CytomX Therapeutics, Inc. (CTMX) vs Prime Medicine, Inc. (PRME)

CytomX Therapeutics, Inc. and Prime Medicine, Inc. are both Biotechnology companies. CytomX Therapeutics, Inc. and Prime Medicine, Inc. are of similar size ($609.4M and $599.2M). Prime Medicine, Inc. grew revenue faster over the last twelve months: −17.9% against −87.0%. CytomX Therapeutics, Inc. has the higher net margin (−451.6% vs −4,613.1%) and the higher return on invested capital (0.00% vs 0.00%). Across the 14 metrics below, CytomX Therapeutics, Inc. leads on 11 and Prime Medicine, Inc. on 3.

Valuation

Metric CTMX PRME Biotechnology median
P/E n/m n/m 7.88
P/S 32.30 126.19 11.47
P/B 1.96 12.91 2.52
Price to free cash flow n/m n/m 21.16
EV/EBITDA n/m n/m 0.74
EV/Sales 14.45 102.84 10.73
Earnings yield (18.52%) (37.01%) (28.84%)
Free cash flow yield (13.98%) (30.52%) (23.03%)

Profitability

Metric CTMX PRME Biotechnology median
Gross margin 100.00% 100.00% 65.16%
Operating margin (476.19%) (4,824.94%) 0.00%
Net margin (451.62%) (4,613.11%) 0.00%
Free cash flow margin (450.27%) (3,850.92%) 0.00%
Return on equity (39.18%) (373.29%) (57.72%)
Return on assets (29.72%) (71.16%) (49.22%)
Return on invested capital 0.00% 0.00% 0.00%

Growth

Metric CTMX PRME Biotechnology median
Revenue growth (TTM) (87.03%) (17.90%) 5.64%
EPS growth (last fiscal year) (139.47%) 18.18% —
Revenue growth, 5-year CAGR (5.36%) — 8.40%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric CTMX PRME Biotechnology median
Debt to equity 0.00 0.00 0.00
Current ratio 9.36 3.05 4.73
Net debt to EBITDA 5.91 0.88 0.96

Dividend

Metric CTMX PRME Biotechnology median
Dividend yield — — 2.10%
Payout ratio 0.00 — 0.00

Size

Metric CTMX PRME Biotechnology median
Market cap 599.22m 609.43m 162.10m

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