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Madrigal Pharmaceuticals, Inc. (MDGL) vs Twist Bioscience Corporation (TWST)

Madrigal Pharmaceuticals, Inc. and Twist Bioscience Corporation are both Biotechnology companies. Madrigal Pharmaceuticals, Inc. and Twist Bioscience Corporation are of similar size ($10.1B and $9.9B). Madrigal Pharmaceuticals, Inc. grew revenue faster over the last twelve months: 149.0% against 19.2%. Madrigal Pharmaceuticals, Inc. has the higher net margin (−25.3% vs −31.7%) and the lower return on invested capital (−787.3% vs −30.8%). Across the 17 metrics below, Twist Bioscience Corporation leads on 9 and Madrigal Pharmaceuticals, Inc. on 8.

Valuation

Metric MDGL TWST Biotechnology median
P/E n/m n/m 12.43
P/S 9.77 22.08 10.53
P/B 23.95 21.39 2.24
Price to free cash flow n/m n/m 22.59
EV/EBITDA n/m n/m 0.69
EV/Sales 9.38 21.73 9.92
Earnings yield (3.00%) (1.45%) (34.94%)
Free cash flow yield (1.67%) (1.00%) (23.17%)

Profitability

Metric MDGL TWST Biotechnology median
Gross margin 91.48% 51.97% 68.94%
Operating margin (25.13%) (33.58%) 0.00%
Net margin (25.32%) (31.66%) 0.00%
Free cash flow margin (16.07%) (22.15%) 0.00%
Return on equity (53.31%) (29.59%) (54.09%)
Return on assets (28.77%) (20.78%) (46.84%)
Return on invested capital (787.33%) (30.83%) 0.00%

Growth

Metric MDGL TWST Biotechnology median
Revenue growth (TTM) 149.04% 19.19% 6.72%
EPS growth (last fiscal year) 41.32% 63.89% 29.36%
Revenue growth, 5-year CAGR — 33.11% 9.96%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric MDGL TWST Biotechnology median
Debt to equity 0.65 0.03 0.00
Current ratio 3.20 2.67 5.00
Net debt to EBITDA 2.21 1.95 1.01

Dividend

Metric MDGL TWST Biotechnology median
Dividend yield — — 0.40%
Payout ratio — — —

Size

Metric MDGL TWST Biotechnology median
Market cap 9.94b 10.06b 177.44m

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