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ImmunityBio, Inc. (IBRX) vs Spyre Therapeutics, Inc. (SYRE)

ImmunityBio, Inc. and Spyre Therapeutics, Inc. are both Biotechnology companies. ImmunityBio, Inc. and Spyre Therapeutics, Inc. are of similar size ($9.2B and $8.5B). ImmunityBio, Inc. grew revenue faster over the last twelve months: 192.9% against −81.8%. Spyre Therapeutics, Inc. has the higher net margin (0.00% vs −598.6%) and the higher return on invested capital (0.00% vs 0.00%). Across the 16 metrics below, Spyre Therapeutics, Inc. leads on 9 and ImmunityBio, Inc. on 7.

Valuation

Metric IBRX SYRE Biotechnology median
P/E n/m n/m 10.26
P/S 51.05 8,159.98 9.18
P/B n/m 9.50 2.05
Price to free cash flow n/m n/m 24.81
EV/EBITDA n/m n/m 0.65
EV/Sales 56.47 7,142.99 8.98
Earnings yield (12.03%) (3.16%) (34.89%)
Free cash flow yield (3.40%) (2.89%) (24.52%)

Profitability

Metric IBRX SYRE Biotechnology median
Gross margin 99.34% 100.00% 65.16%
Operating margin (151.88%) 0.00% 0.00%
Net margin (598.56%) 0.00% 0.00%
Free cash flow margin (173.76%) 0.00% 0.00%
Return on equity 122.85% (41.15%) (50.12%)
Return on assets (192.58%) (30.89%) (45.60%)
Return on invested capital 0.00% 0.00% 0.00%

Growth

Metric IBRX SYRE Biotechnology median
Revenue growth (TTM) 192.92% (81.84%) 6.26%
EPS growth (last fiscal year) 38.71% 55.24% 29.88%
Revenue growth, 5-year CAGR 184.76% (28.15%) 9.75%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric IBRX SYRE Biotechnology median
Debt to equity (0.74) 0.00 0.00
Current ratio 5.72 27.40 4.89
Net debt to EBITDA (0.97) 3.61 1.01

Dividend

Metric IBRX SYRE Biotechnology median
Dividend yield — — 0.41%
Payout ratio — — —

Size

Metric IBRX SYRE Biotechnology median
Market cap 8.49b 9.17b 172.11m

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