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Kyverna Therapeutics, Inc. (KYTX) vs Orchestra BioMed Holdings, Inc. (OBIO)

Kyverna Therapeutics, Inc. and Orchestra BioMed Holdings, Inc. are both Biotechnology companies. Kyverna Therapeutics, Inc. and Orchestra BioMed Holdings, Inc. are of similar size ($369.2M and $345.0M). Kyverna Therapeutics, Inc. has the higher net margin (0.00% vs −186.3%) and the higher return on invested capital (0.00% vs 0.00%). Across the 12 metrics below, Kyverna Therapeutics, Inc. leads on 9 and Orchestra BioMed Holdings, Inc. on 3.

Valuation

Metric KYTX OBIO Biotechnology median
P/E n/m n/m 8.50
P/S n/m 10.88 9.71
P/B 2.09 18.00 2.13
Price to free cash flow n/m n/m 20.82
EV/EBITDA n/m n/m 0.64
EV/Sales n/m 8.53 9.21
Earnings yield (51.85%) (15.60%) (33.15%)
Free cash flow yield (46.04%) (16.99%) (25.50%)

Profitability

Metric KYTX OBIO Biotechnology median
Gross margin — 99.51% 65.16%
Operating margin 0.00% (181.36%) 0.00%
Net margin 0.00% (186.30%) 0.00%
Free cash flow margin 0.00% (184.83%) 0.00%
Return on equity (87.24%) (607.32%) (56.36%)
Return on assets (68.40%) (75.16%) (48.04%)
Return on invested capital 0.00% 0.00% 0.00%

Growth

Metric KYTX OBIO Biotechnology median
Revenue growth (TTM) — 986.14% 6.02%
EPS growth (last fiscal year) (9.31%) 33.13% 30.26%
Revenue growth, 5-year CAGR — — 9.41%
Net income growth, 5-year CAGR — 0.00% 0.00%

Health

Metric KYTX OBIO Biotechnology median
Debt to equity 0.15 1.80 0.00
Current ratio 9.06 8.26 4.72
Net debt to EBITDA 1.51 1.80 0.96

Dividend

Metric KYTX OBIO Biotechnology median
Dividend yield — — 0.09%
Payout ratio — — —

Size

Metric KYTX OBIO Biotechnology median
Market cap 369.21m 345.00m 135.18m

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