AstraZeneca PLC

AZN Healthcare Drug Manufacturers General

AstraZeneca PLC’s revenue for fiscal 2025 (year ended December 2025) was $58.7 billion, up 8.63% from fiscal 2024.

Revenue
+6.70%
EPS
+22.5%
Free cash flow
+1.99%
Total debt
+1.75%

Quarter to September 2026, against a year earlier

185.92 0.93 −0.50%
Market cap
$289.8B
P/E
26.3×
Fwd P/E
24.5×
Dividend yield
1.71%
F-score
9/9
Altman Z
3.52
Beneish M
−2.51
Dividend safety
54/100

AstraZeneca PLC (AZN) Gross margin

Alert me on Gross margin

AstraZeneca PLC's gross margin over the twelve months to 30 September 2026 was 81.9%, up 0.0 percentage points from fiscal 2025 (81.9%). Over the past ten years it has ranged from 66.8% (fiscal 2021) to 82.1% (fiscal 2016); the current reading is higher than 82% of that period. That is above the Drug Manufacturers General industry median of 73.0% and above the Healthcare sector median of 53.9%.

Gross margin, annual

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Annual newest first

Period Gross margin Change (points)
FY2025 81.9% 0.78
FY2024 81.1% (0.83)
FY2023 82.0% 9.89
FY2022 72.1% 5.30
FY2021 66.8% (13.33)
FY2020 80.1% 0.27
FY2019 79.8% 2.16
FY2018 77.7% (3.12)
FY2017 80.8% (1.28)
FY2016 82.1% 0.86

Quarterly newest first

Period Gross margin Change (points)
Sep 2026 81.8% (1.78)
Jun 2026 83.6% 1.12
Mar 2026 82.5% 2.59
Dec 2025 79.9% (1.67)
43 more quarters

Against its own ten years

Low 66.8% High 82.1%
Ten-year median 80.8%
Current reading's percentile 79

Gross margin against peers

Company Gross margin
AZN AstraZeneca PLC 81.9%
NVO Novo Nordisk A/S compare 80.7%
GILD Gilead Sciences, Inc. compare 79.9%
NVS Novartis AG compare 74.9%
ABBV AbbVie Inc. compare 73.7%
PFE Pfizer Inc. compare 73.4%
MRK Merck & Co., Inc. compare 71.8%
AMGN Amgen Inc. compare 70.9%
BMY Bristol Myers Squibb Company compare 69.2%
Drug Manufacturers General industry median 73.0%
Healthcare sector median 53.9%
Market median 45.1%

What Gross margin is

Gross Margin tells an investor how much of each sale a company keeps after paying the direct costs of making or buying what it sells.

Gross Profit ÷ Revenue

The full definition of Gross margin →

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