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Prime Medicine, Inc. (PRME) vs WAVE Life Sciences Ltd. (WVE)

Prime Medicine, Inc. and WAVE Life Sciences Ltd. are both Biotechnology companies. Prime Medicine, Inc. and WAVE Life Sciences Ltd. are of similar size ($654.8M and $628.6M). Prime Medicine, Inc. grew revenue faster over the last twelve months: −17.9% against −30.4%. WAVE Life Sciences Ltd. has the higher net margin (−309.7% vs −4,613.1%) and the higher return on invested capital (0.00% vs 0.00%). Across the 14 metrics below, WAVE Life Sciences Ltd. leads on 9 and Prime Medicine, Inc. on 5.

Valuation

Metric PRME WVE Biotechnology median
P/E n/m n/m 8.50
P/S 150.99 9.74 9.71
P/B 15.45 1.40 2.13
Price to free cash flow n/m n/m 20.82
EV/EBITDA n/m n/m 0.64
EV/Sales 127.65 2.23 9.21
Earnings yield (30.93%) (34.94%) (33.15%)
Free cash flow yield (25.50%) (30.34%) (25.50%)

Profitability

Metric PRME WVE Biotechnology median
Gross margin 100.00% 100.00% 65.16%
Operating margin (4,824.94%) (333.36%) 0.00%
Net margin (4,613.11%) (309.73%) 0.00%
Free cash flow margin (3,850.92%) (295.46%) 0.00%
Return on equity (373.29%) (68.31%) (56.36%)
Return on assets (71.16%) (49.95%) (48.04%)
Return on invested capital 0.00% 0.00% 0.00%

Growth

Metric PRME WVE Biotechnology median
Revenue growth (TTM) (17.90%) (30.42%) 6.02%
EPS growth (last fiscal year) 18.18% (72.86%) 30.26%
Revenue growth, 5-year CAGR — 16.31% 9.41%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric PRME WVE Biotechnology median
Debt to equity 0.00 0.00 0.00
Current ratio 3.05 9.99 4.72
Net debt to EBITDA 0.88 2.92 0.96

Dividend

Metric PRME WVE Biotechnology median
Dividend yield — — 0.09%
Payout ratio — — —

Size

Metric PRME WVE Biotechnology median
Market cap 654.77m 628.58m 135.18m

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