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Alumis Inc. (ALMS) vs Alto Neuroscience, Inc. (ANRO)

Alumis Inc. and Alto Neuroscience, Inc. are both Biotechnology companies. Alumis Inc. and Alto Neuroscience, Inc. are of similar size ($887.7M and $842.4M). Alto Neuroscience, Inc. has the higher net margin (0.00% vs −5,933.5%) and the higher return on invested capital (0.00% vs 0.00%). Across the 12 metrics below, Alto Neuroscience, Inc. leads on 8 and Alumis Inc. on 4.

Valuation

Metric ALMS ANRO Biotechnology median
P/E n/m n/m 8.50
P/S 105.63 n/m 9.71
P/B 1.73 4.31 2.13
Price to free cash flow n/m n/m 20.82
EV/EBITDA n/m n/m 0.64
EV/Sales 37.74 n/m 9.21
Earnings yield (63.07%) (10.97%) (33.15%)
Free cash flow yield (45.02%) (7.29%) (25.50%)

Profitability

Metric ALMS ANRO Biotechnology median
Gross margin 100.00% — 65.16%
Operating margin (6,204.39%) 0.00% 0.00%
Net margin (5,933.45%) 0.00% 0.00%
Free cash flow margin (4,755.33%) 0.00% 0.00%
Return on equity (93.65%) (49.17%) (56.36%)
Return on assets (74.94%) (40.90%) (48.04%)
Return on invested capital 0.00% 0.00% 0.00%

Growth

Metric ALMS ANRO Biotechnology median
Revenue growth (TTM) — — 6.02%
EPS growth (last fiscal year) 72.45% 12.40% 30.26%
Revenue growth, 5-year CAGR — — 9.41%
Net income growth, 5-year CAGR — — 0.00%

Health

Metric ALMS ANRO Biotechnology median
Debt to equity 0.00 0.09 0.00
Current ratio 6.74 14.85 4.72
Net debt to EBITDA 0.69 2.40 0.96

Dividend

Metric ALMS ANRO Biotechnology median
Dividend yield — — 0.09%
Payout ratio — — —

Size

Metric ALMS ANRO Biotechnology median
Market cap 842.35m 887.66m 135.18m

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