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OS Therapies Incorporated (OSTX) vs Spero Therapeutics, Inc. (SPRO)

OS Therapies Incorporated and Spero Therapeutics, Inc. are both Biotechnology companies. OS Therapies Incorporated and Spero Therapeutics, Inc. are of similar size ($66.0M and $65.8M). OS Therapies Incorporated has negative trailing earnings, so its P/E is not meaningful; Spero Therapeutics, Inc. trades at 7.9×. Across the 7 metrics below, Spero Therapeutics, Inc. leads on 6 and OS Therapies Incorporated on 1.

Valuation

Metric OSTX SPRO Biotechnology median
P/E n/m 7.86 8.50
P/S n/m 1.04 9.71
P/B n/m 1.44 2.13
Price to free cash flow n/m 3.26 20.82
EV/EBITDA n/m 2.16 0.64
EV/Sales n/m 0.21 9.21
Earnings yield (82.58%) 12.73% (33.15%)
Free cash flow yield (31.98%) 30.65% (25.50%)

Profitability

Metric OSTX SPRO Biotechnology median
Gross margin — 100.00% 65.16%
Operating margin 0.00% 0.00% 0.00%
Net margin 0.00% 0.00% 0.00%
Free cash flow margin 0.00% 0.00% 0.00%
Return on equity 1,129.52% 19.17% (56.36%)
Return on assets (389.65%) 12.85% (48.04%)
Return on invested capital 0.00% 0.00% 0.00%

Growth

Metric OSTX SPRO Biotechnology median
Revenue growth (TTM) — 37.24% 6.02%
EPS growth (last fiscal year) 23.32% 111.81% 30.26%
Revenue growth, 5-year CAGR — 48.25% 9.41%
Net income growth, 5-year CAGR — 0.00% 0.00%

Health

Metric OSTX SPRO Biotechnology median
Debt to equity 0.00 0.00 0.00
Current ratio 0.18 6.12 4.72
Net debt to EBITDA 0.01 (6.38) 0.96

Dividend

Metric OSTX SPRO Biotechnology median
Dividend yield — — 0.09%
Payout ratio — — —

Size

Metric OSTX SPRO Biotechnology median
Market cap 66.00m 65.80m 135.18m

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