Denali Therapeutics Inc.

DNLI Healthcare Biotechnology

Denali Therapeutics Inc.’s revenue for fiscal 2023 (year ended December 2023) was $330.5 million, up 204.7% from fiscal 2022.

Revenue
−94.0%
EPS
+150.3%
Free cash flow
−11.8%
Total debt
−1.89%

Quarter to September 2026, against a year earlier

20.12 0.40 +2.03%
Market cap
$3.2B
P/E
0.0×
Fwd P/E
−7.7×
Dividend yield
—
F-score
4/9
Altman Z
13.78
Beneish M
n/a
Dividend safety
n/a
Dec '16 Dec '17 Dec '18 Dec '19 Dec '20 Dec '21 Dec '22 Dec '23 Dec '24 Dec '25
Piotroski F-Score
— — — — 7 2 4 4 — —
P/E ratio
— — 0.00 0.00 214.77 0.00 0.00 0.00 — —
Altman Z-Score
— — 10.27 4.85 13.16 6.50 4.22 13.78 — —
P/S ratio
— — 14.82 62.43 27.19 111.38 31.98 8.89 — —
Altman Z″-Score (non-manufacturers)
— — 7.83 2.08 8.03 1.80 3.41 10.11 — —
P/FCF ratio
— — 40.96 0.00 22.10 0.00 0.00 0.00 — —
P/Operating CF
— — 20.54 (34.96) 17.76 (82.76) (47.73) (29.78) — —
P/B ratio
— — 3.50 4.22 7.93 5.63 3.33 2.85 — —
EV/Sales
— — 11.22 49.45 23.01 94.81 20.15 5.90 — —
EV/EBITDA
— — 0.00 0.00 108.30 0.00 0.00 0.00 — —
EV/FCF
— — 31.02 (7.78) 18.69 (20.98) (8.32) (5.26) — —
Current Ratio
19.98 28.92 14.67 9.48 20.86 2.37 3.77 13.65 8.46 9.16
Net Debt/EBITDA
2.08 4.71 11.14 1.65 (19.71) 2.90 3.87 4.62 1.61 1.56
Debt/Equity
0.00 0.00 0.00 0.17 0.06 0.06 0.05 0.00 0.00 0.01
ROE
157.85% (47.46%) (7.16%) (41.97%) 9.21% (27.51%) (32.52%) (14.01%) (37.40%) (45.69%)
ROA
(56.31%) (23.27%) (6.31%) (32.52%) 6.59% (19.32%) (22.76%) (11.11%) (33.45%) (40.69%)
ROIC
(71.72%) (94.57%) (35.11%) (274.53%) 0.00% (118.58%) 0.00% 0.00% (75.59%) (229.23%)
Return on Tangible Assets
(46.06%) (21.49%) (7.66%) (45.81%) 4.86% (52.09%) (30.97%) (14.08%) (51.72%) (59.97%)
Average Days of Receivables
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 — —
Earnings Yield
— — (1.98%) (11.83%) 0.47% (5.36%) (9.41%) (4.86%) — —
Free Cash Flow Yield
— — 2.44% (10.18%) 4.53% (4.06%) (7.57%) (12.62%) — —
Free Cash Flow per Share
(12.15) (5.31) 0.50 (1.77) 3.79 (1.81) (2.09) (2.70) (2.21) (2.44)
Book value per Share
39.61 31.13 5.90 4.13 10.56 7.92 8.30 7.50 7.48 5.87
Free Cash Flow
(78.04) (79.51) 46.72 (169.49) 413.06 (219.89) (262.55) (370.93) (363.61) (422.10)
EV/EBIT
— — 0.00 0.00 123.12 0.00 0.00 0.00 — —
Other line items

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Columns are period end dates · fundamentals updated 5 Nov 2026