AnaptysBio, Inc.

ANAB Healthcare Biotechnology

AnaptysBio, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $234.6 million, up 157.0% from fiscal 2024. In the quarter to March 2026, revenue fell 7.98%, EPS fell 43.8% and free cash flow fell 141.6%, each against the same quarter a year earlier. Revenue growth for three consecutive years.

46.61 2.10 −4.31%
Market cap
$1.5B
P/E
0.0×
Fwd P/E
220×
Dividend yield
—
F-score
5/9
Altman Z
0.84
Beneish M
−2.34
Dividend safety
n/a
Dec '16 Dec '17 Dec '18 Dec '19 Dec '20 Dec '21 Dec '22 Dec '23 Dec '24 Dec '25
P/E ratio
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Piotroski F-Score
2 3 4 3 5 3 2 4 3 5
Altman Z-Score
— 36.84 27.96 5.20 12.03 1.44 0.19 (1.45) (1.47) 0.84
P/S ratio
1.79 83.01 59.07 18.32 4.71 10.06 53.33 22.71 2.75 3.96
P/FCF ratio
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 47.40
Altman Z″-Score (non-manufacturers)
4.13 18.15 26.06 15.85 24.50 4.57 1.64 (1.26) (1.29) (0.30)
P/Operating CF
(5.36) (275.76) (85.38) (18.54) 10.41 (25.12) (51.35) (11.34) (3.76) 9.48
Beneish M-Score
1.11 (2.33) (4.21) — — — 3.11 (1.09) 1.51 (2.34)
P/B ratio
0.00 4.31 2.16 0.72 0.99 1.78 2.09 4.42 3.54 24.98
EV/Sales
(0.45) 67.94 35.16 (4.92) 0.00 1.42 10.68 0.06 (1.45) 2.64
EV/EBITDA
2.69 0.00 0.00 0.72 0.00 0.00 0.00 0.00 1.08 13.61
EV/FCF
0.83 (55.02) (12.60) 1.12 0.00 (1.90) (1.49) (0.01) 0.98 31.63
Current Ratio
10.20 17.93 19.89 12.79 20.01 34.40 17.16 10.87 9.51 9.07
Net Debt/EBITDA
13.40 8.42 6.31 3.44 18.06 10.11 3.83 2.27 3.14 (6.84)
Debt/Equity
0.35 0.02 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
ROE
11.60% (22.33%) (15.53%) (21.84%) (4.97%) (15.35%) (41.62%) (93.44%) (182.71%) (24.49%)
ROA
(7.19%) (15.36%) (14.71%) (20.62%) (4.68%) (10.91%) (20.54%) (30.79%) (31.02%) (3.12%)
ROIC
(102.47%) (26.96%) (70.34%) (218.14%) (484.87%) 0.00% 0.00% 0.00% 0.00% 0.00%
Return on Tangible Assets
(8.04%) (12.57%) (14.90%) (27.82%) (5.27%) (10.70%) (30.41%) (44.04%) (37.40%) (4.23%)
Average Days of Receivables
116.89 58.44 12.70 0.00 0.00 5.06 50.35 145.75 163.01 52.66
Earnings Yield
(14.26%) (2.43%) (5.88%) (33.33%) (5.09%) (9.04%) (23.46%) (42.02%) (59.00%) (0.90%)
Free Cash Flow Yield
(30.39%) (1.49%) (4.72%) (24.00%) (3.76%) (7.44%) (13.48%) (31.21%) (54.15%) 2.11%
Free Cash Flow per Share
(3.44) (1.00) (2.01) (2.60) (0.54) (1.72) (2.63) (4.52) (4.78) 0.68
Book value per Share
14.89 15.55 19.71 14.97 14.53 12.99 9.31 3.27 2.50 1.29
Free Cash Flow
(9.08) (19.73) (49.57) (70.32) (14.73) (47.27) (73.95) (121.61) (135.69) 19.61
EV/EBIT
2.48 0.00 0.00 0.73 0.00 0.00 0.00 0.00 1.15 12.95
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