Saturday 17 October 2026
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Dyadic International Inc.
DYAI Healthcare Biotechnology
Dyadic International Inc.’s revenue for fiscal 2025 (year ended December 2025) was $3.1 million, down 11.6% from fiscal 2024. In the quarter to June 2026, revenue was flat, EPS was flat, free cash flow fell 1,298.5% and total debt was flat, each against the same quarter a year earlier.
0.41
0.01
−2.38%
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Target Price Range
Analyst price targets
Free accountTen years at a glance Fiscal years to December
| Group | Line | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Trend | 2026e | 2027e | 2028e |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Price, $ | |||||||||||||||
| Price, $ | Low | 1.32 | 1.23 | 1.38 | 1.77 | 2.51 | 3.15 | 1.12 | 1.20 | 0.93 | 0.71 |
Analyst estimates 2026–2028 Powerpack |
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| High | 1.85 | 1.81 | 2.29 | 7.30 | 10.98 | 8.78 | 4.98 | 2.40 | 2.67 | 2.14 | |||||
| People | |||||||||||||||
| People | Employees | — | — | 6 | 6 | 6 | 7 | 7 | 7 | 6 | 5 | ||||
| Revenue/emp, $m | 0.00 | 0.00 | 0.22 | 0.28 | 0.27 | 0.34 | 0.42 | 0.41 | 0.58 | 0.62 | |||||
| Income, $m | |||||||||||||||
| Income, $m | Revenue | 1 | 1 | 1 | 2 | 2 | 2 | 3 | 3 | 3 | 3 | ||||
| Gross margin, % | 100.00 | 10.31 | 20.70 | 13.17 | 11.05 | 19.11 | 27.54 | 31.84 | 65.82 | 24.93 | |||||
| EBT | 1 | (2) | (7) | (8) | (9) | (13) | (10) | (7) | (6) | (7) | |||||
| EBT margin, % | 100.00 | (290.41) | (517.01) | (493.59) | (580.19) | (543.73) | (332.23) | (234.42) | (166.20) | (238.31) | |||||
| Net income | 0 | (2) | (6) | (8) | (9) | (13) | (10) | (7) | (6) | (7) | |||||
| Depreciation | — | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||||
| Per share, $ | |||||||||||||||
| Per share, $ | Revenue | 0.02 | 0.03 | 0.05 | 0.06 | 0.06 | 0.09 | 0.10 | 0.10 | 0.12 | 0.09 | ||||
| Earnings | (0.10) | (0.07) | (0.21) | (0.31) | (0.34) | (0.47) | (0.34) | (0.24) | (0.20) | (0.23) | |||||
| Cash flow | (0.17) | (0.06) | (0.16) | (0.21) | (0.24) | (0.41) | (0.28) | (0.23) | (0.14) | (0.17) | |||||
| Capex | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |||||
| Free cash flow | (0.17) | (0.06) | (0.16) | (0.21) | (0.24) | (0.41) | (0.28) | (0.23) | (0.14) | (0.17) | |||||
| Book value | 1.58 | 1.73 | 1.53 | 1.33 | 1.04 | 0.66 | 0.39 | 0.20 | 0.08 | 0.04 | |||||
| Shares, m | 37 | 29 | 28 | 27 | 27 | 28 | 28 | 29 | 29 | 33 | |||||
| Valuation, × | |||||||||||||||
| Valuation, × | P/E | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | ||||
| P/S | 0.00 | 63.08 | 40.39 | 83.21 | 92.26 | 52.35 | 13.36 | 15.80 | 14.68 | 9.92 | |||||
| P/B | 0.00 | 0.96 | 1.23 | 3.90 | 5.20 | 6.84 | 3.53 | 7.79 | 20.77 | 24.88 | |||||
| EV/Sales | (8.35) | 0.25 | 8.57 | 62.85 | 74.10 | 43.92 | 9.04 | 13.33 | 13.45 | 8.78 | |||||
| EV/FCF | 0.00 | (0.15) | (2.46) | (17.93) | (17.76) | (9.27) | (3.23) | (5.65) | (11.51) | (4.67) | |||||
| Cash, $m | |||||||||||||||
| Cash, $m | Operating cash flow | (6) | (2) | (4) | (6) | (7) | (11) | (8) | (7) | (4) | (6) | ||||
| Capex | — | — | — | — | — | — | — | — | — | — | |||||
| Free cash flow | (6) | (2) | (4) | (6) | (7) | (11) | (8) | (7) | (4) | (6) | |||||
| Balance, $m | |||||||||||||||
| Balance, $m | Working capital | 57 | 49 | 42 | 34 | 28 | 18 | 11 | 6 | 7 | 6 | ||||
| Total debt | — | — | — | — | — | — | — | — | 5 | 5 | |||||
| Net debt | (56) | (48) | (41) | (34) | (29) | (20) | (13) | (7) | (4) | (4) | |||||
| Shareholders’ equity | 58 | 50 | 42 | 36 | 28 | 18 | 11 | 6 | 2 | 1 | |||||
| Returns, % | |||||||||||||||
| Returns, % | ROA | 0.00 | (8.42) | (12.10) | (20.58) | (27.62) | (50.89) | (55.61) | (61.97) | (64.01) | (74.11) | ||||
| ROIC | 26.74 | 20.70 | (380.11) | (353.37) | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |||||
| ROE | (12.14) | (3.97) | (12.32) | (21.22) | (29.00) | (55.81) | (66.05) | (80.11) | (139.16) | (397.80) | |||||
Negative figures in brackets.
Fiscal years to Dec 2025 · latest quarter Jun 2026
Charts ten years each
Dyadic International Inc. vs peers in Biotechnology (Q) = latest quarter vs a year earlier
| Company | Market cap | P/E | Fwd P/E | Revenue growth (Q) | EPS growth (Q) | FCF growth (Q) | Gross margin (Q) | EBIT margin (Q) | Compare |
|---|---|---|---|---|---|---|---|---|---|
| ATYR aTyr Pharma, Inc. | $18.0M | — (loss-making) | — (loss-making) | −90.75% (below 0%: shrinking) | n/m | +32.22% (above 0%: growing) | 100.00% | 0.00% | Compare |
| NEUP Neuphoria Therapeutics Inc. | $17.9M | — (loss-making) | — (loss-making) | −107.32% (below 0%: shrinking) | n/m | +133.86% (above 0%: growing) | 100.00% | 0.00% | Compare |
| JSPR Jasper Therapeutics, Inc. | $17.7M | — (loss-making) | — | — | n/m | +55.74% (above 0%: growing) | 0.00% | 0.00% | Compare |
| ANEB Anebulo Pharmaceuticals, Inc. | $17.6M | — (loss-making) | — | — | n/m | +6.58% (above 0%: growing) | — | 0.00% | Compare |
| ACGN Aceragen, Inc. | $17.1M | — (loss-making) | — (loss-making) | +2,394.95% (above 0%: growing) | n/m | −115.67% (below 0%: shrinking) | 100.00% | (834.33%) | Compare |
| RADX Radiopharm Theranostics Limited - Sponsored ADR | $17.0M | — | — | — | — | −137.75% (below 0%: shrinking) | — | — | Compare |
| DYAI Dyadic International Inc. | $16.8M | — (loss-making) | — (loss-making) | −0.57% (below 0%: shrinking) | n/m | −1,298.54% (below 0%: shrinking) | (2.39%) | (213.73%) | |
| PBM Psyence Biomedical Ltd. | $16.5M | 0.2× | — | — | n/m | −707.20% (below 0%: shrinking) | — | 0.00% | Compare |
| TCRX TScan Therapeutics, Inc. | $16.2M | — (loss-making) | — (loss-making) | −65.83% (below 0%: shrinking) | n/m | +18.95% (above 0%: growing) | 100.00% | (2,901.33%) | Compare |
| Median of peers | $17.4M | — | — | −78.29% | — | +12.76% | 100.00% | 0.00% |
Dyadic International Inc. (DYAI) key facts
- Concern: Dyadic International Inc.’s revenue for fiscal 2025 (year ended December 2025) was $3.1 million, down 11.6% from fiscal 2024.
- Dyadic International Inc. (DYAI) is a Biotechnology company in the Healthcare sector, listed on Nasdaq.
- As of October 16, 2026, DYAI traded at $0.41, a market capitalization of $16.8 million.
- Return on equity was −397.8% and debt-to-equity -2.11.
- Its Piotroski F-score is 2 out of 9 and its Altman Z-score is −12.37 (distress zone) for fiscal 2025.