Growth %

10y 5y 3y
Sales — (53.03%) (82.41%)
Cash Flow 0.00% 0.00% 0.00%
Earnings 0.00% 0.00% 0.00%
Book Value (14.24%) (24.03%) 60.06%

Earnings Trends EPS, adjusted, against the consensus

EPS $

Mar Jun Sep Dec Year
’26 (2.08) 0.47 (1.63) — —
’25 3.75 (2.27) 0.94 (1.76) 0.64
’24 (5.40) (4.40) 11.60 (1.78) 0.00
’23 (11.40) 7.20 (7.40) (6.40) (17.80)
’22 (12.20) (14.00) (9.80) (10.80) (46.20)
’21 (7.80) (10.60) 14.40 (11.00) (14.40)
’20 (5.60) (5.60) (7.20) (3.60) (22.40)
Fiscal quarters ending in the months shown.

Revenue $m

Mar Jun Sep Dec Year
’26 0 1 1 — —
’25 — — 0 0 1
’23 (1) 126 0 0 126
’22 1 1 3 1 7
’21 6 5 127 7 145
’20 8 6 1 18 33
’19 7 13 7 8 35
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (16) (22) (10) — —
’25 27 (13) 2 (15) 1
’24 (35) (40) (35) (39) (149)
’23 (77) 66 (59) (47) (117)
’22 (66) (50) (60) (53) (229)
’21 (29) (40) 128 (52) 7
’20 (24) (26) (26) (18) (94)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (16) (22) (10) — —
’25 27 (13) 2 (15) 1
’24 (35) (40) (35) (39) (149)
’23 (81) 65 (61) (48) (125)
’22 (69) (52) (61) (56) (239)
’21 (31) (42) 124 (53) (3)
’20 (24) (26) (26) (18) (94)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Ten-year view Analyst estimates Powerpack
Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 TTM Sep ’26 Trend 10 yrs 2026e 2027e 2028e Next 3/yr
Income, $m
Income, $m Revenue 22 32 28 35 33 145 7 126 — 1 2 (30.8%) 14 0 0 (29.8%)
Gross margin, % 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 — 100.00 100.00 0.0 pt
EBT (92) (89) (99) (70) (89) (66) (184) (190) (126) 6 (47) n/m
EBT margin, % (420.74) (278.44) (350.03) (203.68) (268.33) (45.25) (2,575.49) (150.51) 0.00 721.93 (2,209.55) +1,142.7 pt
Net income (92) (89) (99) (70) (89) (66) (250) (114) 0 6 (47) n/m
Per share, $
Per share, $ Revenue 10.92 15.87 13.88 12.18 8.33 31.61 1.32 19.74 0.00 0.09 0.21 (41.4%)
Earnings (46.00) (44.20) (48.60) (24.80) (22.40) (14.40) (46.20) (17.80) 0.00 0.64 (5.00) n/m
Cash flow 22.04 (37.34) (30.85) (27.01) (23.46) 1.46 (42.34) (18.34) (19.13) 0.13 (6.41) (43.7%)
Capex (10.79) (2.31) (0.95) (0.35) (0.15) (2.09) (1.82) (1.25) (0.05) 0.00 0.02 (57.7%)
Free cash flow 11.26 (39.65) (31.80) (27.37) (23.61) (0.63) (44.16) (19.58) (19.17) 0.12 (6.38) (39.6%)
Book value 66.57 30.01 (23.58) (17.06) 43.80 28.68 2.00 (7.01) 1.77 4.99 2.14 (25.0%)
Shares, m 2 2 2 3 4 5 5 6 8 9 10 +18.0%
Valuation, ×
Valuation, × P/E 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 — 22.21 0.00 2.5
P/S 18.33 13.29 6.52 5.66 58.85 5.27 81.88 1.42 — 89.49 9.25 31.2
P/B 3.01 7.03 0.00 0.00 11.19 5.81 54.12 0.00 — 2.98 0.92 9.3
EV/Sales 9.94 8.90 3.72 3.63 51.96 3.44 63.53 1.21 — 128.00 49.24 30.5
EV/FCF 9.65 (3.56) (1.62) (1.62) (18.32) (172.98) (1.90) (1.22) — 175.40 (1.64) (1.8)
Cash, $m
Cash, $m Operating cash flow 44 (76) (63) (77) (94) 7 (229) (117) (149) 1 (64) (33.5%)
Capex (21) (5) (2) (1) (1) (10) (10) (8) 0 0 0 (50.0%)
Free cash flow 22 (80) (65) (78) (94) (3) (239) (125) (149) 1 (64) (28.6%)
Balance, $m
Balance, $m Working capital 168 123 51 54 222 221 109 77 (3) 30 14 (17.4%)
Net debt (183) (141) (79) (70) (229) (266) (131) (26) (31) (46) (18) (14.2%)
Shareholders’ equity 133 61 (48) (48) 175 132 11 (45) 14 44 21 (11.5%)
Returns, %
Returns, % ROA (37.41) (38.68) (63.83) (55.58) (37.50) (18.80) (71.10) (32.15) 0.05 4.10 (44.85) +41.5 pt
ROIC 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 (1,267.77) 0.0 pt
ROE (54.18) (92.46) (1,563.81) 145.85 (140.99) (42.83) (351.62) 667.53 (0.88) 19.64 (144.35) +73.8 pt
People
People Employees 127 138 145 108 155 333 431 160 103 66 — (7.0%)
Revenue/emp, $m 0.17 0.23 0.19 0.32 0.21 0.44 0.02 0.79 0.00 0.01 — (25.6%)
Negative figures in brackets.
estimates

All 10 years →

Fiscal years to Dec 2025 · latest quarter Sep 2026 · fundamentals updated 6 Nov 2026

Seres Therapeutics, Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
EVAX Evaxion A/S - Sponsored ADR $23.0M — (loss-making) — (loss-making) +14,590.20% (above 0%: growing) n/m −56.70% (below 0%: shrinking) 100.00% 0.00% Compare
IGC IGC Pharma, Inc. $22.0M — (loss-making) — (loss-making) 0.00% n/m −45.33% (below 0%: shrinking) 18.60% (588.72%) Compare
CRVO CervoMed Inc. $21.9M — (loss-making) — (loss-making) −99.60% (below 0%: shrinking) n/m −6.20% (below 0%: shrinking) 100.00% 0.00% Compare
FLNA Cassava Sciences, Inc. $21.8M — (loss-making) — +1,328.04% (above 0%: growing) n/m +21.65% (above 0%: growing) 0.00% 0.00% Compare
MCRB Seres Therapeutics, Inc. $20.8M — (loss-making) — (loss-making) +68.95% (above 0%: growing) n/m −576.66% (below 0%: shrinking) 100.00% (2,723.78%)
ATOS Atossa Therapeutics, Inc. $20.2M — (loss-making) — −94.28% (below 0%: shrinking) n/m −32.86% (below 0%: shrinking) 0.00% 0.00% Compare
IMMP Prima BioMed Ltd $19.8M — — — n/m −589,653.13% (below 0%: shrinking) 100.00% (101.89%) Compare
BSEM BioStem Technologies, Inc. $19.4M — (loss-making) — (loss-making) −27.95% (below 0%: shrinking) n/m — 61.28% (106.35%) Compare
COCP Cocrystal Pharma, Inc. $19.3M — (loss-making) — (loss-making) −81.05% (below 0%: shrinking) n/m −16.75% (below 0%: shrinking) 100.00% (3,032.38%) Compare
Median of peers $21.0M — — −27.95% — −32.86% 80.64% (50.94%)

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Pay and ownership Proxy statement filed 27 April 2026

Ownership

Directors and executive officers, together 5.20%
Entities affiliated with Flagship Pioneering 12.00%
Nestlé S.A. 11.30%
Ownership is the proxy’s own table: the directors and officers as a group, and every holder of 5% or more. Read the proxy statement

Seres Therapeutics, Inc. (MCRB) Latest News

29 Dec

14 Oct

6 Aug

22 Jul

Impact 4 · · GlobeNewswire
stockrow.com/MCRB · Data as of Nov 6, 2026 · For information only; not investment advice. · © 2026 stockrow.com