Iterum Therapeutics PLC

ITRMF Healthcare Biotechnology

In the quarter to September 2025, revenue grew 110.8%, EPS grew 33.3% and free cash flow fell 179.2%, each against the same quarter a year earlier. Insiders bought in the last twelve months.

0.00 0.00 NaN
Market cap
$1.6M
P/E
0.0×
Fwd P/E
−1.0×
Dividend yield
—
F-score
2/9
Altman Z
−26.27
Beneish M
22.81
Dividend safety
n/a

Insider Decisions trades per month

Total buys 0.00
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy 1 — — — — — — — — — — —
Sell — — — — — — — — — — — —
Insider Ownership 0.00%

Capital & Financial Ratios $m

Market Cap 1.59
Revenue 0.92
Net Income (26.96)
Free Cash Flow (19.53)
Net Debt 10.21
Current Ratio 2.13 (at or above 1.5: strong)
Debt/Equity (2.87) (negative: negative equity)
P/E ratio 0.00
Fwd P/E (1.00) (negative: loss-making)
P/S ratio 0.00
P/B ratio 0.00
Past 5Y EPS Growth —
This Y EPS Growth 67.12% (at or above 15%: strong)
Next Y EPS Growth 316.67% (at or above 15%: strong)
Next Y revenue growth (100.00%) (below 0%: weak)
Next 5Y EPS Growth 22.77% (at or above 15%: strong)

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

EV/Sales against its own 10 years 12.89%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
2018 Powerpack
special payouts not included in total or ratios

Assets vs Liabilities $m

2022 2023 2024 Q'25
Cash 61 24 24 11
Receivables 0 0 0 0
Inventory — — — 1
Other — — — —
62 26 25 14
2022 2023 2024 Q'25
Payables 3 5 0 1
ST’ Debt — — — —
Other 2 1 15 0
9 14 18 6

Compound Annual Growth %

10y 5y 3y
Sales — — —
Cash Flow — 0.00% 0.00%
Earnings — 0.00% 0.00%
Book Value — 0.00% 0.00%

Revenue $m

Mar Jun Sep Dec Year
’26 — — 0 — —
’19 0 — — — 0
’18 0 0 0 0 1
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (3) (5) (7) — —
’24 (13) (7) (3) (4) (27)
’23 (10) (8) (9) (13) (39)
’22 (3) (6) (5) (4) (18)
’21 (1) (8) (4) (2) (16)
’20 (27) (14) (4) (9) (55)
’19 (15) (18) (25) (23) (82)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (3) (5) (7) — —
’24 (13) (7) (3) (4) (27)
’23 (10) (8) (9) (13) (39)
’22 (3) (6) (5) (4) (19)
’21 (1) (8) (4) (2) (16)
’20 (27) (14) (4) (9) (55)
’19 (15) (18) (25) (23) (82)
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 (0.14) (0.16) (0.20) — —
’24 (0.46) (0.30) (0.30) (0.25) (1.26)
’23 (0.78) (0.95) (0.30) (0.94) (2.96)
’22 (0.30) (0.60) (2.38) (0.41) (3.63)
’21 (12.14) 0.60 0.30 (0.30) (8.40)
’20 (16.19) (11.99) (9.00) (4.20) (32.53)
’19 (21.59) (28.94) (32.23) (23.84) (106.45)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

2
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Group Line 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 Trend 2025e 2026e 2027e
Price, $
Price, $ Low — — — 75.15 25.20 6.77 5.86 0.60 0.62 0.81

Analyst estimates 2025–2027

Powerpack
High — — — 195.00 139.51 90.30 44.93 7.05 2.50 3.02
People
People Employees — — 38 48 44 7 13 14 14 9
Revenue/emp, $m — — 0.01 0.02 0.00 0.00 0.00 0.00 0.00 0.00
Income, $m
Income, $m Revenue — — 1 1 0 — — — — —
Gross margin, % — — 100.00 100.00 100.00 0.00 0.00 0.00 — 0.00
EBT — (13) (29) (77) (103) (51) (91) (44) (38) (25)
EBT margin, % — 0.00 (5,701.18) (8,812.89) (277,529.73) 0.00 0.00 0.00 0.00 0.00
Net income — (13) (29) (77) (103) (52) (92) (44) (38) (25)
Depreciation — — 0 0 1 11 6 4 4 3
Per share, $
Per share, $ Revenue — 0.00 44.17 1.49 0.04 0.00 0.00 0.00 0.00 0.00
Earnings — (8,528.78) (2,561.26) (132.23) (106.45) (32.53) (8.40) (3.63) (2.96) (1.26)
Cash flow — (7,061.25) (2,661.22) (130.26) (84.60) (34.05) (1.45) (1.51) (3.03) (1.36)
Capex — 0.00 (70.61) (0.15) (0.02) (0.01) (0.01) (0.01) 0.00 0.00
Free cash flow — (7,061.25) (2,731.83) (130.42) (84.62) (34.05) (1.46) (1.51) (3.04) (1.36)
Book value — 14,186.25 3,434.26 122.94 (27.09) (31.57) 4.61 2.29 (0.49) (0.21)
Shares, m — 0 0 1 1 2 11 12 13 20
Valuation, ×
Valuation, × P/E — — 0.00 0.00 0.00 — — — — —
P/S — — 0.00 50.38 91.42 — — — — —
P/B — — 0.11 0.61 0.00 — — — — —
EV/Sales — — 0.00 (30.73) 103.44 — — — — —
EV/FCF — — 0.52 0.35 (0.90) — — — — —
Cash, $m
Cash, $m Operating cash flow — (11) (31) (76) (82) (55) (16) (18) (39) (27)
Capex — — (1) 0 0 0 0 0 0 0
Free cash flow — (11) (31) (76) (82) (55) (16) (19) (39) (27)
Balance, $m
Balance, $m Working capital — 22 37 81 (25) (20) 70 53 12 7
Total debt — — — 14 13 29 9 10 11 20
Net debt — (25) (39) (70) 9 14 (73) (51) (12) (4)
Shareholders’ equity — 23 39 72 (26) (51) 50 28 (6) (4)
Returns, %
Returns, % ROA — (36.55) (79.83) (106.56) (166.85) (177.67) (147.33) (56.12) (82.44) (69.93)
ROIC — 0.00 (6,622.08) (4,201.00) 0.00 0.00 0.00 0.00 0.00 0.00
ROE — (43.29) (94.61) (138.69) (454.48) 135.44 56,347.08 (113.59) (355.35) 472.61
Negative figures in brackets.

All 10 years →

Fiscal years to Dec 2019 · latest quarter Sep 2025

Charts ten years each

Iterum Therapeutics PLC vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
SILO Silo Pharma, Inc. $1.9M — (loss-making) 18.4× 0.00% n/m +39.17% (above 0%: growing) (15.00%) 0.00% Compare
GNPX GENPREX $1.9M 0.0× — — n/m −32.98% (below 0%: shrinking) 0.00% 0.00% Compare
TRVN Trevena, Inc. $1.8M — (loss-making) — (loss-making) +57.22% (above 0%: growing) n/m +49.55% (above 0%: growing) 59.72% (1,970.67%) Compare
NEXI NexImmune, Inc. $1.6M — (loss-making) — — n/m +66.38% (above 0%: growing) 0.00% 0.00% Compare
ITRMF Iterum Therapeutics PLC $1.6M — (loss-making) — (loss-making) +110.81% (above 0%: growing) n/m −179.15% (below 0%: shrinking) 94.87% (1,982.31%)
CARM Carisma Therapeutics Inc. $1.5M — (loss-making) — (loss-making) +392.01% (above 0%: growing) n/m +114.65% (above 0%: growing) 100.00% 96.83% Compare
ARTL Artelo Biosciences, Inc. $1.5M — (loss-making) — — n/m −879.18% (below 0%: shrinking) 0.00% 0.00% Compare
ABPO Abpro Holdings Inc. $1.4M 0.2× — — n/m −0.48% (below 0%: shrinking) 100.00% 0.00% Compare
MLEC Moolec Science SA $1.4M — (loss-making) — (loss-making) +948.39% (above 0%: growing) n/m +4.48% (above 0%: growing) (25.52%) (77.92%) Compare
Median of peers $1.6M — — +224.62% — +21.83% 0.00% 0.00%

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Iterum Therapeutics PLC (ITRMF) Latest News

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