Ardelyx, Inc. (ARDX) vs Prime Medicine, Inc. (PRME)

Ardelyx, Inc. and Prime Medicine, Inc. are both Biotechnology companies. Ardelyx, Inc. and Prime Medicine, Inc. are of similar size ($807.1M and $751.6M). Ardelyx, Inc. grew revenue faster over the last twelve months: 17.6% against −17.9%. Ardelyx, Inc. has the higher net margin (−11.9% vs −4,613.1%) and the lower return on invested capital (−17.2% vs 0.00%). Across the 17 metrics below, Ardelyx, Inc. leads on 12 and Prime Medicine, Inc. on 5.

Valuation

Metric ARDX PRME Biotechnology median
P/E n/m n/m 10.60
P/S 1.53 200.59 9.40
P/B 4.36 20.52 2.13
Price to free cash flow n/m n/m 25.18
EV/EBITDA n/m n/m 0.66
EV/Sales 1.51 177.25 9.02
Earnings yield (7.79%) (23.95%) (32.88%)
Free cash flow yield (2.23%) (19.20%) (23.13%)

Profitability

Metric ARDX PRME Biotechnology median
Gross margin 94.46% 100.00% 68.51%
Operating margin (7.71%) (4,824.94%) 0.00%
Net margin (11.85%) (4,613.11%) 0.00%
Free cash flow margin (3.41%) (3,850.92%) 0.00%
Return on equity (34.85%) (373.29%) (51.96%)
Return on assets (10.33%) (71.16%) (46.06%)
Return on invested capital (17.21%) 0.00% 0.00%

Growth

Metric ARDX PRME Biotechnology median
Revenue growth (TTM) 17.57% (17.90%) 6.76%
EPS growth (last fiscal year) (52.94%) 18.18% 29.88%
Revenue growth, 5-year CAGR 121.90% — 9.75%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric ARDX PRME Biotechnology median
Debt to equity 1.54 0.00 0.00
Current ratio 3.45 3.05 4.97
Net debt to EBITDA 1.63 0.88 1.01

Dividend

Metric ARDX PRME Biotechnology median
Dividend yield — — 0.41%
Payout ratio — — —

Size

Metric ARDX PRME Biotechnology median
Market cap 751.61m 807.12m 161.82m

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