Agenus Inc. (AGEN) vs C4 Therapeutics, Inc. (CCCC)

Agenus Inc. and C4 Therapeutics, Inc. are both Biotechnology companies. Agenus Inc. and C4 Therapeutics, Inc. are of similar size ($375.3M and $372.8M). C4 Therapeutics, Inc. has negative trailing earnings, so its P/E is not meaningful; Agenus Inc. trades at 3.2×. Agenus Inc. grew revenue faster over the last twelve months: 30.5% against 2.33%. Agenus Inc. has the higher net margin (69.2% vs −289.4%) and the higher return on invested capital (0.00% vs 0.00%). Across the 16 metrics below, Agenus Inc. leads on 13 and C4 Therapeutics, Inc. on 3.

Valuation

Metric AGEN CCCC Biotechnology median
P/E 3.23 n/m 7.88
P/S 2.66 11.12 11.47
P/B n/m 1.58 2.52
Price to free cash flow n/m n/m 21.16
EV/EBITDA 9.48 n/m 0.74
EV/Sales 2.92 5.94 10.73
Earnings yield 30.99% (33.56%) (28.84%)
Free cash flow yield (27.80%) (21.93%) (23.03%)

Profitability

Metric AGEN CCCC Biotechnology median
Gross margin 99.52% 100.00% 65.16%
Operating margin 27.28% (318.97%) 0.00%
Net margin 69.18% (289.44%) 0.00%
Free cash flow margin (73.97%) (243.71%) 0.00%
Return on equity (33.86%) (48.14%) (57.72%)
Return on assets 51.30% (30.92%) (49.22%)
Return on invested capital 0.00% 0.00% 0.00%

Growth

Metric AGEN CCCC Biotechnology median
Revenue growth (TTM) 30.47% 2.33% 5.64%
EPS growth (last fiscal year) 100.00% 16.45% —
Revenue growth, 5-year CAGR 5.31% 1.61% 8.40%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric AGEN CCCC Biotechnology median
Debt to equity (0.15) 0.00 0.00
Current ratio 0.34 5.45 4.73
Net debt to EBITDA (4.10) 2.14 0.96

Dividend

Metric AGEN CCCC Biotechnology median
Dividend yield — — 2.10%
Payout ratio 0.00 0.00 0.00

Size

Metric AGEN CCCC Biotechnology median
Market cap 375.30m 372.77m 162.10m

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