Castle Biosciences, Inc.

CSTL Healthcare Diagnostics & Research

Castle Biosciences, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $344.2 million, up 3.66% from fiscal 2024. In the quarter to June 2026, revenue grew 20.1%, EPS fell 143.8%, free cash flow fell 43.3% and total debt was flat, each against the same quarter a year earlier. Revenue growth for five consecutive years.

31.96 1.84 −5.44%
Market cap
$1.0B
P/E
0.0×
Fwd P/E
−15.2×
Dividend yield
—
F-score
3/9
Altman Z
6.70
Beneish M
−3.49
Dividend safety
n/a
Dec '17 Dec '18 Dec '19 Dec '20 Dec '21 Dec '22 Dec '23 Dec '24 Dec '25
P/E ratio
0.00 0.00 0.00 0.00 0.00 0.00 0.00 41.00 0.00
Piotroski F-Score
— — — 4 1 2 5 7 3
Altman Z-Score
— — 6.15 33.28 13.21 7.59 5.56 6.74 6.70
P/S ratio
1.70 1.70 5.69 20.29 11.45 4.33 2.68 2.23 3.28
Altman Z″-Score (non-manufacturers)
— (6.93) 7.12 24.00 11.93 10.19 7.63 9.07 6.15
P/FCF ratio
0.00 0.00 48.54 248.40 0.00 0.00 0.00 20.25 39.74
Beneish M-Score
— — (2.01) (2.38) 11.61 (2.41) (2.37) (2.58) (3.49)
P/Operating CF
95.59 95.59 65.66 (2,956.01) (387.49) (98.92) 31.67 30.38 41.87
P/B ratio
0.00 0.00 3.47 3.06 2.62 1.49 1.50 1.62 2.39
EV/Sales
1.96 1.96 4.27 14.11 8.04 2.54 1.64 1.38 2.44
EV/EBITDA
0.00 0.00 23.03 0.00 0.00 0.00 0.00 25.44 0.00
EV/FCF
(13.90) (13.90) 36.41 172.70 (33.67) (7.39) (18.72) 12.51 29.55
Current Ratio
1.28 2.69 7.63 20.58 14.21 8.09 6.20 7.29 5.26
Net Debt/EBITDA
(1.78) (6.79) (7.67) 78.35 8.77 3.85 3.98 (15.73) 46.20
Debt/Equity
(1.27) (0.43) 0.30 0.00 0.02 0.03 0.00 0.02 0.02
ROE
28.65% 19.02% 20.95% (4.11%) (7.56%) (16.56%) (14.54%) 4.31% (5.21%)
ROA
(95.00%) (90.72%) 4.21% (3.68%) (6.94%) (14.76%) (12.76%) 3.71% (4.35%)
ROIC
0.00% 0.00% 40.21% (70.02%) (27.78%) (29.60%) (28.67%) 3.13% (14.72%)
Return on Tangible Assets
(521.83%) (78.67%) 2.89% (2.47%) (9.25%) (24.82%) (21.02%) 5.04% (6.20%)
Average Days of Receivables
123.46 193.67 103.09 74.34 67.05 62.53 63.61 56.30 46.00
Earnings Yield
(24.42%) (24.42%) (3.52%) (0.76%) (2.89%) (11.33%) (9.84%) 2.44% (2.16%)
Free Cash Flow Yield
(8.33%) (8.33%) 2.06% 0.40% (2.08%) (7.93%) (3.27%) 4.94% 2.52%
Free Cash Flow per Share
(0.73) (6.60) 0.71 0.27 (0.89) (1.81) (0.72) 1.32 0.98
Book value per Share
(0.95) (29.68) 9.92 21.96 16.38 15.32 14.60 16.41 16.24
Free Cash Flow
(12.23) (12.57) 6.08 5.12 (22.46) (47.09) (19.23) 36.56 28.37
EV/EBIT
0.00 0.00 30.20 0.00 0.00 0.00 0.00 52.76 0.00
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