AstraZeneca PLC

AZN Healthcare Drug Manufacturers General

AstraZeneca PLC’s revenue for fiscal 2025 (year ended December 2025) was $58.7 billion, up 8.63% from fiscal 2024.

Revenue
+6.70%
EPS
+22.5%
Free cash flow
+1.99%
Total debt
+1.75%

Quarter to September 2026, against a year earlier

187.20 1.81 −0.96%
Market cap
$289.8B
P/E
26.3×
Fwd P/E
24.5×
Dividend yield
1.71%
F-score
9/9
Altman Z
3.52
Beneish M
−2.51
Dividend safety
54/100

AstraZeneca PLC (AZN) Operating margin

Alert me on Operating margin

AstraZeneca PLC's operating margin over the twelve months to 30 September 2026 was 23.7%, up 0.3 percentage points from fiscal 2025 (23.4%). Over the past ten years it has ranged from 2.82% (fiscal 2021) to 23.4% (fiscal 2025) — the current reading is the highest in ten years. That is above the Drug Manufacturers General industry median of 18.3% and above the Healthcare sector median of 0.00%.

Operating margin, annual

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Annual newest first

Period Operating margin Change (points)
FY2025 23.4% 4.90
FY2024 18.5% 0.62
FY2023 17.9% 9.41
FY2022 8.47% 5.65
FY2021 2.82% (16.57)
FY2020 19.4% 7.40
FY2019 12.0% (3.34)
FY2018 15.3% (1.04)
FY2017 16.4% (4.94)
FY2016 21.3% 4.66

Quarterly newest first

Period Operating margin Change (points)
Sep 2026 27.1% 6.50
Jun 2026 20.6% (7.20)
Mar 2026 27.8% 8.56
Dec 2025 19.2% (4.38)
43 more quarters

Against its own ten years

Low 2.82% High 23.4%
Ten-year median 16.7%
Current reading's percentile 93

Operating margin against peers

Company Operating margin
NVO Novo Nordisk A/S compare 43.4%
AMGN Amgen Inc. compare 32.4%
ABBV AbbVie Inc. compare 32.2%
NVS Novartis AG compare 25.2%
AZN AstraZeneca PLC 23.7%
BMY Bristol Myers Squibb Company compare 22.7%
PFE Pfizer Inc. compare 21.4%
MRK Merck & Co., Inc. compare 9.20%
GILD Gilead Sciences, Inc. compare −7.63%
Drug Manufacturers General industry median 18.3%
Healthcare sector median 0.00%
Market median 0.00%

What Operating margin is

EBIT Margin tells an investor how much operating profit, before interest and taxes, a company keeps from each unit of revenue.

EBIT ÷ Revenue

The full definition of Operating margin →

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