Lexeo Therapeutics, Inc. (LXEO) vs Protalix BioTherapeutics, Inc. (PLX)

Lexeo Therapeutics, Inc. and Protalix BioTherapeutics, Inc. are both Biotechnology companies. Lexeo Therapeutics, Inc. and Protalix BioTherapeutics, Inc. are of similar size ($226.6M and $217.5M). Lexeo Therapeutics, Inc. has negative trailing earnings, so its P/E is not meaningful; Protalix BioTherapeutics, Inc. trades at 10.9×. Protalix BioTherapeutics, Inc. has the higher net margin (23.5% vs 0.00%) and the higher return on invested capital (48.5% vs −253.5%). Across the 14 metrics below, Protalix BioTherapeutics, Inc. leads on 10 and Lexeo Therapeutics, Inc. on 4.

Valuation

Metric LXEO PLX Biotechnology median
P/E n/m 10.92 8.50
P/S n/m 2.60 9.71
P/B 0.96 2.93 2.13
Price to free cash flow n/m 27.33 20.82
EV/EBITDA n/m 7.58 0.64
EV/Sales n/m 2.34 9.21
Earnings yield (43.56%) 9.16% (33.15%)
Free cash flow yield (39.24%) 3.66% (25.50%)

Profitability

Metric LXEO PLX Biotechnology median
Gross margin 0.00% 69.20% 65.16%
Operating margin 0.00% 28.89% 0.00%
Net margin 0.00% 23.50% 0.00%
Free cash flow margin 0.00% 9.51% 0.00%
Return on equity (46.76%) 31.23% (56.36%)
Return on assets (40.50%) 20.07% (48.04%)
Return on invested capital (253.48%) 48.48% 0.00%

Growth

Metric LXEO PLX Biotechnology median
Revenue growth (TTM) — 30.14% 6.02%
EPS growth (last fiscal year) 39.81% (300.00%) 30.26%
Revenue growth, 5-year CAGR — (3.46%) 9.41%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric LXEO PLX Biotechnology median
Debt to equity 0.00 0.00 0.00
Current ratio 13.89 2.94 4.72
Net debt to EBITDA 1.67 7.68 0.96

Dividend

Metric LXEO PLX Biotechnology median
Dividend yield — — 0.09%
Payout ratio — — —

Size

Metric LXEO PLX Biotechnology median
Market cap 226.56m 217.54m 135.18m

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