Spruce Biosciences, Inc.

SPRB

Healthcare Biotechnology

Spruce Biosciences, Inc.’s revenue for fiscal 2024 (year ended December 2024) was $4.9 million, down 51.3% from fiscal 2023.

Revenue
−75.9%
EPS
−90.9%
Free cash flow
−152.1%
Total debt
+427.2%

Quarter to June 2026, against a year earlier

46.55 3.84 +8.99%
Market cap
$133.8M
P/E
n/m
Fwd P/E
n/m
Dividend yield
—
F-score
n/a
ROIC
0.00%
Net debt / EBITDA
1.3×
Dividend safety
n/a
Dec '17 Dec '18 Dec '19 Dec '20 Dec '21 Dec '22 Dec '23 Dec '24 Dec '25
P/E ratio
— — — — — — 0.00 0.00 —
P/S ratio
— — — — — — 11.27 3.53 —
Altman Z-Score
— — — — — — (0.85) (10.34) —
P/FCF ratio
— — — — — — 0.00 0.00 —
Altman Z″-Score (non-manufacturers)
— — — — — — (1.71) (20.34) —
P/Operating CF
— — — — — — (10.15) (0.84) —
P/B ratio
— — — — — — 1.49 0.60 —
EV/Sales
— — — — — — 2.06 (4.01) —
EV/EBITDA
— — — — — — 0.00 0.35 —
EV/FCF
— — — — — — (0.62) 0.35 —
Current Ratio
— 1.76 1.08 16.43 10.36 6.72 4.18 2.90 5.17
Net Debt/EBITDA
— 0.41 (0.04) 5.20 2.00 1.57 1.77 0.66 1.34
Debt/Equity
— 0.00 (1.57) 0.03 0.05 0.07 0.04 0.06 0.00
ROE
— 40.70% 54.04% (49.73%) (32.43%) (51.35%) (66.10%) (100.70%) (109.24%)
ROA
— (412.90%) (276.50%) (35.25%) (29.23%) (43.54%) (50.55%) (71.12%) (79.34%)
ROIC
— 0.00% 0.00% 0.00% (95.12%) 0.00% 0.00% 0.00% 0.00%
Return on Tangible Assets
— (476.69%) (3,750.14%) (19.61%) (50.94%) (64.90%) (61.66%) (183.14%) (92.72%)
Average Days of Receivables
— — — — — — 0.00 0.00 —
Earnings Yield
— — — — — — (42.78%) (305.43%) —
Free Cash Flow Yield
— — — — — — (29.26%) (322.97%) —
Free Cash Flow per Share
— (0.38) (1,237.35) (346.21) (115.77) (133.24) (64.98) (101.75) (43.45)
Book value per Share
— 0.09 (276.86) 1,874.87 358.45 218.88 149.37 52.40 55.43
Free Cash Flow
— (8.57) (12.62) (27.59) (35.97) (41.69) (33.28) (55.96) (33.33)
EV/EBIT
— — — — — — 0.00 0.35 —
Other line items

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Columns are period end dates · fundamentals updated 26 Oct 2026