Aytu BioPharma, Inc. (AYTU) vs Shuttle Pharmaceuticals Holdings, Inc. (SHPH)

Aytu BioPharma, Inc. and Shuttle Pharmaceuticals Holdings, Inc. are both Drug Manufacturers Specialty & Generic companies. Shuttle Pharmaceuticals Holdings, Inc. is the larger, with a market value of $26.5M against $21.8M — 1.2× the size. Aytu BioPharma, Inc. has negative trailing earnings, so its P/E is not meaningful; Shuttle Pharmaceuticals Holdings, Inc. trades at 0.2×. Shuttle Pharmaceuticals Holdings, Inc. has the higher net margin (0.00% vs −24.8%) and the lower return on invested capital (−36.7% vs −20.0%). Across the 14 metrics below, Aytu BioPharma, Inc. leads on 7 and Shuttle Pharmaceuticals Holdings, Inc. on 7.

Valuation

Metric AYTU SHPH Drug Manufacturers Specialty & Generic median
P/E n/m 0.17 19.25
P/S 0.44 n/m 2.11
P/B 0.71 0.27 1.78
Price to free cash flow 7.77 n/m 16.14
EV/EBITDA n/m n/m 12.58
EV/Sales 0.28 n/m 2.73
Earnings yield (67.16%) 586.62% (4.38%)
Free cash flow yield 12.87% (129.33%) 0.00%

Profitability

Metric AYTU SHPH Drug Manufacturers Specialty & Generic median
Gross margin 63.95% 0.00% 53.94%
Operating margin (14.44%) 0.00% 0.00%
Net margin (24.76%) 0.00% 0.00%
Free cash flow margin 5.62% 0.00% 0.00%
Return on equity (52.55%) (90.05%) (0.40%)
Return on assets (12.44%) (72.47%) (3.32%)
Return on invested capital (19.99%) (36.73%) 0.00%

Growth

Metric AYTU SHPH Drug Manufacturers Specialty & Generic median
Revenue growth (TTM) (13.27%) — 10.01%
EPS growth (last fiscal year) 46.30% 91.32% 49.06%
Revenue growth, 5-year CAGR (2.59%) — 6.74%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric AYTU SHPH Drug Manufacturers Specialty & Generic median
Debt to equity 0.48 0.00 0.05
Current ratio 1.13 0.11 2.31
Net debt to EBITDA 2.17 0.03 0.97

Dividend

Metric AYTU SHPH Drug Manufacturers Specialty & Generic median
Dividend yield — — 1.57%
Payout ratio — — 0.27

Size

Metric AYTU SHPH Drug Manufacturers Specialty & Generic median
Market cap 21.84m 26.54m 276.90m

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