Akari Therapeutics PLC AKTX

9.76 (0.30) (2.98%) as of 25 Sep
Market cap
$17.6M
P/E
0.0×
Growth Flags show if company had growth for consecutive years

Insider Decisions

in millions of $
Nov 25 Feb 26 May 26 Aug 26
Buy — — — — — — — — — — — —
Sell — — — — — — — — — — — —
Insider Ownership 2.87%

Capital & Financial Ratios

Market Cap 17.61
Revenue —
Net Income (30.96)
Free Cash Flow (10.76)
Net Debt (7.06)
Current Ratio 0.60
Debt/Equity 0.04
P/E ratio 0.00
P/S ratio 0.00
P/B ratio 0.94
Past 5Y EPS Growth 37.49%
This Y EPS Growth 52.32%
Next Y EPS Growth 44.32%
Next 5Y EPS Growth 46.65%
in millions of $

Dividends

Payout Ratio 0.00
Annual Dividend Rate —
Annual Dividend Yield —
total individual payouts
2023 Powerpack
2022 Powerpack
2021 Powerpack
2020 Powerpack
2019 Powerpack
predictions in italic, special payouts not included in total or ratios

Assets vs Liabilities

2023 2024 2025 Q'26
Cash 4 3 5 8
Receivables — — — —
Inventory — — — —
Other 0 0 0 1
4 3 5 8
2023 2024 2025 Q'26
Payables 2 12 9 9
ST’ Debt — 1 1 1
Other 1 1 0 0
5 20 12 14
in millions of $

Compound Annual Growth

10y 5y 3y
Sales — — —
Cash Flow 0.00% 0.00% 0.00%
Earnings 0.00% 0.00% 0.00%
Book Value (5.28%) 24.73% 151.02%

Revenue

Year
in millions of $ · fiscal quarters ending in the months shown

Operating Cash Flow

Mar Jun Sep Dec Year
’26 (2) (3) — — —
’25 (2) (3) (2) (3) (11)
’24 (4) (5) (1) (2) (13)
’23 (5) (5) (2) (4) (16)
’22 (5) (9) — — (22)
’21 (7) (5) (2) (5) (19)
’20 (8) (4) (1) (4) (17)
in millions of $ · fiscal quarters ending in the months shown

Free Cash Flow

Mar Jun Sep Dec Year
’26 (2) (3) — — —
’25 (2) (3) (2) (3) (11)
’24 (4) (5) (1) (2) (13)
’23 (5) (5) (2) (4) (16)
’22 (5) (9) — — (22)
’21 (7) (5) (2) (5) (19)
’20 (8) (4) (1) (4) (17)
in millions of $ · fiscal quarters ending in the months shown

EPS

Mar Jun Sep Dec Year
’26 (9.74) (2.68) — — —
’25 (5.43) (1.67) (7.84) (5.61) (20.55)
’24 (33.10) (32.10) (9.50) 0.00 (66.28)
’23 10.71 (0.68) (22.70) (38.17) (81.79)
’22 (80.00) (80.00) — — (224.00)
’21 (120.00) (88.00) (24.00) (96.00) (328.00)
’20 (104.00) (224.00) 21.58 (176.00) (432.00)
fiscal quarters ending in the months shown

Target Price Range

Analyst price targets

Recommendation Rating

1
1Buy 2 3Hold 4 5Sell
2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 2027 2028
5,368.00 2,546.40 1,248.00 1,272.00 696.00 1,056.00 304.80 106.00 36.00 8.72

Analyst estimates 2026–2028

Powerpack
Low Price
15,802.40 17,760.00 3,600.00 7,360.00 2,232.00 3,368.00 1,288.00 440.00 176.00 69.20
High Price
15 17 13 10 9 9 15 12 8 6
Employees
0 0 0 0 0 0 0 0 0 0
Revenue/Emp
— — — — — — — — — —
Revenue
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% — — —
Gross Margin
(18) (35) (16) (17) (17) (17) (18) (10) (20) (18)
EBT
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
EBT Margin
(18) (35) (16) (17) (17) (17) (18) (10) (20) (17)
Net Income
0 0 0 0 0 0 0 0 0 —
Depreciation
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Revenue/Sh
(1,232.30) (2,270.46) (855.25) (744.00) (432.00) (328.00) (224.00) (81.79) (66.28) (20.55)
Earnings/Sh
(1,675.14) (2,025.56) (1,169.96) (564.12) (429.12) (350.96) (275.34) (134.25) (42.04) (12.56)
Cash Flow/Sh
(3.73) (2.37) 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Capex/Sh
(1,678.86) (2,027.92) (1,169.96) (564.12) (429.12) (350.96) (275.34) (134.25) (42.04) (12.56)
Free CF/Sh
2,319.90 1,099.62 161.21 0.33 237.58 103.44 22.93 (1.87) 74.44 33.66
Book Value/Sh
0 0 0 0 0 0 0 0 0 1
Shares
— — — — — — — — — —
PE Ratio
— — — — — — — — — —
PS Ratio
— — — — — — — — — —
PB Ratio
— — — — — — — — — —
EV/Sales
— — — — — — — — — —
EV/FCF
(25) (32) (23) (13) (17) (19) (22) (16) (13) (11)
Op' Cash Flow
0 0 — — — — — — — —
Capex
(25) (32) (23) (13) (17) (19) (22) (16) (13) (11)
FCF
34 17 3 0 9 6 2 0 (17) (7)
Working Cap'
— — 2 3 — — — — 1 1
Total Debt
(44) (28) (4) (3) (14) (9) (13) (4) (2) (5)
Net Debt
34 17 3 0 9 6 2 0 22 28
Sh' Equity
(31.34%) (94.49%) (88.82%) (232.21%) (162.03%) (132.74%) (139.31%) (110.06%) (72.08%) (35.14%)
ROA
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% (66.73%) (45.48%)
ROIC
(43.81%) (138.13%) (162.51%) (1,080.27%) (363.75%) (233.27%) (483.23%) (1,281.43%) (179.92%) (68.43%)
ROE
predictions in italic, sparklines do not include predictions

All 10 years →

Akari Therapeutics PLC peers in Biotechnology

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Akari Therapeutics PLC (AKTX) key facts

  • Akari Therapeutics PLC (AKTX) is a Biotechnology company in the Healthcare sector, traded in the US as an ADR.
  • As of September 25, 2026, AKTX traded at $9.76, a market capitalization of $17.6 million.
  • Return on equity was −68.4% and debt-to-equity 0.04.

Source: company filings (standardised) and stockrow calculations.

Akari Therapeutics PLC (AKTX) Latest News

News by impact score

Fine-tune

8 Sep

3

Akari Therapeutics PLC will showcase its novel PH1 ADC payload platform at leading global oncology, ADC and healthcare forums. Forum showcases raise visibility for Akari's ADC platform and may support future partnerships without immediate financial or market shifts.

18 Aug

4

Akari Therapeutics advances AKTX-101 with compelling urothelial cancer data that supports its differentiated ADC strategy. Positive clinical data on AKTX-101 strengthens drug pipeline prospects and can materially shift company trajectory.

13 Aug

4

Akari Therapeutics reported second quarter 2026 financial results, advanced AKTX-101 toward Phase 1 trials, and entered a strategic collaboration for its ADC payload platform. Pipeline advancement to Phase 1 plus new ADC collaboration represent major strategic progress likely to shift company trajectory and investor sentiment.

4 Aug

3

Akari Therapeutics PLC released a CEO Corner highlighting its strategic WhiteHawk collaboration and the expanding opportunity for dual-payload ADC innovation. WhiteHawk collaboration and dual-payload ADC focus may moderately affect Akari's innovation pipeline and positioning.

22 Jul

3

Akari Therapeutics CEO states rising demand for next-generation ADC payloads places company at center of major oncology opportunity. CEO positioning statement on ADC demand may moderately lift market sentiment and oncology focus without confirmed deals or results.

21 Jul

3

Akari Therapeutics PLC enters strategic research collaboration with Whitehawk Therapeutics. Strategic research collaboration may moderately support R&D efforts and market positioning.

29 Jun

3

Akari Therapeutics completed its previously announced PIPE financing, strengthening its balance sheet ahead of potential key clinical and regulatory milestones. PIPE completion adds capital to support operations and milestones without fundamentally altering company trajectory.

28 May

3

Akari Therapeutics announces first ASCO abstract acceptance, signaling clinical program progress for its pipeline candidates. ASCO abstract acceptance marks incremental R&D progress that can lift near-term sentiment but does not alter core operations or long-term trajectory.

3

Akari Therapeutics highlights breakthrough potential of AKTX-101 and spliceosome-modulating ADC platform in virtual investor segment after ASCO abstract acceptance. Abstract acceptance and pipeline discussion indicate moderate visibility gains for early-stage oncology assets.

21 May

4

Akari Therapeutics reported breakthrough preclinical data showing synergistic activity of AKTX-101 with KRAS inhibition in KRAS-mutated pancreatic cancer models. Breakthrough preclinical results on AKTX-101 in pancreatic cancer models can drive major advances in oncology pipeline and shift market positioning.

3

Akari Therapeutics PLC announces a $5.5 million private placement offering. Private placement supplies capital to support operations while introducing potential share dilution.

12 May

4

Akari Therapeutics secures key European patent for novel RNA splicing modulator ADC payload, strengthening global IP estate across all major markets. Securing a key patent for novel ADC payload technology bolsters Akari's competitive positioning and investor sentiment through enhanced global IP protection.

27 Apr

4

Akari Therapeutics PLC (AKTX) secures Australian patent approval for its proprietary PH1 RNA Splicing Modulator ADC Payload, expanding global IP protection. Australian patent bolsters AKTX's global IP for its core PH1 ADC payload, enhancing competitive edge and potential partnerships.

21 Apr

4

Akari Therapeutics PLC (AKTX) announces ASCO abstract acceptance, highlighting AKTX-101 ADC's potential to treat KRAS mutant tumors. ASCO abstract acceptance validates AKTX-101 ADC's promise against KRAS mutant tumors, a major oncology target, likely driving significant investor interest and pipeline momentum.

20 Apr

4

Akari Therapeutics announced positive preclinical data for AKTX-101, a first-in-class TROP2 ADC payload exhibiting differentiated cytotoxicity by targeting RNA splicing. Positive preclinical data for a first-in-class TROP2 ADC with novel RNA splicing mechanism could significantly enhance AKTX pipeline value and investor sentiment.

3

Maxim Group assesses Akari Therapeutics (AKTX) with a high risk profile due to substantial capital needs amid ongoing development of nomacopan for autoimmune and inflammatory diseases. Analyst caution on high risk from capital shortages could pressure financial performance and investor sentiment without altering core operations fundamentally.

9 Apr

4

Akari Therapeutics participated in a virtual investor 'What This Means' interview discussing its strategic partnership with WuXi XDC. Strategic partnership with WuXi XDC signals major advancement in Akari's biopharmaceutical development pipeline and competitive positioning.

6 Apr

4

Akari Therapeutics PLC (AKTX) announces strategic partnership with WuXi XDC to advance development of its novel ADC payload targeting RNA splicing. Strategic partnership with WuXi XDC validates and accelerates AKTX's innovative ADC payload development, boosting pipeline progress and investor sentiment.

13 Mar

4

Akari Therapeutics PLC (AKTX) released a CEO Corner where CEO Abizer Gaslightwala outlines strategic progress and the path to clinical development. CEO highlights strategic progress and clinical development roadmap under new leadership, signaling major shifts in company trajectory and investor sentiment.

11 Feb

3

Akari Therapeutics PLC participated in a virtual investor interview to discuss the expansion of its antibody-drug conjugate (ADC) pipeline. The company highlighted its strategic initiatives and advancements in developing innovative therapies aimed at addressing unmet medical needs. This engagement aims to enhance investor awareness and confidence in Akari's growth potential within the biopharmaceutical sector. The expansion of the ADC pipeline may moderately influence Akari's competitive positioning and market sentiment.

26 Jan

4

Akari Therapeutics PLC has filed a key patent and announced its second antibody-drug conjugate (ADC) program, AKTX-102, which targets CEACAM5 expressing solid tumors. This development aims to enhance the company's pipeline in oncology and potentially improve treatment options for patients with specific cancer types. The introduction of a new ADC program targeting solid tumors represents a significant strategic move that could enhance Akari's competitive positioning in the oncology market.

17 Jan

3

Akari Therapeutics PLC (AKTX) has been in the news for its recent developments, including updates on clinical trials and potential partnerships. The company is focusing on advancing its therapies for rare diseases, which could enhance its market position. Investors are closely monitoring these developments as they may influence the company's future performance and stock valuation. Recent clinical trial updates and potential partnerships may moderately influence Akari's financial performance and competitive positioning.

9 Jan

4

Akari Therapeutics PLC has released a new CEO Corner segment outlining the company's progress towards clinical transition in 2026, highlighting key developments and strategic goals for 2025. The segment emphasizes the company's commitment to advancing its pipeline and enhancing shareholder value as it prepares for upcoming clinical trials. The outlined strategic goals and clinical transition plans are likely to significantly impact the company's future performance and investor sentiment.

8 Jan

3

Akari Therapeutics PLC (AKTX) is set to present at the 2026 Biotech Showcase, highlighting its ongoing commitment to advancing its therapeutic pipeline. The event will provide a platform for the company to showcase its innovations and engage with potential investors and partners in the biotech sector. Participation in significant industry events can enhance visibility and networking opportunities, potentially influencing future funding and partnerships.

30 Dec

3

Akari Therapeutics PLC has issued its 2025 end-of-year letter to shareholders, outlining the company's progress, strategic initiatives, and future outlook. The letter highlights key achievements and ongoing projects aimed at enhancing shareholder value and advancing the company's mission in the biopharmaceutical sector. The letter outlines strategic initiatives and progress that may moderately influence the company's future performance and market sentiment.

23 Dec

4

Akari Therapeutics PLC has commenced GMP manufacturing of its AKTX-101 antibody-drug conjugate (ADC) program, which is intended to support a Phase 1 first-in-human clinical trial. This step marks a significant advancement in the development of AKTX-101, aimed at treating various diseases, and is expected to facilitate the initiation of clinical testing. Initiating GMP manufacturing for a clinical trial represents a major strategic move that could significantly impact the company's future performance and investor sentiment.

3

Insiders at Akari Therapeutics PLC purchased $1.81 million worth of stock, but the company's shares have since dropped by 36%. This decline may have taken these insiders by surprise, raising concerns about the company's future performance and market sentiment. The significant drop in stock price following insider purchases indicates potential concerns about the company's financial health and market perception.

18 Dec

3

Akari Therapeutics PLC has launched a virtual investor segment titled 'What This Means,' aimed at providing insights into the company's developments and future prospects. This initiative is designed to enhance communication with investors and clarify the implications of recent advancements in the company's pipeline. The launch of a virtual investor segment may moderately influence investor sentiment and communication but is not expected to significantly alter the company's overall trajectory.

16 Dec

3

Akari Therapeutics PLC has announced a $5 million financing initiative, which includes a concurrent registered direct offering and a private placement priced at market. This financing aims to support the company's ongoing development efforts and operational needs. The financing could provide necessary capital for development, impacting financial performance and operational capabilities.

9 Dec

4

Akari Therapeutics PLC announced promising preclinical data for its lead candidate, AKTX-101, targeting hard-to-treat K-Ras mutant pancreatic cancer. The data suggests significant therapeutic potential, positioning AKTX-101 as a noteworthy contender in the oncology space. This development may enhance the company's prospects in addressing a challenging cancer type, potentially leading to further research and clinical trials. The preclinical data indicates a significant advancement in treatment options for a difficult cancer, likely influencing investor sentiment and future strategic directions.

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