Humacyte, Inc. (HUMA) vs Spruce Biosciences, Inc. (SPRB)

Humacyte, Inc. and Spruce Biosciences, Inc. are both Biotechnology companies. Humacyte, Inc. and Spruce Biosciences, Inc. are of similar size ($122.1M and $119.2M). Humacyte, Inc. grew revenue faster over the last twelve months: 149.8% against −51.3%. Spruce Biosciences, Inc. has the higher net margin (0.00% vs −4,448.9%) and the higher return on invested capital (0.00% vs −433.7%). Across the 17 metrics below, Spruce Biosciences, Inc. leads on 13 and Humacyte, Inc. on 4.

Valuation

Metric HUMA SPRB Biotechnology median
P/E n/m n/m 8.50
P/S 47.48 19.63 9.71
P/B 3.22 1.15 2.13
Price to free cash flow n/m n/m 20.82
EV/EBITDA n/m n/m 0.64
EV/Sales 40.30 1.46 9.21
Earnings yield (113.95%) (100.33%) (33.15%)
Free cash flow yield (96.88%) (44.38%) (25.50%)

Profitability

Metric HUMA SPRB Biotechnology median
Gross margin (494.58%) 100.00% 65.16%
Operating margin (5,240.78%) 0.00% 0.00%
Net margin (4,448.89%) 0.00% 0.00%
Free cash flow margin (4,599.72%) 0.00% 0.00%
Return on equity (534.42%) (105.98%) (56.36%)
Return on assets (68.16%) (82.38%) (48.04%)
Return on invested capital (433.66%) 0.00% 0.00%

Growth

Metric HUMA SPRB Biotechnology median
Revenue growth (TTM) 149.82% (51.32%) 6.02%
EPS growth (last fiscal year) 79.37% 47.59% 30.26%
Revenue growth, 5-year CAGR — — 9.41%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric HUMA SPRB Biotechnology median
Debt to equity 2.07 0.08 0.00
Current ratio 6.21 9.23 4.72
Net debt to EBITDA (0.12) 1.34 0.96

Dividend

Metric HUMA SPRB Biotechnology median
Dividend yield — — 0.09%
Payout ratio — — —

Size

Metric HUMA SPRB Biotechnology median
Market cap 122.09m 119.19m 135.18m

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