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CRISPR Therapeutics AG (CRSP) vs Edgewise Therapeutics, Inc. (EWTX)

CRISPR Therapeutics AG and Edgewise Therapeutics, Inc. are both Biotechnology companies. CRISPR Therapeutics AG is the larger, with a market value of $4.7B against $4.2B — 1.1× the size. CRISPR Therapeutics AG has negative trailing earnings, so its P/E is not meaningful; Edgewise Therapeutics, Inc. trades at 4.9×. Edgewise Therapeutics, Inc. has the higher net margin (0.00% vs −1,812.1%) and the higher return on invested capital (0.00% vs 0.00%). Across the 13 metrics below, Edgewise Therapeutics, Inc. leads on 10 and CRISPR Therapeutics AG on 3.

Valuation

Metric CRSP EWTX Biotechnology median
P/E n/m 4.85 10.60
P/S 191.85 n/m 9.40
P/B 2.93 2.99 2.13
Price to free cash flow n/m n/m 25.18
EV/EBITDA n/m n/m 0.66
EV/Sales 124.89 n/m 9.02
Earnings yield (9.50%) 20.61% (32.88%)
Free cash flow yield (7.80%) (4.14%) (23.13%)

Profitability

Metric CRSP EWTX Biotechnology median
Gross margin 100.00% 0.00% 68.51%
Operating margin (2,114.75%) 0.00% 0.00%
Net margin (1,812.07%) 0.00% 0.00%
Free cash flow margin (1,496.56%) 0.00% 0.00%
Return on equity (25.60%) 92.15% (51.96%)
Return on assets (19.00%) 85.43% (46.06%)
Return on invested capital 0.00% 0.00% 0.00%

Growth

Metric CRSP EWTX Biotechnology median
Revenue growth (TTM) (34.34%) — 6.76%
EPS growth (last fiscal year) (49.08%) (12.41%) 29.88%
Revenue growth, 5-year CAGR 37.31% — 9.75%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric CRSP EWTX Biotechnology median
Debt to equity 0.36 0.00 0.00
Current ratio 16.21 12.30 4.97
Net debt to EBITDA 3.06 2.69 1.01

Dividend

Metric CRSP EWTX Biotechnology median
Dividend yield — — 0.41%
Payout ratio — — —

Size

Metric CRSP EWTX Biotechnology median
Market cap 4.71b 4.22b 161.82m

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