Ligand Pharmaceuticals Incorporated

LGND Healthcare Biotechnology

Ligand Pharmaceuticals Incorporated’s revenue for fiscal 2025 (year ended December 2025) was $268.1 million, up 60.4% from fiscal 2024.

Revenue
−31.8%
EPS
−123.9%
Free cash flow
−268.5%
Total debt
+52.6%

Quarter to September 2026, against a year earlier

306.43 7.43 +2.48%
Market cap
$6.0B
P/E
116×
Fwd P/E
88.3×
Dividend yield
—
F-score
6/9
Altman Z
5.45
Beneish M
−4.02
Dividend safety
n/a

Ligand Pharmaceuticals Incorporated (LGND) Operating margin

Alert me on Operating margin

Ligand Pharmaceuticals Incorporated's operating margin over the twelve months to 30 September 2026 was 9.29%, down 6.0 percentage points from fiscal 2025 (15.3%). Over the past ten years it has ranged from −13.5% (fiscal 2024) to 671.0% (fiscal 2019); the current reading is higher than 36% of that period. That is above the Biotechnology industry median of 0.00% and above the Healthcare sector median of 0.00%.

Operating margin, annual

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Annual newest first

Period Operating margin Change (points)
FY2025 15.3% 28.82
FY2024 −13.5% (22.62)
FY2023 9.09% 7.54
FY2022 1.55% (41.44)
FY2021 43.0% 20.06
FY2020 22.9% (648.06)
FY2019 671.0% 605.88
FY2018 65.1% 16.86
FY2017 48.3% 7.98
FY2016 40.3% 2.27

Quarterly newest first

Period Operating margin Change (points)
Sep 2026 −20.0% (33.50)
Jun 2026 13.5% (20.09)
Mar 2026 33.6% 11.14
Dec 2025 22.4% (25.53)
43 more quarters

Against its own ten years

Low −13.5% High 671.0%
Ten-year median 38.0%
Current reading's percentile 37

Operating margin against peers

Company Operating margin
PTCT PTC Therapeutics, Inc. compare 12.8%
LGND Ligand Pharmaceuticals Incorporated 9.29%
KOD Kodiak Sciences Inc. compare 0.00%
ORKA Oruka Therapeutics, Inc. compare 0.00%
IMVT Immunovant, Inc. compare 0.00%
BLTE Belite Bio, Inc. Sponsored ADR compare 0.00%
IONS Ionis Pharmaceuticals, Inc. compare −68.0%
MIRM Mirum Pharmaceuticals, Inc. compare −133.6%
CGON CG Oncology, Inc. compare −4,056.2%
Biotechnology industry median 0.00%
Healthcare sector median 0.00%
Market median 0.00%

What Operating margin is

EBIT Margin tells an investor how much operating profit, before interest and taxes, a company keeps from each unit of revenue.

EBIT ÷ Revenue

The full definition of Operating margin →

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