Stoke Therapeutics, Inc. (STOK) vs Taysha Gene Therapies, Inc. (TSHA)

Stoke Therapeutics, Inc. and Taysha Gene Therapies, Inc. are both Biotechnology companies. Stoke Therapeutics, Inc. and Taysha Gene Therapies, Inc. are of similar size ($1.6B and $1.6B). Taysha Gene Therapies, Inc. grew revenue faster over the last twelve months: 19.0% against −86.2%. Taysha Gene Therapies, Inc. has the higher net margin (0.00% vs −753.6%) and the higher return on invested capital (0.00% vs −264.8%). Across the 16 metrics below, Taysha Gene Therapies, Inc. leads on 12 and Stoke Therapeutics, Inc. on 4.

Valuation

Metric STOK TSHA Biotechnology median
P/E n/m n/m 7.88
P/S 59.35 146.12 11.47
P/B 4.74 4.45 2.52
Price to free cash flow n/m n/m 21.16
EV/EBITDA n/m n/m 0.74
EV/Sales 48.73 111.68 10.73
Earnings yield (13.59%) (8.99%) (28.84%)
Free cash flow yield (11.04%) (8.07%) (23.03%)

Profitability

Metric STOK TSHA Biotechnology median
Gross margin 100.00% 100.00% 65.16%
Operating margin (809.69%) 0.00% 0.00%
Net margin (753.60%) 0.00% 0.00%
Free cash flow margin (654.92%) 0.00% 0.00%
Return on equity (61.10%) (47.05%) (57.72%)
Return on assets (53.41%) (37.23%) (49.22%)
Return on invested capital (264.77%) 0.00% 0.00%

Growth

Metric STOK TSHA Biotechnology median
Revenue growth (TTM) (86.20%) 18.96% 5.64%
EPS growth (last fiscal year) 92.73% 5.56% —
Revenue growth, 5-year CAGR — — 8.40%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric STOK TSHA Biotechnology median
Debt to equity 0.00 0.13 0.00
Current ratio 7.69 17.76 4.73
Net debt to EBITDA 14.29 2.47 0.96

Dividend

Metric STOK TSHA Biotechnology median
Dividend yield — — 2.10%
Payout ratio 0.00 0.00 0.00

Size

Metric STOK TSHA Biotechnology median
Market cap 1.63b 1.56b 162.10m

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