Dyadic International Inc.

DYAI Healthcare Biotechnology

Dyadic International Inc.’s revenue for fiscal 2025 (year ended December 2025) was $3.1 million, down 11.6% from fiscal 2024. In the quarter to June 2026, revenue was flat, EPS was flat, free cash flow fell 1,298.5% and total debt was flat, each against the same quarter a year earlier.

0.41 0.01 −2.38%
Market cap
$16.8M
P/E
0.0×
Fwd P/E
−7.4×
Dividend yield
—
F-score
2/9
Altman Z
−12.37
Beneish M
1.00
Dividend safety
n/a

Insider Decisions trades per month

Total sells 0.12
Totals in millions of $.
Dec 25 Mar 26 Jun 26 Sep 26
Buy — — — — — — — — — — — —
Sell — — — — — — — — 1 — — —
Insider Ownership 15.37%

Capital & Financial Ratios $m

Market Cap 16.80
Revenue 3.80
Net Income (7.62)
Free Cash Flow (7.40)
Net Debt 0.37
Current Ratio 1.65 (at or above 1.5: strong)
Debt/Equity (2.11) (negative: negative equity)
P/E ratio 0.00
Fwd P/E (7.35) (negative: loss-making)
P/S ratio 3.93
P/B ratio 0.00
Past 5Y EPS Growth —
This Y EPS Growth 39.13% (at or above 15%: strong)
Next Y EPS Growth 121.43% (at or above 15%: strong)
Next Y revenue growth 113.18% (at or above 10%: strong)
Next 5Y EPS Growth 64.84% (at or above 15%: strong)

Green and red mark values outside typical ranges. How we judge →

Valuation vs history

P/S against its own 10 years 0.24%
10-year low 10-year high
EV/Sales against its own 10 years 2.88%
10-year low 10-year high

Dividends

Payout Ratio —
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
2017 Powerpack
special payouts not included in total or ratios

Assets vs Liabilities $m

2023 2024 2025 Q'26
Cash 7 9 9 5
Receivables 0 0 1 1
Inventory — — — —
Other — — — —
8 10 10 6
2023 2024 2025 Q'26
Payables 1 0 1 1
ST’ Debt — — — —
Other — — — —
2 2 4 4

Compound Annual Growth %

10y 5y 3y
Sales 25.61% 14.04% 1.79%
Cash Flow — 0.00% 0.00%
Earnings 0.00% 0.00% 0.00%
Book Value — (46.62%) (51.92%)

Revenue $m

Mar Jun Sep Dec Year
’26 1 1 — — —
’25 0 1 1 1 3
’24 0 0 2 1 3
’23 1 1 0 1 3
’22 1 1 1 1 3
’21 0 1 1 0 2
’20 0 1 0 0 2
Fiscal quarters ending in the months shown.

Operating Cash Flow $m

Mar Jun Sep Dec Year
’26 (2) (2) — — —
’25 (2) 0 (2) (2) (6)
’24 (1) (2) 0 (1) (4)
’23 (2) (2) (2) (1) (7)
’22 (3) (2) (2) (2) (8)
’21 (2) (2) (4) (3) (11)
’20 (2) (2) (1) (1) (7)
Fiscal quarters ending in the months shown.

Free Cash Flow $m

Mar Jun Sep Dec Year
’26 (2) (2) — — —
’25 (2) 0 (2) (2) (6)
’24 (1) (2) 0 (1) (4)
’23 (2) (2) (2) (1) (7)
’22 (3) (2) (2) (2) (8)
’21 (2) (2) (4) (3) (11)
’20 (2) (2) (1) (1) (7)
Fiscal quarters ending in the months shown.

EPS $

Mar Jun Sep Dec Year
’26 (0.05) (0.06) — — —
’25 (0.07) (0.06) (0.06) (0.06) (0.23)
’24 (0.07) (0.07) (0.01) (0.05) (0.20)
’23 (0.03) (0.07) (0.06) (0.08) (0.24)
’22 (0.09) (0.12) (0.06) (0.07) (0.34)
’21 (0.12) (0.14) (0.06) (0.15) (0.47)
’20 (0.08) (0.10) (0.09) (0.07) (0.34)
Fiscal quarters ending in the months shown.

Target Price Range

Analyst price targets

Recommendation Rating

1
1Buy 2 3Hold 4 5Sell

Ten years at a glance Fiscal years to December

Group Line 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 Trend 2026e 2027e 2028e
Price, $
Price, $ Low 1.32 1.23 1.38 1.77 2.51 3.15 1.12 1.20 0.93 0.71

Analyst estimates 2026–2028

Powerpack
High 1.85 1.81 2.29 7.30 10.98 8.78 4.98 2.40 2.67 2.14
People
People Employees — — 6 6 6 7 7 7 6 5
Revenue/emp, $m 0.00 0.00 0.22 0.28 0.27 0.34 0.42 0.41 0.58 0.62
Income, $m
Income, $m Revenue 1 1 1 2 2 2 3 3 3 3
Gross margin, % 100.00 10.31 20.70 13.17 11.05 19.11 27.54 31.84 65.82 24.93
EBT 1 (2) (7) (8) (9) (13) (10) (7) (6) (7)
EBT margin, % 100.00 (290.41) (517.01) (493.59) (580.19) (543.73) (332.23) (234.42) (166.20) (238.31)
Net income 0 (2) (6) (8) (9) (13) (10) (7) (6) (7)
Depreciation — 1 1 0 0 0 0 0 0 0
Per share, $
Per share, $ Revenue 0.02 0.03 0.05 0.06 0.06 0.09 0.10 0.10 0.12 0.09
Earnings (0.10) (0.07) (0.21) (0.31) (0.34) (0.47) (0.34) (0.24) (0.20) (0.23)
Cash flow (0.17) (0.06) (0.16) (0.21) (0.24) (0.41) (0.28) (0.23) (0.14) (0.17)
Capex 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Free cash flow (0.17) (0.06) (0.16) (0.21) (0.24) (0.41) (0.28) (0.23) (0.14) (0.17)
Book value 1.58 1.73 1.53 1.33 1.04 0.66 0.39 0.20 0.08 0.04
Shares, m 37 29 28 27 27 28 28 29 29 33
Valuation, ×
Valuation, × P/E 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
P/S 0.00 63.08 40.39 83.21 92.26 52.35 13.36 15.80 14.68 9.92
P/B 0.00 0.96 1.23 3.90 5.20 6.84 3.53 7.79 20.77 24.88
EV/Sales (8.35) 0.25 8.57 62.85 74.10 43.92 9.04 13.33 13.45 8.78
EV/FCF 0.00 (0.15) (2.46) (17.93) (17.76) (9.27) (3.23) (5.65) (11.51) (4.67)
Cash, $m
Cash, $m Operating cash flow (6) (2) (4) (6) (7) (11) (8) (7) (4) (6)
Capex — — — — — — — — — —
Free cash flow (6) (2) (4) (6) (7) (11) (8) (7) (4) (6)
Balance, $m
Balance, $m Working capital 57 49 42 34 28 18 11 6 7 6
Total debt — — — — — — — — 5 5
Net debt (56) (48) (41) (34) (29) (20) (13) (7) (4) (4)
Shareholders’ equity 58 50 42 36 28 18 11 6 2 1
Returns, %
Returns, % ROA 0.00 (8.42) (12.10) (20.58) (27.62) (50.89) (55.61) (61.97) (64.01) (74.11)
ROIC 26.74 20.70 (380.11) (353.37) 0.00 0.00 0.00 0.00 0.00 0.00
ROE (12.14) (3.97) (12.32) (21.22) (29.00) (55.81) (66.05) (80.11) (139.16) (397.80)
Negative figures in brackets.

All 10 years →

Fiscal years to Dec 2025 · latest quarter Jun 2026

Charts ten years each

Dyadic International Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier

Company Market cap P/E Fwd P/E Revenue growth (Q) EPS growth (Q) FCF growth (Q) Gross margin (Q) EBIT margin (Q) Compare
ATYR aTyr Pharma, Inc. $18.0M — (loss-making) — (loss-making) −90.75% (below 0%: shrinking) n/m +32.22% (above 0%: growing) 100.00% 0.00% Compare
NEUP Neuphoria Therapeutics Inc. $17.9M — (loss-making) — (loss-making) −107.32% (below 0%: shrinking) n/m +133.86% (above 0%: growing) 100.00% 0.00% Compare
JSPR Jasper Therapeutics, Inc. $17.7M — (loss-making) — — n/m +55.74% (above 0%: growing) 0.00% 0.00% Compare
ANEB Anebulo Pharmaceuticals, Inc. $17.6M — (loss-making) — — n/m +6.58% (above 0%: growing) — 0.00% Compare
ACGN Aceragen, Inc. $17.1M — (loss-making) — (loss-making) +2,394.95% (above 0%: growing) n/m −115.67% (below 0%: shrinking) 100.00% (834.33%) Compare
RADX Radiopharm Theranostics Limited - Sponsored ADR $17.0M — — — — −137.75% (below 0%: shrinking) — — Compare
DYAI Dyadic International Inc. $16.8M — (loss-making) — (loss-making) −0.57% (below 0%: shrinking) n/m −1,298.54% (below 0%: shrinking) (2.39%) (213.73%)
PBM Psyence Biomedical Ltd. $16.5M 0.2× — — n/m −707.20% (below 0%: shrinking) — 0.00% Compare
TCRX TScan Therapeutics, Inc. $16.2M — (loss-making) — (loss-making) −65.83% (below 0%: shrinking) n/m +18.95% (above 0%: growing) 100.00% (2,901.33%) Compare
Median of peers $17.4M — — −78.29% — +12.76% 100.00% 0.00%

All 614 Biotechnology stocks →

Dyadic International Inc. (DYAI) key facts

  • Concern: Dyadic International Inc.’s revenue for fiscal 2025 (year ended December 2025) was $3.1 million, down 11.6% from fiscal 2024.
  • Dyadic International Inc. (DYAI) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
  • As of October 16, 2026, DYAI traded at $0.41, a market capitalization of $16.8 million.
  • Return on equity was −397.8% and debt-to-equity -2.11.
  • Its Piotroski F-score is 2 out of 9 and its Altman Z-score is −12.37 (distress zone) for fiscal 2025.

Source: company filings (standardised) and stockrow calculations.

Dyadic International Inc. (DYAI) Latest News

19 Aug

14 Aug

Impact 3 ·

2 Jun

Impact 3 · transcript

20 May

Impact 3 ·

30 Mar

Impact 4 ·

22 Dec

stockrow.com/DYAI · Data as of Jun 30, 2026 · For information only; not investment advice. · © 2026 stockrow.com