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Aprea Therapeutics, Inc. (APRE) vs Synlogic, Inc. (SYBX)

Aprea Therapeutics, Inc. and Synlogic, Inc. are both Biotechnology companies. Aprea Therapeutics, Inc. and Synlogic, Inc. are of similar size ($6.7M and $6.2M). Synlogic, Inc. grew revenue faster over the last twelve months: 188.7% against −81.0%. Across the 11 metrics below, Synlogic, Inc. leads on 7 and Aprea Therapeutics, Inc. on 4.

Valuation

Metric APRE SYBX Biotechnology median
P/E n/m n/m 10.60
P/S 97.70 4.26 9.40
P/B 0.82 1.14 2.13
Price to free cash flow n/m n/m 25.18
EV/EBITDA 0.65 n/m 0.66
EV/Sales (34.76) 0.15 9.02
Earnings yield (134.54%) (5.45%) (32.88%)
Free cash flow yield (45.64%) (26.92%) (23.13%)

Profitability

Metric APRE SYBX Biotechnology median
Gross margin 100.00% 100.00% 68.51%
Operating margin 0.00% 0.00% 0.00%
Net margin 0.00% 0.00% 0.00%
Free cash flow margin 0.00% 0.00% 0.00%
Return on equity (62.83%) (5.32%) (51.96%)
Return on assets (53.24%) (4.25%) (46.06%)
Return on invested capital 0.00% 0.00% 0.00%

Growth

Metric APRE SYBX Biotechnology median
Revenue growth (TTM) (80.99%) 188.74% 6.76%
EPS growth (last fiscal year) 17.87% 95.83% 29.88%
Revenue growth, 5-year CAGR — (67.55%) 9.75%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric APRE SYBX Biotechnology median
Debt to equity 0.00 0.00 0.00
Current ratio 9.67 9.19 4.97
Net debt to EBITDA 1.11 3.66 1.01

Dividend

Metric APRE SYBX Biotechnology median
Dividend yield — — 0.41%
Payout ratio — — —

Size

Metric APRE SYBX Biotechnology median
Market cap 6.24m 6.68m 161.82m

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