Prime Medicine, Inc. (PRME) vs Valneva SE Sponsored ADR (VALN)

Prime Medicine, Inc. and Valneva SE Sponsored ADR are both Biotechnology companies. Prime Medicine, Inc. and Valneva SE Sponsored ADR are of similar size ($609.4M and $589.8M). Prime Medicine, Inc. has negative trailing earnings, so its P/E is not meaningful; Valneva SE Sponsored ADR trades at 65.3×. Prime Medicine, Inc. grew revenue faster over the last twelve months: −17.9% against −53.2%. Valneva SE Sponsored ADR has the higher net margin (−12.0% vs −4,613.1%) and the higher return on invested capital (0.00% vs 0.00%). Across the 16 metrics below, Valneva SE Sponsored ADR leads on 11 and Prime Medicine, Inc. on 5.

Valuation

Metric PRME VALN Biotechnology median
P/E n/m 65.32 7.88
P/S 126.19 3.33 11.47
P/B 12.91 5.80 2.52
Price to free cash flow n/m n/m 21.16
EV/EBITDA n/m 46.45 0.74
EV/Sales 102.84 3.78 10.73
Earnings yield (37.01%) 1.53% (28.84%)
Free cash flow yield (30.52%) (10.77%) (23.03%)

Profitability

Metric PRME VALN Biotechnology median
Gross margin 100.00% 38.28% 65.16%
Operating margin (4,824.94%) 13.56% 0.00%
Net margin (4,613.11%) (12.01%) 0.00%
Free cash flow margin (3,850.92%) 0.00% 0.00%
Return on equity (373.29%) 0.00% (57.72%)
Return on assets (71.16%) 0.00% (49.22%)
Return on invested capital 0.00% 0.00% 0.00%

Growth

Metric PRME VALN Biotechnology median
Revenue growth (TTM) (17.90%) (53.16%) 5.64%
EPS growth (last fiscal year) 18.18% (805.88%) —
Revenue growth, 5-year CAGR — 9.41% 8.40%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric PRME VALN Biotechnology median
Debt to equity 0.00 2.27 0.00
Current ratio 3.05 2.16 4.73
Net debt to EBITDA 0.88 (1.15) 0.96

Dividend

Metric PRME VALN Biotechnology median
Dividend yield — — 2.10%
Payout ratio — 0.00 0.00

Size

Metric PRME VALN Biotechnology median
Market cap 609.43m 589.78m 162.10m

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