CRISPR Therapeutics AG

CRSP Healthcare Biotechnology

CRISPR Therapeutics AG’s revenue for fiscal 2025 (year ended December 2025) was $3.5 million, down 90.6% from fiscal 2024.

Revenue
+1,325.1%
EPS
+1.55%
Free cash flow
−6.36%

Quarter to September 2026, against a year earlier

49.92 1.36 +2.80%
Market cap
$4.7B
P/E
0.0×
Fwd P/E
−11.8×
Dividend yield
—
F-score
2/9
Altman Z
7.04
Beneish M
n/a
Dividend safety
n/a
Dec '25 Dec '24 Dec '23 Dec '22 Dec '21 Dec '20 Dec '19 Dec '18 Dec '17 Dec '16
Piotroski F-Score
2 3 4 2 7 3 6 2 3 —
P/E ratio
0.00 0.00 0.00 0.00 15.19 0.00 54.87 0.00 0.00 0.00
Altman Z-Score
7.04 5.89 8.76 4.57 11.48 36.99 16.78 7.67 6.51 1.50
P/S ratio
1,343.49 88.98 14.10 2,660.79 6.29 14,043.96 11.44 438.65 24.59 53.41
Altman Z″-Score (non-manufacturers)
6.42 8.57 8.86 7.18 13.31 14.17 13.08 6.01 4.91 5.98
P/FCF ratio
0.00 0.00 0.00 0.00 12.59 0.00 66.27 0.00 0.00 0.00
P/Operating CF
(50.95) (66.37) (54.47) (28.13) (66.89) (124.34) 981.34 (48.30) (67.93) (14.20)
Beneish M-Score
— (4.94) 272.49 25,201.83 1,131.22 438.23 80.41 (7.56) 3.19 15.89
P/B ratio
2.45 1.72 2.78 1.70 2.40 6.07 3.53 3.49 5.37 1.18
EV/Sales
845.25 44.05 10.15 1,335.82 3.92 11,762.55 8.33 292.47 18.74 (7.69)
EV/EBITDA
0.00 0.00 0.00 0.00 9.17 0.00 46.89 0.00 0.00 0.59
EV/FCF
(8.58) (11.36) (13.96) (3.00) 7.85 (32.94) 48.27 (9.23) (9.86) 0.68
Current Ratio
13.32 22.07 17.54 15.30 20.17 18.21 17.29 16.81 17.12 14.56
Net Debt/EBITDA
3.06 4.26 8.36 2.80 (6.08) 4.92 (18.34) 2.94 3.89 4.69
Debt/Equity
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
ROE
(30.18%) (19.20%) (8.17%) (30.42%) 18.59% (26.80%) 10.04% (56.89%) (32.50%) (22.75%)
ROA
(25.81%) (16.38%) (6.87%) (26.03%) 16.49% (24.10%) 8.59% (43.40%) (22.18%) (9.19%)
ROIC
0.00% (1,032.08%) (73.55%) (699.33%) 1,148.27% 0.00% 0.00% 0.00% 0.00% 0.00%
Return on Tangible Assets
(29.79%) (18.47%) (7.87%) (34.30%) 15.51% (20.96%) 6.95% (36.09%) (27.05%) (7.26%)
Average Days of Receivables
0.00 244.55 196.66 3,351.42 0.12 73.10 0.12 10.28 23.38 223.14
Earnings Yield
(12.43%) (11.10%) (2.94%) (20.41%) 6.58% (3.44%) 1.82% (12.01%) (6.83%) (22.30%)
Free Cash Flow Yield
(7.34%) (4.36%) (5.16%) (16.72%) 7.94% (2.54%) 1.51% (7.23%) (7.73%) (21.15%)
Free Cash Flow per Share
(3.85) (1.71) (3.41) (6.85) 6.02 (3.89) 0.92 (2.06) (1.94) (4.76)
Book value per Share
21.37 22.90 23.77 24.12 31.59 25.23 17.27 8.18 4.69 19.00
Free Cash Flow
(345.93) (144.67) (269.84) (532.93) 457.27 (256.72) 49.99 (99.01) (77.91) (58.33)
EV/EBIT
0.00 0.00 0.00 0.00 9.61 0.00 51.63 0.00 0.00 0.58
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Columns are period end dates · fundamentals updated 6 Nov 2026